The Search for AGN in Distant Galaxy Clusters

We are undertaking the first systematic study of the prevalence of AGN activity in a large sample of high redshift galaxy clusters. Local clusters contain mainly red elliptical galaxies, and have little or no luminous AGN activity. However, recent studies of some moderate to high redshift clusters have revealed significant numbers of luminous AGN within the cluster. This effect may parallel the Butcher-Oemler effect - the increase in the fraction of blue galaxies in distant clusters compared to local clusters. Our aim is to verify and quantify recent evidence that AGN activity in dense environments increases with redshift, and to evaluate the significance of this effect. As cluster AGN are far less prevalent than field sources, a large sample of over 120 cluster fields at z > 0.1 has been selected from the Chandra archives and is being analysed for excess point sources. The size of the excess, the radial distribution and flux of the sources and the dependence of these on cluster redshift and luminosity will reveal important information about the triggering and fueling of AGN.Comment: 2 pages, to appear in proceedings of 'Multi-wavelength AGN surveys', Cozumel, 200

Ion yields and erosion rates for Si1−xGex(0x1) ultralow energy O2+ secondary ion mass spectrometry in the energy range of 0.25–1 keV

We report the SIMS parameters required for the quantitative analysis of Si1−xGex across the range of 0 ≤ x ≤ 1 when using low energy O2+ primary ions at normal incidence. These include the silicon and germanium secondary ion yield [i.e., the measured ion signal (ions/s)] and erosion rate [i.e., the speed at which the material sputters (nm/min)] as a function of x. We show that the ratio Rx of erosion rates, Si1−xGex/Si, at a given x is almost independent of beam energy, implying that the properties of the altered layer are dominated by the interaction of oxygen with silicon. Rx shows an exponential dependence on x. Unsurprisingly, the silicon and germanium secondary ion yields are found to depart somewhat from proportionality to (1−x) and x, respectively, although an approximate linear relationship could be used for quantification across around 30% of the range of x (i.e., a reference material containing Ge fraction x would give reasonably accurate quantification across the range of ±0.15x). Direct comparison of the useful (ion) yields [i.e., the ratio of ion yield to the total number of atoms sputtered for a particular species (ions/atom)] and the sputter yields [i.e., the total number of atoms sputtered per incident primary ion (atoms/ions)] reveals a moderate matrix effect where the former decrease monotonically with increasing x except at the lowest beam energy investigated (250 eV). Here, the useful yield of Ge is found to be invariant with x. At 250 eV, the germanium ion and sputter yields are proportional to x for all x

Breeding and moult cycles of somes montane forest birds in south-central Africa

Etude de la nidification et de la mue des oiseaux des forêts de montagne du Plateau du Nyika (Malawi-Zambie) pendant trois ans consécutifs (1979-82

Updated recommendations for HER2 testing in the UK

This paper serves to update previously published guidance on rationale and methodology for HER2 laboratory testing following the recommendation for the use of HER2 targeted treatment in the management of advanced breast cancer in the UK. Emphasis is placed on the standardisation of methodology and assessment and strategies to achieve high quality performance. A two phase testing algorithm based on first line immunocytochemistry evaluation and second line fluorescence in situ hybridisation assessment of borderline cases is recommended. To ensure maintenance of expertise, an annual caseload volume of at least 250 cases is recommended for laboratories providing a testing service

Recommendations for HER2 testing in the UK

Determining the HER2 status of breast carcinomas is a prerequisite for the use of the monoclonal antibody trastuzumab (Herceptin(R)), which has recently been licensed for the treatment of metastatic disease. This necessitates a test based on archival material. The preferred analyses are immunohistochemistry with fluorescent in situ hybridisation (FISH) as a follow up test for ambiguous results. Guidelines have been developed for standardised, well controlled procedures for the provision of reliable results. A group of three reference laboratories has been established to provide advice, quality assurance, and materials, where needed

Exploring Fantasy Football Involvement and Mental Health through Player Experience, Engagement Levels, Social Comparisons, and Financial Incentives

Background Fantasy sports are a rapidly growing complement to the sports industry and recent research has explored the mental health experiences of those who play the game. Aim This study aimed to test the findings from two such studies (Wilkins et al., 2021; Wilkins et al., 2023). Methods Questionnaire data measuring depression, anxiety, stress, positive mood, negative mood, problematic behaviour, and functional impairment from 635 fantasy football players were analysed using one-way ANOVAs. Results Amongst the significant results were the findings that: i) more experienced players reported less anxiety than less experienced players, and ii) players who engaged more with the game, made more social comparisons, and had greater financial involvement generally reported more mental health concerns and more positive mood than other players. Conclusion Engagement levels play an important role in determining the wellbeing experience of fantasy football participants. These findings also lend support to the ‘Framework of Hypothesised Factors Leading to Predominantly Positive or Negative Experiences in FF’ and should be used by stakeholders within the fantasy sports industry to optimise the game-playing experience of participants

Dopant Spatial Distributions: Sample Independent Response Function And Maximum Entropy Reconstruction

We demonstrate the use of maximum entropy based deconvolution to reconstruct boron spatial distribution from the secondary ion mass spectrometry (SIMS) depth profiles on a system of variously spaced boron $\delta$-layers grown in silicon. Sample independent response functions are obtained using a new method which reduces the danger of incorporating real sample behaviour in the response. Although the original profiles of different primary ion energies appear quite differently, the reconstructed distributions agree well with each other. The depth resolution in the reconstructed data is increased significantly and segregation of boron at the near surface side of the $\delta$-layers is clearly shown.Comment: 5 two-columne pages, 3 postscript figures, to appear in Phys. Rev. B1