Heavy quark free energies and screening at finite temperature and density

We study the free energies of heavy quarks calculated from Polyakov loop correlation functions in full 2-flavour QCD using the p4-improved staggered fermion action. A small but finite Baryon number density is included via Taylor expansion of the fermion determinant in the Baryo-chemical potential mu. For temperatures above Tc we extract Debye screening masses from the large distance behaviour of the free energies and compare their mu-dependence to perturbative results.Comment: 6 pages, Presented at 23rd International Symposium on Lattice Field Theory (Lattice 2005), Trinity College, Dublin, Ireland, 25-30 Jul 200

Engineering a plant community to deliver multiple ecosystem services

The sustainable delivery of multiple ecosystem services requires the management of functionally diverse biological communities. In an agricultural context, an emphasis on food production has often led to a loss of biodiversity to the detriment of other ecosystem services such as the maintenance of soil health and pest regulation. In scenarios where multiple species can be grown together, it may be possible to better balance environmental and agronomic services through the targeted selection of companion species. We used the case study of legume-based cover crops to engineer a plant community that delivered the optimal balance of six ecosystem services: early productivity, regrowth following mowing, weed suppression, support of invertebrates, soil fertility building (measured as yield of following crop), and conservation of nutrients in the soil. An experimental species pool of 12 cultivated legume species was screened for a range of functional traits and ecosystem services at five sites across a geographical gradient in the United Kingdom. All possible species combinations were then analyzed, using a process-based model of plant competition, to identify the community that delivered the best balance of services at each site. In our system, low to intermediate levels of species richness (one to four species) that exploited functional contrasts in growth habit and phenology were identified as being optimal. The optimal solution was determined largely by the number of species and functional diversity represented by the starting species pool, emphasizing the importance of the initial selection of species for the screening experiments. The approach of using relationships between functional traits and ecosystem services to design multifunctional biological communities has the potential to inform the design of agricultural systems that better balance agronomic and environmental services and meet the current objective of European agricultural policy to maintain viable food production in the context of the sustainable management of natural resources

Assessment of pulmonary antibodies with induced sputum and bronchoalveolar lavage induced by nasal vaccination against Pseudomonas aeruginosa: a clinical phase I/II study

<p>Abstract</p> <p>Background</p> <p>Vaccination against <it>Pseudomonas aeruginosa </it>is a desirable albeit challenging strategy for prevention of airway infection in patients with cystic fibrosis. We assessed the immunogenicity of a nasal vaccine based on the outer membrane proteins F and I from <it>Pseudomonas aeruginosa </it>in the lower airways in a phase I/II clinical trial.</p> <p>Methods</p> <p>N = 12 healthy volunteers received 2 nasal vaccinations with an OprF-OprI gel as a primary and a systemic (n = 6) or a nasal booster vaccination (n = 6). Antibodies were assessed in induced sputum (IS), bronchoalveolar lavage (BAL), and in serum.</p> <p>Results</p> <p>OprF-OprI-specific IgG and IgA antibodies were found in both BAL and IS at comparable rates, but differed in the predominant isotype. IgA antibodies in IS did not correlate to the respective serum levels. Pulmonary antibodies were detectable in all vaccinees even 1 year after the vaccination. The systemic booster group had higher IgG levels in serum. However, the nasal booster group had the better long-term response with bronchial antibodies of both isotypes.</p> <p>Conclusion</p> <p>The nasal OprF-OprI-vaccine induces a lasting antibody response at both, systemic and airway mucosal site. IS is a feasible method to non-invasively assess bronchial antibodies. A further optimization of the vaccination schedule is warranted.</p

