Thyroid function changes and cytokine alterations following major surgery

To establish whether cytokine release is implicated in thyroid hormone changes during surgical stress we studied 36 adult patients (20 men; mean age +/- SD: 68.5 +/- 10.5 years) undergoing elective major abdominal operations. We measured tumor necrosis factor (TNF)-alpha, interleukin (IL)-6, IL-8 and IL-10 and thyrotropin (TSH), free thyroxine (FT 4) and triiodothyronine (T 3) before scheduled non-emergency surgery, immediately postoperatively, on the 1st postoperative day (post-1) and on the 2nd postoperative day (post-2). TNF alpha, IL-6 and IL-8 peaked on day post-1 whereas IL-10 peaked immediately postoperatively. Fourteen of 36 patients had low T 3 levels after surgery, indicating non-thyroidal illness (NTI). Significant negative correlations were noted among TNF-alpha, IL-6 and IL-8 against T-3 and FT4. Cytokines are responsible, at least in part, for NTI following major operations. Copyright (c) 2007 S. Karger AG, Basel

Post-Traumatic Stress Disorder and Burnout in Healthcare Professionals During the SARS-CoV-2 Pandemic: A Cross-Sectional Study

Healthcare professionals who are directly involved in the diagnosis, treatment, and general care of patients with SARS-CoV-2 are at risk of developing adverse psychological reactions. A cross-sectional study of healthcare professionals aimed to determine the impact of the SARS-CoV-2 pandemic on the mental health of healthcare professionals in two of the largest referral hospitals in Athens, Greece

Post-Traumatic Stress Disorder and Burnout in Healthcare Professionals During the SARS-CoV-2 Pandemic: A Cross-Sectional Study

Introduction: Healthcare professionals who are directly involved in the diagnosis, treatment, and general care of patients with SARS-CoV-2 are at risk of developing adverse psychological reactions. A cross-sectional study of healthcare professionals aimed to determine the impact of the SARS-CoV-2 pandemic on the mental health of healthcare professionals in two of the largest referral hospitals in Athens, Greece. Methods: The study was conducted in the two largest SARS-CoV-2 referral hospitals in Athens, Greece. An assessment and the interrelationship of post-traumatic stress disorder, using the Impact of Event Scale-Revised [IES-R]) and burnout, using the Maslach Burnout Inventory [MBI]) was carried out. Results: A total of 162 subjects were enrolled in the study. Fifty-six (35%) had an IES-R score > 33, suggesting post-traumatic stress disorder. Forty-nine (30%) had an MBI score > 27. Seventy-five (46%) had a personal accomplishment score of < 33 and 46 (28%) had a depersonalization score >10. Stepwise backward logistic regression revealed that the only independent variable that was retained regarding the presence of post-traumatic stress disorder was the emotional exhaustion score of the MBI (at a cut-off of 24 in this scale, the 95% CI of the odds ratio for the presence of post-traumatic stress disorder was 1.077-1.173). Conclusions: In this sample of first-line Greek healthcare professionals against SARS-CoV-2, most of them were proven to be quite resilient to this challenge. One-third of them had post-traumatic stress disorder, which depended on their degree of emotional exhaustion. Healthcare professionals, as represented by this study, performed their duties without feeling helpless and developing adverse psychological reactions

Αερικό θεραπευτήριο

Περίληψη: Η παρούσα διπλωματική εργασία αποτελεί μία προσπάθεια μεταγραφής των αρχαίων Ασκληπιείων και εγγραφής τους στον αστικό ιστό της Αθήνας. Στα Ασκληπιεία η ασθένεια θεωρείτο ως ένα αποτέλεσμα πολύπλοκων και αρνητικών αλληλεπιδράσεων (περιβαλλοντικών, κοινωνικών, ψυχολογικών, πνευματικών, συναισθηματικών και φυσικών παραγόντων) και η φροντίδα υγείας φαίνεται να στόχευε στην εξομάλυνση των συγκρούσεων και στην αποκατάσταση της αρμονίας του ασθενή, έχοντας ως επικουρική βοήθεια την ιατρική. Με βάση τα παραπάνω, επεμβαίνουμε στην περιοχή Κουντουριώτικα με τη δημιουργία μιας ευέλικτης κτιριακής δομής, που φιλοξενεί δημόσια λουτρά και ολοκληρώνεται διαμορφώνοντας έναν "θεραπευτικό" περίπατο μεταξύ πόλης και τοπίου, αναρριχώμενο στο λόφο του Λυκαβηττού και γινόμενο ένα με τη φύση