Leveraging Telematics and Weather Data to Study the Productivity of Roadside Mowers

The Indiana Department of Transportation (INDOT) is responsible for the construction and maintenance of approximately 11,000 centerline miles of state roads, US routes and interstates. Mowing operations along the state rights-of-way to manage vegetation consume considerable resources. Mowing activities are usually reported by daily work orders and it is difficult to obtain quantitative information characterizing the utilization and productivity of the mowing operations. This research uses telematics data from commercial sensors to track the daily activity of seven mowers in the Fort Wayne district. Weather data from NOAA was also captured to estimate the weather related delays. During a one-month period, the mowers collectively covered a total of around 1170 miles and an area of nearly 1800 acres of mowing. Crews worked alternative work schedules with extended hours four days a week. On an average 9.5 hour work day approximately 50% of the time is spent actively mowing. The simple telematics based metrics and visualization graphics proposed in this paper can be used by agencies to evaluate the efficiency of their mowing operations to provide guidance on resource allocation, scheduling, and comparison with alternative contract mowing. The proposed utilization graphics may be of particular interest to agencies as they provide a concise way of communicating to stakeholders the overall efficiency of the mowing operations and can be used to identify opportunities for efficiency improvements

Contributions of Fire Refugia to Resilient Ponderosa Pine and Dry Mixed‐Conifer Forest Landscapes

Altered fire regimes can drive major and enduring compositional shifts or losses of forest ecosystems. In western North America, ponderosa pine and dry mixed‐conifer forest types appear increasingly vulnerable to uncharacteristically extensive, high‐severity wildfire. However, unburned or only lightly impacted forest stands that persist within burn mosaics—termed fire refugia—may serve as tree seed sources and promote landscape recovery. We sampled tree regeneration along gradients of fire refugia proximity and density at 686 sites within the perimeters of 12 large wildfires that occurred between 2000 and 2005 in the interior western United States. We used generalized linear mixed‐effects models to elucidate statistical relationships between tree regeneration and refugia pattern, including a new metric that incorporates patch proximity and proportional abundance. These relationships were then used to develop a spatially explicit landscape simulation model. We found that regeneration by ponderosa pine and obligate‐seeding mixed‐conifer tree species assemblages was strongly and positively predicted by refugia proximity and density. Simulation models revealed that for any given proportion of the landscape occupied by refugia, small patches produced greater landscape recovery than large patches. These results highlight the disproportionate importance of small, isolated islands of surviving trees, which may not be detectable with coarse‐scale satellite imagery. Findings also illustrate the interplay between patch‐scale resistance and landscape‐scale resilience: Disturbance‐resistant settings (fire refugia) can entrain resilience (forest regeneration) across the burn matrix. Implications and applications for land managers and conservation practitioners include strategies for the promotion and maintenance of fire refugia as components of resilient forest landscapes

Molecular mechanisms of drug resistance in natural Leishmania populations vary with genetic background

The evolution of drug-resistance in pathogens is a major global health threat. Elucidating the molecular basis of pathogen drug-resistance has been the focus of many studies but rarely is it known whether a drug-resistance mechanism identified is universal for the studied pathogen; it has seldom been clarified whether drug-resistance mechanisms vary with the pathogen's genotype. Nevertheless this is of critical importance in gaining an understanding of the complexity of this global threat and in underpinning epidemiological surveillance of pathogen drug resistance in the field. This study aimed to assess the molecular and phenotypic heterogeneity that emerges in natural parasite populations under drug treatment pressure. We studied lines of the protozoan parasite Leishmania (L.) donovani with differential susceptibility to antimonial drugs; the lines being derived from clinical isolates belonging to two distinct genetic populations that circulate in the leishmaniasis endemic region of Nepal. Parasite pathways known to be affected by antimonial drugs were characterised on five experimental levels in the lines of the two populations. Characterisation of DNA sequence, gene expression, protein expression and thiol levels revealed a number of molecular features that mark antimonial-resistant parasites in only one of the two populations studied. A final series of in vitro stress phenotyping experiments confirmed this heterogeneity amongst drug-resistant parasites from the two populations. These data provide evidence that the molecular changes associated with antimonial-resistance in natural Leishmania populations depend on the genetic background of the Leishmania population, which has resulted in a divergent set of resistance markers in the Leishmania populations. This heterogeneity of parasite adaptations provides severe challenges for the control of drug resistance in the field and the design of molecular surveillance tools for widespread applicability

