Balancing Surface Energy Terms for Stable Growth of Planar Surfaces

We investigate the driving forces that determine the growth mode of heteroepitaxial Ge layers grown from solution on Si substrates with orientations (001), (011) and (111) by transmission electron microscopy (TEM) and atomic force microscopy (AFM). Using liquid phase epitaxy, we can study the influences of strain and surface energy terms independently on effects due to limited surface diffusion. In (001) and (011) orientated layers, {111} faceted islands form (Stranski-Krastanov growth). In contrast, (111) orientated layers grow in a two-dimensional step flow growth mode (Frank-van der Merwe growth). We model these investigations in terms of energy minimisation considering surface energy reduction by formation of faceted islands and elastic strain energy relaxation by island formation. The strain energy relaxation by island formation is calculated by the finite element method. According to our considerations, two-dimensional growth is obtained by selective increase of the free surface energy of the low indices facet planes to a value higher than that of the substrate surface. Formation of faceted islands thus would increase the total surface energy; as a consequence, island formation is suppressed. By choosing the appropriate solvent and temperature in solution growth, we can provide for thermodynamically stable two-dimensional growth

Razor clam to RoboClam: burrowing drag reduction mechanisms and their robotic adaptation

Estimates based on the strength, size, and shape of the Atlantic razor clam (Ensis directus) indicate that the animal's burrow depth should be physically limited to a few centimeters; yet razor clams can dig as deep as 70 cm. By measuring soil deformations around burrowing E. directus, we have found the animal reduces drag by contracting its valves to initially fail, and then fluidize, the surrounding substrate. The characteristic contraction time to achieve fluidization can be calculated directly from soil properties. The geometry of the fluidized zone is dictated by two commonly-measured geotechnical parameters: coefficient of lateral earth pressure and friction angle. Calculations using full ranges for both parameters indicate that the fluidized zone is a local effect, occurring between 1–5 body radii away from the animal. The energy associated with motion through fluidized substrate—characterized by a depth-independent density and viscosity—scales linearly with depth. In contrast, moving through static soil requires energy that scales with depth squared. For E. directus, this translates to a 10X reduction in the energy required to reach observed burrow depths. For engineers, localized fluidization offers a mechanically simple and purely kinematic method to dramatically reduce energy costs associated with digging. This concept is demonstrated with RoboClam, an E. directus-inspired robot. Using a genetic algorithm to find optimal digging kinematics, RoboClam has achieved localized fluidization burrowing performance comparable to that of the animal, with a linear energy-depth relationship, in both idealized granular glass beads and E. directus' native cohesive mudflat habitat.Battelle Memorial InstituteBluefin RoboticsChevron Corporatio

Multi-Substrate Burrowing Performance and Constitutive Modeling of RoboClam: A Biomimetic Robot Based on Razor Clams

The Atlantic razor clam (Ensis directus) reduces burrowing drag by using motions of its shell to fluidize a thin layer of substrate around its body. We have developed RoboClam, a robot that digs using the same mechanisms as Ensis, to explore how localized fluidization burrowing can be extended to engineering applications. In this work we present burrowing performance results of RoboClam in two distinctly different substrates: ideally granular 1mm soda lime glass beads and cohesive ocean mudflat soil. Using a genetic algorithm to optimize RoboClam’s kinematics, the machine was able to burrow in both substrates with a power law relationship between digging energy and depth of n = 1.17. Pushing through static soil has a theoretical energy-depth power law of n = 2, which means that Ensis-inspired burrowing motions can provide exponentially higher energy efficiency. We propose a theoretical constitutive model that describes how a fluidized region should form around a contracting body in virtually any type of saturated soil. The model predicts fluidization to be a relatively local effect, extending only two to three characteristic lengths away from the body, depending on friction angle and coefficient of lateral earth pressure, two commonly measured soil parameters.Battelle Memorial InstituteBluefin RoboticsChevron Corporatio

Sub-stellar companions of intermediate-mass stars with CoRoT: CoRoT–34b, CoRoT–35b, and CoRoT–36b

