Neurofibromatosis type 2 (NF 2) or schwannomatosis? – Case report study and diagnostic criteria

Introduction Neurofibromatosis type 2 (NF2) and schwannomatosis are entities that may, due to the similarity of clinical symptoms, cause diagnostic difficulties. Incidence rate of both diseases is similar and estimated between 1:25,000 and 1:40,000. The genes associated with the development of the aforementioned disorders are located on chromosome 22 and lay in proxmity. Schwannomatosis is characterized by an incomplete penetrance and the risk of its transmission to the offspring is significantly lower than in the case of NF 2. Schwannomatosis clinical characteristic is similar to the NF2, however vestibular schwannomas are not present. Therefore the imaging studies evaluated by an experienced radiologist play a key role in the diagnostic process. Case report Forty two-year-old female hospitalized three times because of the tumors of the spinal canal was admitted to the Department of Neurosurgery and Peripheral Nerve Surgery in 2008 because of the cervical pain syndrome with concomitant headache. She was diagnosed with a schwannomatosis, recently distinguished, the third form of neurofibromatosis. MRI imaging revealed craniocervical junction tumor. Suboccipital craniectomy with concomitant C1–C2 laminectomy was done in order to remove the lesion. After the surgery the patient did not present any deficits in neurological examination and was discharged from hospital in good general condition. Conclusions The patient was diagnosed with schwannomatosis, recently established neurofibromatosis entity which may resemble NF2 clinically. In patients after the age of 30, in whom we observe multiple schwannomas without the concomitant hearing impairment, the diagnosis of schwannomatosis is very likely

Microbial biodiversity in arable soils is affected by agricultural practices

The aim of the study was to examine the differences in microbial community structure as a result of agricultural practices. Sixteen samples of cultivated and the same number of non-cultivated soils were selected. Gel bands were identified using the GelCompar software to create the presence-absence matrix, where each band represented a bacterial operational taxonomic unit. The data were used for principal-component analysis and additionally, the Shannon-Weaver index of general diversity, Simpson index of dominance and Simpson index of diversity were calculated. Denaturing gradient gel electrophoresis profiles clearly indicated differentiation of tested samples into two clusters: cultivated and non-cultivated soils. Greater numbers of dominant operational taxonomic units (65) in non-cultivated soils were noted compared to cultivated soils (47 operational taxonomic units). This implies that there was a reduction of dominant bacterial operational taxonomic units by nearly 30% in cultivated soils. Simpson dominance index expressing the number of species weighted by their abundance amounted to 1.22 in cultivated soils, whereas a 3-fold higher value (3.38) was observed in non-cultivated soils. Land-use practices seemed to be a important factors affected on biodiversity, because more than soil type determined the clustering into groups

Strategic insights : navigating business intelligence implementation : phases, tasks, and risks : a case study on an international manufacturing company

PURPOSE: This article aims to present a comprehensive case study of implementing a business intelligence system in the manufacturing company. Therefore, a comprehensive understanding of key implementation aspects and associated risks is vital for meticulous planning before investing in information systems.DESIGN/METHODOLOGY/APPROACH: Through qualitative research, the study will identify the main implementation phases, assign key tasks, and highlight the potential risks encountered during the process. By examining the case study, readers can gain insights into the effective implementation of a business intelligence system in manufacturing company, enabling them to better navigate similar ventures a significant input for researchers to create an implementation model.FINDINGS: Having accurate and timely information is a crucial asset for businesses, influencing their competitive advantage. Information is essential for decision-making, enabling organizations to identify opportunities, threats, strengths, weaknesses, and changes. Business Intelligence (BI) solutions cater to these needs by automatically transforming data into actionable information. However, due to the wide array of tools available in the market, the implementation process of BI can be complex.PRACTICAL IMPLICATIONS: The findings from this article's case study can serve as a foundation for proposing an implementation model for business intelligence systems.ORIGINALITY/VALUE: By analyzing the challenges, key phases, and risks identified in the case study, future research can develop a structured framework or model that outlines the necessary steps, considerations, and best practices for implementing BI systems specifically tailored to manufacturing industries.peer-reviewe

Actinobacteria Structure in Autogenic, Hydrogenic and Lithogenic Cultivated and Non-Cultivated Soils: A Culture-Independent Approach