Different paths to the modern state in Europe: the interaction between domestic political economy and interstate competition

Theoretical work on state formation and capacity has focused mostly on early modern Europe and on the experience of western European states during this period. While a number of European states monopolized domestic tax collection and achieved gains in state capacity during the early modern era, for others revenues stagnated or even declined, and these variations motivated alternative hypotheses for determinants of fiscal and state capacity. In this study we test the basic hypotheses in the existing literature making use of the large date set we have compiled for all of the leading states across the continent. We find strong empirical support for two prevailing threads in the literature, arguing respectively that interstate wars and changes in economic structure towards an urbanized economy had positive fiscal impact. Regarding the main point of contention in the theoretical literature, whether it was representative or authoritarian political regimes that facilitated the gains in fiscal capacity, we do not find conclusive evidence that one performed better than the other. Instead, the empirical evidence we have gathered lends supports to the hypothesis that when under pressure of war, the fiscal performance of representative regimes was better in the more urbanized-commercial economies and the fiscal performance of authoritarian regimes was better in rural-agrarian economie

Rapid Risk Assessment: FY05 Annual Summary Report

The Pacific Northwest National Laboratory (PNNL) is developing decision support tools that will assist in the transition of incident information into Protective Action Recommendations (PARs) that are understandable and can be executed in a real-world, operational environment. During emergencies, responders must rapidly assess risks and decide on the best course of action—all within minutes to hours. PNNL is blending existing modeling and decision support technology to develop new methods for transitioning science-based threat assessment to PARs. The rapid risk assessment tool will be both understandable and applicable to the emergency management community and would be a valuable tool during any water security-related incident. In 2005, PNNL demonstrated the integration of the multi-thematic modeling with emergency management decision support tools to create a Rapid Risk Assessment (RRA) tool that will transition risk to PARs that assist in responding to or mitigating the direct and indirect impacts of the incident(s). The RRA tool does this by aligning multi-thematic modeling capabilities with real-world response zones established by emergency and site operations managers. The RRA tool uses the risk assessment tool to drive prognostic models that use the type of incident, time of impact, severity of impact, and duration of impact to select the most appropriate PAR. Because PARs (and the thresholds by which they are selected) are jointly established by the technologists and the emergency management and operations decision makers, the science-based risk assessment can transition into a recommendation that can be understood and executed by people in the field

Strategies to Control a Common Carp Population by Pulsed Commercial Harvest

Commercial fisheries are commonly used to manage nuisance fishes in freshwater systems, but such efforts are often unsuccessful. Strategies for successfully controlling a nuisance population of common carpCyprinus carpio by pulsed commercial harvest were evaluated with a combination of (1) field sampling, (2) population estimation and CPUE indexing, and (3) simulation using an exponential semidiscrete biomass dynamics model (SDBDM). The range of annual fishing mortalities (F) that resulted in successful control (F= 0.244–0.265) was narrow. Common carp biomass dynamics were sensitive to unintentional underharvest due to high rates of surplus production and a biomass doubling time of 2.7 years. Simulations indicated that biomanipulation never achieved successful control unless supplemental fishing mortality was imposed. Harvest of a majority of annual production was required to achieve successful control, as indicated by the ecotrophic coefficient (EC). Readily available biomass data and tools such as SDBDMs and ECs can be used in an adaptive management framework to successfully control common carp and other nuisance fishes by pulsed commercial fishing