Inspiring Farmers For Healthy Farming

"The health and nutritional value of agricultural food products is strongly linked to, and inherently dependent on the production process and farm system. However, there are currently only limited options for transferring and measuring farm-health principles at farm level (Vieweger and Döring, 2015). In our previous work we have shown how organic farmers have developed their own strategies and philosophies for running healthy farming systems and increase the health of soils, plants, animals and humans. Such tacit farmer knowledge and awareness of a holistic systems-approach to health in food production can contribute crucial information and practical understanding for food system sustainability. The current project builds on these earlier findings, using participatory multi-actor approaches to collaborate with the established international network. The farmer groups in Germany, Austria and the UK aimed to 1) conceptualize health criteria on farms, such as ‘Is a nutrient or humus balance calculated?‘, ‘How much time is spent for observation and reflection?’, ‘Are regionally adapted breeds and varieties used?’; and 2) develop a concept for farmer-to-farmer learning, defining most appropriate conditions and methodologies for the multiplication of this knowledge. With a co-learning approach, we aim to allow a flexible integration of farmer knowledge and experience, thereby inspiring farmers to reflect on the potential ways they can improve health in their system, and further develop their individual methods over time; this approach also aims to help research identify general drivers of farm health.

On the background in the γp→ω(π0γ)p\gamma p \to \omega(\pi^0\gamma) p reaction and mixed event simulation

In this paper we evaluate sources of background for the $\gamma p \to \omega p$, with the $\omega$ detected through its $\pi^0 \gamma$ decay channel, to compare with the experiment carried out at ELSA. We find background from $\gamma p \to \pi^0 \pi^0 p$ followed by decay of a $\pi^0$ into two $\gamma$, recombining one $\pi^0$ and one $\gamma$, and from the $\gamma p \to \pi^0 \eta p$ reaction with subsequent decay of the $\eta$ into two photons. This background accounts for the data at $\pi^0 \gamma$ invariant masses beyond 700 MeV, but strength is missing at lower invariant masses which was attributed to photon misidentification events, which we simulate to get a good reproduction of the experimental background. Once this is done, we perform an event mixing simulation to reproduce the calculated background and we find that the method provides a good description of the background at low $\pi^0 \gamma$ invariant masses but fakes the background at high invariant masses, making background events at low invariant masses, which are due to $\gamma$ misidentification events, responsible for the background at high invariant masses which is due to the $\gamma p \to \pi^0 \pi^0 p$ and $\gamma p \to \pi^0 \eta p$ reactions.Comment: 10 pages, 5 figure

Peptide transporter 2 (PEPT2) expression in brain protects against 5-aminolevulinic acid neurotoxicity

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65903/1/j.1471-4159.2007.04905.x.pd

Quantum Histories and Quantum Gravity

This paper reviews the histories approach to quantum mechanics. This discussion is then applied to theories of quantum gravity. It is argued that some of the quantum histories must approximate (in a suitable sense) to classical histories, if the correct classical regime is to be recovered. This observation has significance for the formulation of new theories (such as quantum gravity theories) as it puts a constraint on the kinematics, if the quantum/classical correspondence principle is to be preserved. Consequences for quantum gravity, particularly for Lorentz symmetry and the idea of "emergent geometry", are discussed.Comment: 35 pages (29 pages main body), two figure

The DNDN, πΣc\pi \Sigma_c interaction in finite volume and the Λc(2595)\Lambda_c(2595) resonance

In this work the interaction of the coupled channels $DN$ and $\pi \Sigma_c$ in an SU(4) extrapolation of the chiral unitary theory, where the $\Lambda_c(2595)$ resonance appears as dynamically generated from that interaction, is extended to produce results in finite volume. Energy levels in the finite box are evaluated and, assuming that they would correspond to lattice results, the inverse problem of determining the phase shifts in the infinite volume from the lattice results is solved. We observe that it is possible to obtain accurate $\pi \Sigma_c$ phase shifts and the position of the $\Lambda_c(2595)$ resonance, but it requires the explicit consideration of the two coupled channels. We also observe that some of the energy levels in the box are attached to the closed $DN$ channel, such that their use to induce the $\pi \Sigma_c$ phase shifts via L\"uscher's formula leads to incorrect results.Comment: 10 pages, 13 figures, accepted for publication in Eur. Phys. J.