Agents of Soviet Decline: Mass Media Representations of Prostitution During Perestroika

In 1986, the Soviet newspaper Komsomolskaya pravda printed an article titled “Nina of Minsk” detailing the scandalous adventures of a prostitute-turned-brothel owner. The first of its kind, this article horrified and fascinated the Soviet reading public in equal measure, serving as an initial exposure to the topic of prostitution in the mass media. The conversation surrounding prostitution became more heated in light of the Soviet Union’s failing economy, as well as the policy of glasnost’, which freed the press from rigid censorship. Prostitution rapidly became a popular topic of debate due to its illicit nature and impact on labor and public health issues. In response to these concerns, individuals from all walks of life began writing letters to newspapers explaining their views on prostitution. This public conversation about prostitution thus reflected a broader set of social and economic anxieties, and offers historians specific insight into how the Soviet public was reacting to the economic turmoil that rocked the Soviet Union in the 1980s. This thesis will explore this conversation and how the mass media’s focus on prostitution reveals concerns about broader social issues, including shifting gender norms, standards of morality, and public health, more specifically associated with fears about the spread of AIDS

Analysis of the economic value associated with the adoption of beef reproductive technologies

Beef cattle herd improvement to meet growing demand for higher quality beef has been an aspiration within the cattle industry since inception. Throughout the heartland, progressive cow-calf producers invest and adopt research-proven practices striving to continually improve their herds, resulting in premium cattle and beef products. Advantages to modifying management practices and applying advanced genetics could aid modern cow-calf producers by minimizing calf loss, unifying calving windows, increasing weaning weights, raising daily feedlot gains, and improving carcass quality grades. This research evaluates aggregate data from the University of Missouri Thompson Research Center with a focus on realized values of offspring born from 2004 to 2017. By evaluating the difference in aggregate average values of offspring when compared to US averages over time, this research strives to quantify realized added value achieved through the adoption of innovative beef cattle reproductive management practices. The goal of this research is to provide producers suspect of using newer production methods an additional decision aid to measure potential added revenue.by Emma Jane DowningIncludes bibliographical reference

An Exploration of 1st and 2nd Generation CPTED for End of Year School Leavers at Rottnest Island

The end-of-year post exam celebrations for Year 12 secondary school students presents a unique crime prevention proposition in Australia each year. Students of approximately 17 years of age congregate in a variety of locations in large groups known as ‘Leavers’. Traditionally a number of \u27rite of passage\u27 activities, fuelled by additional factors such as alcohol, drugs and peer pressure, have resulted in an increased risk of crime and anti-social behaviour. This paper examines mitigation strategies aligned with Crime Prevention Through Environmental Design (CPTED) when placed at an event. Using the annual Leavers cohort at Rottnest Island, W.A., a number of 1st and 2nd generation CPTED instruments are discussed and evaluated. The additional isolation factor of the island highlights the value of 2nd generation social cohesion and its likely impact in reducing a number of crime-related social issues. The paper concludes that increased 2nd generation CPTED treatments significantly improve crime reduction and fear of crime in temporary locations when used for mass gatherings at events

An exploration of 1st and 2nd generation CPTED for end of year school leavers at Rottnest Island

The end-of-year post exam celebrations for Year 12 secondary school students presents a unique crime prevention proposition in Australia each year. Students of approximately 17 years of age congregate in a variety of locations in large groups known as ‘Leavers’. Traditionally a number of \u27rite of passage\u27 activities, fuelled by additional factors such as alcohol, drugs and peer pressure, have resulted in an increased risk of crime and anti-social behaviour. This paper examines mitigation strategies aligned with Crime Prevention Through Environmental Design (CPTED) when placed at an event. Using the annual Leavers cohort at Rottnest Island, W.A., a number of 1st and 2nd generation CPTED instruments are discussed and evaluated. The additional isolation factor of the island highlights the value of 2nd generation social cohesion and its likely impact in reducing a number of crime-related social issues. The paper concludes that increased 2nd generation CPTED treatments significantly improve crime reduction and fear of crime in temporary locations when used for mass gatherings at events

Evidence from big data in obesity research: international case studies

Obesity is thought to be the product of over 100 different factors, interacting as a complex system over multiple levels. Understanding the drivers of obesity requires considerable data, which are challenging, costly and time-consuming to collect through traditional means. Use of 'big data' presents a potential solution to this challenge. Big data is defined by Delphi consensus as: always digital, has a large sample size, and a large volume or variety or velocity of variables that require additional computing power (Vogel et al. Int J Obes. 2019). 'Additional computing power' introduces the concept of big data analytics. The aim of this paper is to showcase international research case studies presented during a seminar series held by the Economic and Social Research Council (ESRC) Strategic Network for Obesity in the UK. These are intended to provide an in-depth view of how big data can be used in obesity research, and the specific benefits, limitations and challenges encountered

Conservation organizations need to consider adaptive capacity: why local input matters