U.S. Billion-ton Update: Biomass Supply for a Bioenergy and Bioproducts Industry

The Report, Biomass as Feedstock for a Bioenergy and Bioproducts Industry: The Technical Feasibility of a Billion-Ton Annual Supply (generally referred to as the Billion-Ton Study or 2005 BTS), was an estimate of “potential” biomass within the contiguous United States based on numerous assumptions about current and future inventory and production capacity, availability, and technology. In the 2005 BTS, a strategic analysis was undertaken to determine if U.S. agriculture and forest resources have the capability to potentially produce at least one billion dry tons of biomass annually, in a sustainable manner—enough to displace approximately 30% of the country’s present petroleum consumption. To ensure reasonable confidence in the study results, an effort was made to use relatively conservative assumptions. However, for both agriculture and forestry, the resource potential was not restricted by price. That is, all identified biomass was potentially available, even though some potential feedstock would more than likely be too expensive to actually be economically available. In addition to updating the 2005 study, this report attempts to address a number of its shortcoming

Scalable production of large quantities of defect-free few-layer graphene by shear exfoliation in liquids

To progress from the laboratory to commercial applications, it will be necessary to develop industrially scalable methods to produce large quantities of defect-free graphene. Here we show that high-shear mixing of graphite in suitable stabilizing liquids results in large-scale exfoliation to give dispersions of graphene nanosheets. X-ray photoelectron spectroscopy and Raman spectroscopy show the exfoliated flakes to be unoxidized and free of basal-plane defects. We have developed a simple model that shows exfoliation to occur once the local shear rate exceeds 10(4) s(-1). By fully characterizing the scaling behaviour of the graphene production rate, we show that exfoliation can be achieved in liquid volumes from hundreds of millilitres up to hundreds of litres and beyond. The graphene produced by this method performs well in applications from composites to conductive coatings. This method can be applied to exfoliate BN, MoS2 and a range of other layered crystals

Seasonal pulses of Marburg virus circulation in juvenile Rousettus aegyptiacus bats coincide with periods of increased risk of human infection

Marburg virus (family Filoviridae) causes sporadic outbreaks of severe hemorrhagic disease in sub-Saharan Africa. Bats have been implicated as likely natural reservoir hosts based most recently on an investigation of cases among miners infected in 2007 at the Kitaka mine, Uganda, which contained a large population of Marburg virus-infected Rousettus aegyptiacus fruit bats. Described here is an ecologic investigation of Python Cave, Uganda, where an American and a Dutch tourist acquired Marburg virus infection in December 2007 and July 2008. More than 40,000 R. aegyptiacus were found in the cave and were the sole bat species present. Between August 2008 and November 2009, 1,622 bats were captured and tested for Marburg virus. Q-RT-PCR analysis of bat liver/spleen tissues indicated ,2.5% of the bats were actively infected, seven of which yielded Marburg virus isolates. Moreover, Q-RT-PCR-positive lung, kidney, colon and reproductive tissues were found, consistent with potential for oral, urine, fecal or sexual transmission. The combined data for R. aegyptiacus tested from Python Cave and Kitaka mine indicate low level horizontal transmission throughout the year. However, Q-RT-PCR data show distinct pulses of virus infection in older juvenile bats (,six months of age) that temporarily coincide with the peak twiceyearly birthing seasons. Retrospective analysis of historical human infections suspected to have been the result of discrete spillover events directly from nature found 83% (54/65) events occurred during these seasonal pulses in virus circulation, perhaps demonstrating periods of increased risk of human infection. The discovery of two tags at Python Cave from bats marked at Kitaka mine, together with the close genetic linkages evident between viruses detected in geographically distant locations, are consistent with R. aegyptiacus bats existing as a large meta-population with associated virus circulation over broad geographic ranges. These findings provide a basis for developing Marburg hemorrhagic fever risk reduction strategies.The Department of Health and Human Serviceshttp://www.plospathogens.or