Aversive reaction between disulfiram and betel quid among inpatients with alcohol use disorder in Bhutan: A preliminary study

Betel Quid (BQ) is commonly used in the Asia-Pacific region. Disulfiram is prescribed for people with alcohol use disorders (PwAUDs) after the completion of detoxification as an alternative to rehabilitation. This prospective observational study reports the aversive reactions and common symptoms of Disulfiram and BQ in PwAUDs. Participants included PwAUDs admitted to the psychiatric ward at the Jigme Dorji Wangchuck National Referral Hospital for detoxification, who were on Disulfiram and using BQ at the same time. Aversive reactions between Disulfiram and BQ were observed for 100 patients over a year. Twenty participants showed aversive reactions between BQ and Disulfiram. Common symptoms included sweating, diarrhea, dizziness, tremors, palpitations, shortness of breath, nausea and vomiting, and headache. Since PwAUDs in Bhutan are inducted on Disulfiram after detoxification, and most use BQ simultaneously, this study will help inform health care providers to educate people about the aversive reactions of Disulfiram and BQ

Renewable Natural Resources (RNR)Research Programme in Bhutan : An Overview

The objective of this paper is to give an overview of how the Renewable Natural Resources (RNR) research is being implemented in Bhutan. The RNR sector comprises mainly of agriculture, livestock and forestry sectors. Agriculture research in Bhutan initially started in early 1960s through the introduction of new crop and fruit varieties from Indian Agriculture Research Institutes. Thereafter, livestock and forestry research started in livestock farms and forestry research institutes, respectively. The first Agriculture Research Institute in Bhutan was established in 1982 which underwent various changes culminating into the present Council for RNR Research of Bhutan (CoRRB) in 2003. The Council is chaired by the Minister of Agriculture and the Director of CoRRB functions as the member Secretary of the Council. Four research centres with national and regional mandates located at strategic locations of the country were established to cater to the research and development needs of the farmers living in different agro-ecological zones. These centres are mandated to carry out research in the field of agriculture, horticulture, livestock, forestry and other cross cutting sectors of soils, plant protection, water management, meteorology, socio-economic studies. Apart from the Regional centres of research, there are sub centres where ever the area to be covered by the centre is large. The different departments also conduct research in consultation with CoRRB to avoid duplication of efforts. The main objectives of the RNR Research are to generate relevant technologies for the farming communities for ensuring food security and enhancement of rural income. These technologies are packaged as extension materials,news letters and journals for dissemination to farmers and all concerned stakeholders.Article信州大学農学部紀要. 46(1-2): 139-153 (2010)departmental bulletin pape

The Fruit Flies (Diptera, Tephritidae) in Bhutan: New Faunistic Records and Compendium of Fauna

Based on a field survey from 2017, twenty-three species are reported from Bhutan for the first time: Acroceratitis ceratitina, A. hardyi, Anomoia approximata, Bactrocera connecta, B. latifrons, B. nigrifacia, B. syzygii, Campiglossa sororcula, Cecidochares connexa, Dacus jacobi, Gastrozona fasciventris, Hoplandromyia antelopa, Lenitovena ultima, Ptilona confinis, Rioxoptilona dunlopi, R. formosana, R. vaga, Spathulina acroleuca, Themara yunnana, Trypeta indica, Zeugodacus apiciflavus, Z. diversus, and Z. fereuncinatus. Four species of the genera Cornutrypeta, Hemilea, Morinowotome, and Vidalia are also recorded for the first time, but the precise determination to species needs additional study and material. As the result, 71 species is listed from Bhutan by far. Their taxonomic position and key characters are discussed. Illustrations for most of the newly recorded species are given

Educating Health Professionals about Disability: A Review of Interventions

Health professionals need to understand the human rights and health needs of disabled people. This review of evidence on interventions demonstrates that a range of often innovative approaches have been trialled. Lectures by faculty are less effective in changing attitudes than contact with disabled people themselves. Existing examples of good practice need to be scaled up, and better and more long-term evaluations of impact are required

Rabies virus strains circulating in Bhutan: implications for control.

postprintWe report a molecular epidemiological study of rabies virus strains circulating in animal populations in Bhutan, and investigate potential origins of these viruses. Twenty-three rabies virus isolates originating from dogs and other domestic animals were characterized by sequencing the partial nucleoprotein (N) gene (395 bp). Phylogenetic analysis was conducted and the Bhutanese isolates were compared with rabies viruses originating from other parts of the world. Phylogenetic analysis showed that Bhutanese isolates were highly similar and were closely related to Indian strains and South Asian Arctic–like–1 viruses. Our study suggests that the rabies viruses spreading in southern parts of Bhutan have originated from a common ancestor, perhaps from the Indian virus strain. Keywords: molecular epidemiology, rabies, Arctic–like virus, BhutanThailand Research Fund (grant No.DBG5180026

Rabies virus strains circulating in Bhutan: implications for control.

We report a molecular epidemiological study of rabies virus strains circulating in animal populations in Bhutan, and investigate potential origins of these viruses. Twenty-three rabies virus isolates originating from dogs and other domestic animals were characterized by sequencing the partial nucleoprotein (N) gene (395 bp). Phylogenetic analysis was conducted and the Bhutanese isolates were compared with rabies viruses originating from other parts of the world. Phylogenetic analysis showed that Bhutanese isolates were highly similar and were closely related to Indian strains and South Asian Arctic–like–1 viruses. Our study suggests that the rabies viruses spreading in southern parts of Bhutan have originated from a common ancestor, perhaps from the Indian virus strain. Keywords: molecular epidemiology, rabies, Arctic–like virus, BhutanThailand Research Fund (grant No.DBG5180026

Impact of COVID-19 on mental health in Bhutan: a way forward for action

The coronavirus disease 2019 (COVID-19) pandemic continues to impact mental health and wellbeing globally. There is a lack of scientific documentation highlighting the mental health impact of COVID-19 in Bhutan. We present the mental health burdens and control measures taken, and suggest ways to further strengthen mental health services in Bhutan. During the pandemic, a rise in depression and anxiety had been reported in Bhutan. Depression rose from an average prevalence of 9 per 10,000 between 2011 and 2019 to 16 per 10,000 in 2020 and 32 per 10,000 in 2021. Similarly, anxiety rose from an average prevalence of 18 per 10,000, to 29 per 10,000 in 2020, and 55 per 10,000 in 2021. Psychological impacts related to isolation due to lockdowns, economic losses, and poor coping abilities were associated with negative outcomes. Stigma and discrimination towards mental health disorders discouraged mentally distressed people from seeking care. In response to increased demand, Bhutan's government initiated a range of interventions including home delivery of medicines and tele-counselling to people in need of urgent mental health care. Mental health care in Bhutan can be further improved through investment in services and human resources, and decentralization of services to the community