The aim of the study was to determine the Actinobacteria structure in cultivated (C) versus non-cultivated (NC) soils divided into three groups (autogenic, hydrogenic, lithogenic) with consideration its formation process in order to assess the Actinobacteria sensitivity to agricultural soil use and soil genesis and to identify factors affecting their abundance. Sixteen C soil samples and sixteen NC samples serving as controls were taken for the study. Next generation sequencing (NGS) of the 16S rRNA metagenomic amplicons (Ion Torrent™ technology) and Denaturing Gradient Gel Electrophoresis (DGGE) were applied for precise determination of biodiversity. Generally, greater abundance of Actinobacteria in the NC soils relative to the C soils was found. Moreover, it was indicated that the actinobacterial diversity depended on both the soil genesis and the land use; however, this effect directly depended on the particular family and genera. Two factors: redox potential (Eh) and total carbon (TC) seemed to had a significant effect on the diversity of Actinobacteria. More precisely, Actinobacteria from the NC soils displayed a greater affinity for each other and were clearly influenced by Eh, whilst those from the C soils were mostly influenced by T

Teachers studying towards their own time budget

Pierwszy rozdział przybliża określenie czasu w różnych aspektach m.in. filozoficznym, psychologicznym, społecznym. Daje możliwość poznania definicji głównego pojęcia związanego z niniejszą pracą, jakim jest budżet czasu. A także przedstawia stan dotychczasowych badań nad budżetem czasu.Rozdział drugi zawiera metodologię badań własnych. Cel: zbadanie budżetu czasu nauczyciela studiującego. Problem główny: Jak przedstawia się budżet czasu nauczyciela studiującego w jego świadomości? A także problemy szczegółowe: Jaki jest budżet czasu nauczyciela studiującego, oraz co nauczyciele myślą o swoim budżecie czasu. Badania zostały przeprowadzone za pomocą następujących narzędzi badawczych: kwestionariusz ankiety i kwestionariusz wywiadu, którymi objęto 51 osobową grupę nauczycieli studiujących na wybranych uczelniach w Krakowie, oraz 44 osobową grupę nauczycieli niestudiujących, pracujących w Gminie Skawina.Przeprowadzony pomiar wykazał m.in., że tygodniowy budżet czasu nauczyciela przekracza tygodniowy czas zegarowy tj. 7x24, czyli 168 h. Zaspokajanie biologicznych potrzeb organizmu zajmuje największą część ich budżetu. Studiujący nauczyciele poświęcają się pracy w równym stopniu, co ich koledzy niestudiujący. Zdobywanie wykształcenia przez nauczycieli odbywa się kosztem, innych czynności mieszczących się w ich budżecie czasu.The first chapter introduces the timing in various aspects , among others, philosophical , psychological , social . It gives the opportunity to learn the definition of the main concepts associated with this work, which is the time budget . And also shows the status of current research budget time.The second chapter contains the research methodology of its own. Objective: To investigate the budget of the teacher's time studying . The main problem : What is the budget of the teacher's time studying in his mind ? As well as problems specific : What is the budget of the teacher's time studying , and what teachers think about their time budget . The research was conducted using the following research tools : questionnaire survey and interview questionnaire , which included a group of 51 teachers studying at selected universities in Krakow , and a group of 44 teachers who do not study and working in the Municipality of Skawina. Performed measurements showed among, other things that the teacher weekly time budget exceeds the weekly time of day , 7x24= 168 h. Address the biological needs of the body is the largest part of their budget. Teachers who study devote themselves to work in the same way, as their teachers who don’t study. Getting education by teachers at the expense of other activities within their time budget

Actinobacteria Structure in Autogenic, Hydrogenic and Lithogenic Cultivated and Non-Cultivated Soils: A Culture-Independent Approach

The aim of the study was to determine the Actinobacteria structure in cultivated (C) versus non-cultivated (NC) soils divided into three groups (autogenic, hydrogenic, lithogenic) with consideration its formation process in order to assess the Actinobacteria sensitivity to agricultural soil use and soil genesis and to identify factors affecting their abundance. Sixteen C soil samples and sixteen NC samples serving as controls were taken for the study. Next generation sequencing (NGS) of the 16S rRNA metagenomic amplicons (Ion Torrent™ technology) and Denaturing Gradient Gel Electrophoresis (DGGE) were applied for precise determination of biodiversity. Generally, greater abundance of Actinobacteria in the NC soils relative to the C soils was found. Moreover, it was indicated that the actinobacterial diversity depended on both the soil genesis and the land use; however, this effect directly depended on the particular family and genera. Two factors: redox potential (Eh) and total carbon (TC) seemed to had a significant effect on the diversity of Actinobacteria. More precisely, Actinobacteria from the NC soils displayed a greater affinity for each other and were clearly influenced by Eh, whilst those from the C soils were mostly influenced by TC