8 research outputs found

    Desvendando as percepções e práticas adotadas pelos pesquisadores dos programas de pós-graduação em Ecologia do nodeste brasileiro na gestão dos dados científicos

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    Based on the premise that data from scientific investigations are usually stored on the researchers’ computers, discarded or even lost when the results are published in articles, making it impossible to produce new investigations, the present study sought to uncover the perceptions and practices adopted by the researchers from the postgraduation programs of of the brazilian northeast ecology in the management of scientific data, based on the emerging national and international phenomenon, e-Science, that transformed the way research data can be produced, disseminated, managed, shared and reused taking start at the data curation process. In the view of the above, the researchers from the postgraduation programs of the brazilian northeast ecology were questioned about the perceptions and practices adopted in the management of scientific data. This study is an exploratory research, that aims to increase the knowledge about the subject, and a qualitative and quantitative approach to analyze the data that were collected through the application of a questionnaire. It was concluded that the reality of data sharing through the proccess of curatorship is emerging, since some of the subjects of this research already use tools that help with the data management plan, and others have a great interest in increasing their knowledge about the practices of management of scientific data for later sharing.NenhumaBaseado na premissa de que os dados oriundos de investigações científicas costumam ficar armazenados nos computadores pessoais dos pesquisadores, ou são descartados e perdidos após a publicação dos resultados em artigos, impossibilitando a produção de novas investigações, este estudo buscou desvendar as percepções e práticas adotadas pelos pesquisadores dos Programas de Pós-Graduação em Ecologia do Nordeste Brasileiro na gestão dos dados científicos, baseando-se no fenômeno emergente nacional e internacionalmente, e-Science, que transformou a forma como os dados de pesquisa podem ser produzidos, disseminados, gerenciados, compartilhados e (re) utilizados a partir do processo de curadoria dos dados. Diante do exposto, indagou-se quais as percepções e práticas adotadas pelos pesquisadores dos Programas de Pós-Graduação em Ecologia do nordeste brasileiro na gestão de dados científicos. Trata-se de uma pesquisa exploratória, visando a ampliação do conhecimento acerca do tema, e de abordagem qualitativa e quantitativa para análise dos dados que foram coletados por meio da aplicação de um questionário. Concluímos que a realidade do compartilhamento de dados por meio do processo de curadoria dos mesmos é emergente, visto que alguns dos sujeitos desta pesquisa já utilizam ferramentas que auxiliam no plano de gestão de dados, e outros, tem imenso interesse em aumentar seus conhecimentos, em relação às práticas de gestão de dados científicos para posterior compartilhamento

    A gestão dos dados de pesquisa no âmbito da comunidade dos pesquisadores vinculados aos programas de pós graduação brasileiros na área da Ciência da Informação: desvendando as práticas e percepções associadas ao uso e reuso de dados dados

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    The research investigated the practices and perceptions associated with data management by researchers in Brazilian postgraduate programs in the Information Science (IC) area. A semi-structured survey was used as the research instrument, it was sent by e-mail to 341 researchers linked to the Brazilian postgraduate programs in CI. The data was analyzed through descriptive statistics techniques and thematic analysis. It was found that the data management practices conducted by the researchers need to be improved and that they have a favorable approach regarding data sharing, provided there is some formal control over them

    Síndrome de Allgrove e amiotrofia: uma associação rara

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    A Síndrome de Allgrove é uma doença rara hereditária, causada por mutações no gene AAAS, que possui uma tríade clássica de sintomas caracterizada por alacrimia, acalasia e insuficiência adrenal. Além da tríade, sinais neurológicos como disfunção autonômica, microcefalia, disfunção cognitiva ou demência leve, doença do neurônio motor/amiotrofia e outros podem ser mencionados em até 70% dos casos. Nessa perspectiva, o objetivo desse trabalho é a realização de um estudo observacional e exploratório sobre os artigos publicados nos últimos 5 anos sobre associação rara entre a síndrome de allgrove e amiotrofia, uma vez que essa é uma comorbidade rara da síndrome. Dos 140 resultados obtidos na pesquisa, apenas 9 abordaram de forma objetiva sobre o tema, sendo utilizados na confecção do estudo. Segundo a literatura, a amiotrofia é uma comorbidade rara da síndrome de Allgrove, que possui grande relevância devido ao seu curso rápido e progressivo

    Adopting the Dublin Core Standard for Describing Open Scientific Data: The e-Quilt Prototype Experiment

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    This research contextualizes the contemporary state of the scientific communication. The technological infrastructure, standards, protocols, tools, and methodologies are essential for scientific open data management. Our focus is on the scientific primary data and its sharing. It presents a experiment in which the prototype, named e-Quilt, is being developed. In its environment, an enhanced article and the scientific open data are presented. The research aims at adopting an infrastructure with standard and tool for upgrading the e-Quilt prototype. The adopted metadata standard was the Dublin Core. The technique was qualitative used for the independent and dependent variables. The analyze was focusing in the adequacy of the e-Quilt prototype in accordingly with the standard. The results presented that the enhanced article is complies with the Dublin Core standard

    O26 Polysaccharides as Key Players in Enteropathogenic <i>E. coli</i> Immune Evasion and Vaccine Development

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    Enteropathogenic Escherichia coli (EPEC) produce a capsule of polysaccharides identical to those composing the O-antigen polysaccharide of its LPS (lipopolysaccharide) molecules. In light of this, the impact of O26 polysaccharides on the immune evasion mechanisms of capsulated O26 EPEC compared to non-capsulated enterohemorrhagic Escherichia coli (EHEC) was investigated. Our findings reveal that there was no significant difference between the levels in EPEC and EHEC of rhamnose (2.8:2.5), a molecule considered to be a PAMP (Pathogen Associated Molecular Patterns). However, the levels of glucose (10:1.69), heptose (3.6:0.89) and N-acetylglucosamine (4.5:2.10), were significantly higher in EPEC than EHEC, respectively. It was also observed that the presence of a capsule in EPEC inhibited the deposition of C3b on the bacterial surface and protected the pathogen against lysis by the complement system. In addition, the presence of a capsule also protected EPEC against phagocytosis by macrophages. However, the immune evasion provided by the capsule was overcome in the presence of anti-O26 polysaccharide antibodies, and additionally, these antibodies were able to inhibit O26 EPEC adhesion to human epithelial cells. Finally, the results indicate that O26 polysaccharides can generate an effective humoral immune response, making them promising antigens for the development of a vaccine against capsulated O26 E. coli.</i

    ATLANTIC ANTS: a data set of ants in Atlantic Forests of South America

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