Conservation organizations are increasingly applying adaptive capacity assessments in response to escalating climate change impacts. These assessments are essential to identify climate risks to ecosystems, prioritize management interventions, maximize the effectiveness of conservation actions, and ensure conservation resources are allocated appropriately. Despite an extensive literature on the topic, there is little agreement on the most relevant factors needed to support local scale initiatives, and additional guidance is needed to clarify how adaptive capacity should be assessed. This article discusses why adaptive capacity assessment represents a critical tool supporting conservation planning and management. It also evaluates key factors guiding conservation NGOs conducting these assessments in tropical island communities, and explores alternative priorities based on input from academic experts and key local stakeholders. Our results demonstrate that important differences exist between local stakeholders and nonlocal academic experts on key factors affecting adaptation and coping mechanisms. The exclusion of local community input affects the validity of adaptive capacity assessment findings, and has significant implications for the prioritization and effectiveness of conservation strategies and funding allocation

Improving the diagnosis and treatment of urinary tract infection in young children in primary care:results from the ‘DUTY’ prospective diagnostic cohort study

PURPOSE Up to 50% of urinary tract infections (UTIs) in young children are missed in primary care. Urine culture is essential for diagnosis, but urine collection is often difficult. Our aim was to derive and internally validate a 2-step clinical rule using (1) symptoms and signs to select children for urine collection; and (2) symptoms, signs, and dipstick testing to guide antibiotic treatment. METHODS We recruited acutely unwell children aged under 5 years from 233 primary care sites across England and Wales. Index tests were parent-reported symptoms, clinician-reported signs, urine dipstick results, and clinician opinion of UTI likelihood (clinical diagnosis before dipstick and culture). The reference standard was microbiologically confirmed UTI cultured from a clean-catch urine sample. We calculated sensitivity, specificity, and area under the receiver operator characteristic (AUROC) curve of coefficient-based (graded severity) and points-based (dichotomized) symptom/sign logistic regression models, and we then internally validated the AUROC using bootstrapping. RESULTS Three thousand thirty-six children provided urine samples, and culture results were available for 2,740 (90%). Of these results, 60 (2.2%) were positive: the clinical diagnosis was 46.6% sensitive, with an AUROC of 0.77. Previous UTI, increasing pain/crying on passing urine, increasingly smelly urine, absence of severe cough, increasing clinician impression of severe illness, abdominal tenderness on examination, and normal findings on ear examination were associated with UTI. The validated coefficient- and points-based model AUROCs were 0.87 and 0.86, respectively, increasing to 0.90 and 0.90, respectively, by adding dipstick nitrites, leukocytes, and blood. CONCLUSIONS A clinical rule based on symptoms and signs is superior to clinician diagnosis and performs well for identifying young children for noninvasive urine sampling. Dipstick results add further diagnostic value for empiric antibiotic treatment

Comparison of microbiological diagnosis of urinary tract infection in young children by routine health service laboratories and a research laboratory: Diagnostic cohort study

OBJECTIVES: To compare the validity of diagnosis of urinary tract infection (UTI) through urine culture between samples processed in routine health service laboratories and those processed in a research laboratory. POPULATION AND METHODS: We conducted a prospective diagnostic cohort study in 4808 acutely ill children aged <5 years attending UK primary health care. UTI, defined as pure/predominant growth ≥105 CFU/mL of a uropathogen (the reference standard), was diagnosed at routine health service laboratories and a central research laboratory by culture of urine samples. We calculated areas under the receiver-operator curve (AUC) for UTI predicted by pre-specified symptoms, signs and dipstick test results (the "index test"), separately according to whether samples were obtained by clean catch or nappy (diaper) pads. RESULTS: 251 (5.2%) and 88 (1.8%) children were classified as UTI positive by health service and research laboratories respectively. Agreement between laboratories was moderate (kappa = 0.36; 95% confidence interval [CI] 0.29, 0.43), and better for clean catch (0.54; 0.45, 0.63) than nappy pad samples (0.20; 0.12, 0.28). In clean catch samples, the AUC was lower for health service laboratories (AUC = 0.75; 95% CI 0.69, 0.80) than the research laboratory (0.86; 0.79, 0.92). Values of AUC were lower in nappy pad samples (0.65 [0.61, 0.70] and 0.79 [0.70, 0.88] for health service and research laboratory positivity, respectively) than clean catch samples. CONCLUSIONS: The agreement of microbiological diagnosis of UTI comparing routine health service laboratories with a research laboratory was moderate for clean catch samples and poor for nappy pad samples and reliability is lower for nappy pad than for clean catch samples. Positive results from the research laboratory appear more likely to reflect real UTIs than those from routine health service laboratories, many of which (particularly from nappy pad samples) could be due to contamination. Health service laboratories should consider adopting procedures used in the research laboratory for paediatric urine samples. Primary care clinicians should try to obtain clean catch samples, even in very young children

The Diagnosis of Urinary Tract infection in Young children (DUTY): a diagnostic prospective observational study to derive and validate a clinical algorithm for the diagnosis of urinary tract infection in children presenting to primary care with an acute illness

