99 research outputs found

    Level-Set Mass-Conservative Front-Tracking Technique for Multistep Simulations of In-Flight Ice Accretion

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    This paper presents a novel level-set-based approach to model evolving boundary problems for in-flight ice accretion. No partial differential equations are solved as in the standard level-set formulation, but simple geometrical quantities are employed to provide an implicit discretization of the updated boundary. This method avoids mesh entanglements and grid intersections typical of algebraic and mesh deforming techniques, making it suitable for generating a body-fitted discretization of arbitrarily complex geometries as in-flight ice shapes, including the collision of separate ice fronts. Moreover, this paper presents a local ice thickness correction, which accounts for the body's curvature, to conserve the prescribed iced mass locally. The verification includes ice accretion over an ellipse and a manufactured example to show the proposed strategy's advantages and robustness compared to standard algebraic methods. Finally, the method is applied to ice accretion problems. A temporal and grid convergence study is presented for automatic multistep in-flight simulations over a NACA0012 airfoil in rime, glaze, and mixed ice conditions

    La Favorita

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    De cada obra s'ha digitalitzat un programa sencer. De la resta s'han digitalitzat les parts que són diferents.Empresa Juan A. PamiasÒpera de Gaetano Donizetti i llibret de Royer i Wae

    Lucía de Lammermoor

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    Empresa Juan A. PamiasFunció a 'beneficio con bandeja a favor de los empleados permanentes, porteros y acomodadoresIntèrprets : Joan Sutherland , Jaume AragallOrquestra del Gran Teatre del Liceu dirigida per Gianfranco RivoliRegidor d'escena : Pablo Civil ; Mestre de Cor : Ricardo Bottino ; Mestre de ball : Joan Magrinyà ; Mestre apuntador : Àngel Anglad

    Adipose Tissue-Derived Stem Cell Treatment Prevents Renal Disease Progression

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    Adipose tissue-derived stem cells (ASCs) are an attractive source of stem cells with regenerative properties that are similar to those of bone marrow stem cells. Here, we analyze the role of ASCs in reducing the progression of kidney fibrosis. Progressive renal fibrosis was achieved by unilateral clamping of the renal pedicle in mice for 1 h; after that, the kidney was reperfused immediately. Four hours after the surgery, 2 x 10(5) ASCs were intraperitoneally administered, and mice were followed for 24 h posttreatment and then at some other time interval for the next 6 weeks. Also, animals were treated with 2 x 10(5) ASCs at 6 weeks after reperfusion and sacrificed 4 weeks later to study their effect when interstitial fibrosis is already present. At 24 h after reperfusion, ASC-treated animals showed reduced renal dysfunction and enhanced regenerative tubular processes. Renal mRNA expression of IL-6 and TNF was decreased in ASC-treated animals, whereas IL-4. IL-10, and HO-1 expression increased despite a lack of ASCs in the kidneys as determined by SRY analysis. As expected, untreated kidneys shrank at 6 weeks, whereas the kidneys of ASC-treated animals remained normal in size, showed less collagen deposition, and decreased staining for FSP-1, type I collagen, and Hypoxyprobe. the renal protection seen in ASC-treated animals was followed by reduced serum levels of TNF-alpha, KC, RANTES, and IL-1 alpha. Surprisingly, treatment with ASCs at 6 weeks, when animals already showed installed fibrosis, demonstrated amelioration of functional parameters, with less tissue fibrosis observed and reduced mRNA expression of type I collagen and vimentin. ASC therapy can improve functional parameters and reduce progression of renal fibrosis at early and later times after injury, mostly due to early modulation of the inflammatory response and to less hypoxia, thereby reducing the epithelial-mesenchymal transition.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)DECIT/Ministerio do SaudeComplex Fluids INCTUniversidade Federal de São Paulo, Div Nephrol, Escola Paulista Med, Expt & Clin Immunol Lab, BR-04023900 São Paulo, BrazilUniv São Paulo, Dept Pathol, São Paulo, BrazilUniv Fed Triangulo Mineiro, Div Pathol, Uberaba, MG, BrazilUniv São Paulo, Dept Immunol, Lab Transplantat Immunobiol, São Paulo, BrazilUniversidade Federal de São Paulo, Div Nephrol, Escola Paulista Med, Expt & Clin Immunol Lab, BR-04023900 São Paulo, BrazilFAPESP: 09/13251-6FAPESP: 07/07139-3CNPq: 473844/2009-5Web of Scienc

    La favorita

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    Empresa: Juan A. PamiasDe cada obra s'ha digitalitzat un programa sencer. De la resta s'han digitalitzat les parts que són diferents

    Ana Bolena

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    De cada obra s'ha digitalitzat un programa sencer. De la resta s'han digitalitzat les parts que són diferents.Empresa: Juan A. PamiasMestre de cor : Riccardo BottinoOrquestra del Gran Teatre del Liceu dirigida per CillarioÒpera de Donizetti i llibret de Roman

    Lucia di Lammermoor

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    Coreògraf i mestre de ball Joan MagrinyàDe cada obra s'ha digitalitzat un programa sencer. De la resta s'han digitalitzat les parts que són diferents.Empresa: Juan A. PamiasIntèrpret Luciano PavarottiOrquestra del Gran Teatre del Liceu dirigida per Franco FerrarisÒpera de Gaetano Donizetti i llibret de Salvatore Cammaran

    Lucrezia Borgia

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    Coreògraf i mestre de ball Joan MagrinyàDe cada obra s'ha digitalitzat un programa sencer. De la resta s'han digitalitzat les parts que són diferents.Empresa: Juan A. PamiasIntèrprets : Montserrat Caballé i Josep CarrerasOrquestra del Gran Teatre del Liceu dirigida per Reynald GiovaninettiÒpera de Gaetano Donizetti amb llibret de Felice Romani sobre una obra de Victor Hug
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