Theories of planet formation give contradicting results of how frequent close-in giant planets of intermediate mass stars (IMSs; 1.3≤M⋆≤3.2M⊙⁠) are. Some theories predict a high rate of IMSs with close-in gas giants, while others predict a very low rate. Thus, determining the frequency of close-in giant planets of IMSs is an important test for theories of planet formation. We use the CoRoT survey to determine the absolute frequency of IMSs that harbour at least one close-in giant planet and compare it to that of solar-like stars. The CoRoT transit survey is ideal for this purpose, because of its completeness for gas-giant planets with orbital periods of less than 10 d and its large sample of main-sequence IMSs. We present a high precision radial velocity follow-up programme and conclude on 17 promising transit candidates of IMSs, observed with CoRoT. We report the detection of CoRoT–34b, a brown dwarf close to the hydrogen burning limit, orbiting a 1.1 Gyr A-type main-sequence star. We also confirm two inflated giant planets, CoRoT–35b, part of a possible planetary system around a metal-poor star, and CoRoT–36b on a misaligned orbit. We find that 0.12±0.10 per cent of IMSs between 1.3≤M⋆≤1.6M⊙ observed by CoRoT do harbour at least one close-in giant planet. This is significantly lower than the frequency (⁠0.70±0.16 per cent⁠) for solar-mass stars, as well as the frequency of IMSs harbouring long-period planets (⁠∼8 per cent⁠)

Understanding the Behaviours Employed by Parents to Support the Psychological Development of Elite Youth Tennis Players in England

The current study had two objectives: (1) to explore which psychological skills (e.g., self-talk and imagery) and characteristics (e.g., motivation and focus) (PSCs) parents deemed important for their children’s development, and (2) to investigate and understand the parental behaviours that supported the growth or development of these PSCs. A nine-month qualitative study comprising observations of and semi-structured interviews with 15 parents of 11 British male elite youth tennis players (8-15 years of age) took place. Results suggested that parents were sceptical of the development of psychological skills due to (1) a perceived inability to support the development effectively, (2) a misconception of psychological skills, and (3) concerns about unnecessary pressure. Despite this, parents reported the use of four behaviours in an effort to develop psychological characteristics within their children, including (1) talking about valuable psychological characteristics, (2) intentionally creating learning opportunities, (3) enabling athletes to go the extra mile, and (4) fostering developmentally beneficial peer relationships. Although well intended, these behaviours were usually informed by intermittent self-education, sometimes resulting in unwanted consequences such as the establishment of performance orientated climates. The results of this study add to the youth sport literature by providing insight into sport parents’ perceptions of PSCs, as well as the behaviours they employed to support their children’s psychological development. Additionally, it reinforces the need for more formalised parental education opportunities to support parents’ positive involvement in their children’s sporting lives

PT-symmetric noncommutative spaces with minimal volume uncertainty relations

We provide a systematic procedure to relate a three dimensional q-deformed oscillator algebra to the corresponding algebra satisfied by canonical variables describing noncommutative spaces. The large number of possible free parameters in these calculations is reduced to a manageable amount by imposing various different versions of PT-symmetry on the underlying spaces, which are dictated by the specific physical problem under consideration. The representations for the corresponding operators are in general non-Hermitian with regard to standard inner products and obey algebras whose uncertainty relations lead to minimal length, areas or volumes in phase space. We analyze in particular one three dimensional solution which may be decomposed to a two dimensional noncommutative space plus one commuting space component and also into a one dimensional noncommutative space plus two commuting space components. We study some explicit models on these type of noncommutative spaces.Comment: 18 page

Multi-omics integration identifies key upstream regulators of pathomechanisms in hypertrophic cardiomyopathy due to truncating MYBPC3 mutations

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is the most common genetic disease of the cardiac muscle, frequently caused by mutations in MYBPC3. However, little is known about the upstream pathways and key regulators causing the disease. Therefore, we employed a multi-omics approach to study the pathomechanisms underlying HCM comparing patient hearts harboring MYBPC3 mutations to control hearts. RESULTS: Using H3K27ac ChIP-seq and RNA-seq we obtained 9310 differentially acetylated regions and 2033 differentially expressed genes, respectively, between 13 HCM and 10 control hearts. We obtained 441 differentially expressed proteins between 11 HCM and 8 control hearts using proteomics. By integrating multi-omics datasets, we identified a set of DNA regions and genes that differentiate HCM from control hearts and 53 protein-coding genes as the major contributors. This comprehensive analysis consistently points toward altered extracellular matrix formation, muscle contraction, and metabolism. Therefore, we studied enriched transcription factor (TF) binding motifs and identified 9 motif-encoded TFs, including KLF15, ETV4, AR, CLOCK, ETS2, GATA5, MEIS1, RXRA, and ZFX. Selected candidates were examined in stem cell-derived cardiomyocytes with and without mutated MYBPC3. Furthermore, we observed an abundance of acetylation signals and transcripts derived from cardiomyocytes compared to non-myocyte populations. CONCLUSIONS: By integrating histone acetylome, transcriptome, and proteome profiles, we identified major effector genes and protein networks that drive the pathological changes in HCM with mutated MYBPC3. Our work identifies 38 highly affected protein-coding genes as potential plasma HCM biomarkers and 9 TFs as potential upstream regulators of these pathomechanisms that may serve as possible therapeutic targets