Background: It is not clear which young children presenting acutely unwell to primary care should be investigated for urinary tract infection (UTI) and whether or not dipstick testing should be used to inform antibiotic treatment.Objectives: To develop algorithms to accurately identify pre-school children in whom urine should be obtained; assess whether or not dipstick urinalysis provides additional diagnostic information; and model algorithm cost-effectiveness.Design: Multicentre, prospective diagnostic cohort study.Setting and participants: Children &lt; 5 years old presenting to primary care with an acute illness and/or new urinary symptoms.Methods: One hundred and seven clinical characteristics (index tests) were recorded from the child’s past medical history, symptoms, physical examination signs and urine dipstick test. Prior to dipstick results clinician opinion of UTI likelihood (‘clinical diagnosis’) and urine sampling and treatment intentions (‘clinical judgement’) were recorded. All index tests were measured blind to the reference standard, defined as a pure or predominant uropathogen cultured at ? 105 colony-forming units (CFU)/ml in a single research laboratory. Urine was collected by clean catch (preferred) or nappy pad. Index tests were sequentially evaluated in two groups, stratified by urine collection method: parent-reported symptoms with clinician-reported signs, and urine dipstick results. Diagnostic accuracy was quantified using area under receiver operating characteristic curve (AUROC) with 95% confidence interval (CI) and bootstrap-validated AUROC, and compared with the ‘clinician diagnosis’ AUROC. Decision-analytic models were used toidentify optimal urine sampling strategy compared with ‘clinical judgement’.Results: A total of 7163 children were recruited, of whom 50% were female and 49% were &lt; 2 years old. Culture results were available for 5017 (70%); 2740 children provided clean-catch samples, 94% of whom were ? 2 years old, with 2.2% meeting the UTI definition. Among these, ‘clinical diagnosis’ correctly identified 46.6% of positive cultures, with 94.7% specificity and an AUROC of 0.77 (95% CI 0.71 to 0.83). Four symptoms, three signs and three dipstick results were independently associated with UTI with an AUROC (95% CI; bootstrap-validated AUROC) of 0.89 (0.85 to 0.95; validated 0.88) for symptoms and signs, increasing to 0.93 (0.90 to 0.97; validated 0.90) with dipstick results. Nappy pad samples were provided from the other 2277 children, of whom 82% were &lt; 2 years old and 1.3% met the UTI definition.‘Clinical diagnosis’ correctly identified 13.3% positive cultures, with 98.5% specificity and an AUROC of 0.63 (95% CI 0.53 to 0.72). Four symptoms and two dipstick results were independently associated with UTI, with an AUROC of 0.81 (0.72 to 0.90; validated 0.78) for symptoms, increasing to 0.87 (0.80 to 0.94; validated 0.82) with the dipstick findings. A high specificity threshold for the clean-catch model was more accurate and less costly than, and as effective as, clinical judgement. The additional diagnostic utility of dipstick testing was offset by its costs. The cost-effectiveness of the nappy pad model was not clear-cut.Conclusions: Clinicians should prioritise the use of clean-catch sampling as symptoms and signs can cost-effectively improve the identification of UTI in young children where clean catch is possible. Dipstick testing can improve targeting of antibiotic treatment, but at a higher cost than waiting for a laboratory result. Future research is needed to distinguish pathogens from contaminants, assess the impact of the clean-catch algorithm on patient outcomes, and the cost-effectiveness of presumptive versus dipstick versus laboratory-guided antibiotic treatment.Funding: The National Institute for Health Research Health Technology Assessment programme.<br/

Investigating the effectiveness and cost-effectiveness of FITNET-NHS (Fatigue In Teenagers on the interNET in the NHS) compared to Activity Management to treat paediatric chronic fatigue syndrome (CFS)/myalgic encephalomyelitis (ME):protocol for a randomised controlled trial

Background: Paediatric chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) is a relatively common and disabling condition. The National Institute for Health and Clinical Excellence (NICE) recommends Cognitive Behavioural Therapy (CBT) as a treatment option for paediatric CFS/ME because there is good evidence that it is effective. Despite this, most young people in the UK are unable to access local specialist CBT for CFS/ME. A randomised controlled trial (RCT) showed FITNET was effective in the Netherlands but we do not know if it is effective in the National Health Service (NHS) or if it is cost-effective. This trial will investigate whether FITNET-NHS is clinically effective and cost-effective in the NHS. Methods: Seven hundred and thirty-four paediatric patients (aged 11-17 years) with CFS/ ME will be randomised (1:1) to receive either FITNET-NHS (online CBT) or Activity Management (delivered via video call). The internal pilot study will use integrated qualitative methods to examine the feasibility of recruitment and the acceptability of treatment. The full trial will assess whether FITNET-NHS is clinically effective and cost-effective. The primary outcome is disability at 6 months, measured using the SF-36-PFS (Physical Function Scale) questionnaire. Cost-effectiveness is measured via cost-utility analysis from an NHS perspective. Secondary subgroup analysis will investigate the effectiveness of FITNET-NHS in those with co-morbid mood disorders. Discussion: If FITNET-NHS is found to be feasible and acceptable (internal pilot) and effective and cost-effective (full trial), its provision by the NHS has the potential to deliver substantial health gains for the large number of young people suffering from CFS/ME but unable to access treatment because there is no local specialist service. This trial will provide further evidence evaluating the delivery of online CBT to young people with chronic conditions