10 research outputs found

    Membrane targeted Azobenzene drives optical modulation of bacterial membrane potential

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    Recent studies have shown that bacterial membrane potential is dynamic and plays signaling roles. Yet, little is still known about the mechanisms of membrane potential dynamics regulation—owing to a scarcity of appropriate research tools. Optical modulation of bacterial membrane potential could fill this gap and provide a new approach for studying and controlling bacterial physiology and electrical signaling. Here, the authors show that a membrane-targeted azobenzene (Ziapin2) can be used to photo-modulate the membrane potential in cells of the Gram-positive bacterium Bacillus subtilis. It is found that upon exposure to blue–green light (λ = 470 nm), isomerization of Ziapin2 in the bacteria membrane induces hyperpolarization of the potential. To investigate the origin of this phenomenon, ion-channel-deletion strains and ion channel blockers are examined. The authors found that in presence of the chloride channel blocker idanyloxyacetic acid-94 (IAA-94) or in absence of KtrAB potassium transporter, the hyperpolarization response is attenuated. These results reveal that the Ziapin2 isomerization can induce ion channel opening in the bacterial membrane and suggest that Ziapin2 can be used for studying and controlling bacterial electrical signaling. This new optical tool could contribute to better understand various microbial phenomena, such as biofilm electric signaling and antimicrobial resistance

    MAGIC and H.E.S.S. detect VHE gamma rays from the blazar OT081 for the first time: a deep multiwavelength study

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    https://pos.sissa.it/395/815/pdfPublished versio

    Intensity interferometry with the MAGIC telescopes

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    Due to their large mirror size, fast response to single photons, sensitivity and telescope baselines in the order of 100 m, Imaging Atmospheric Cherenkov Telescopes are ideally suited to perform intensity interferometry observations. In 2019 a test readout setup was installed in the two 17-m diameter MAGIC telescopes to allow performing interferometry measurements with them. The first on-sky measurements were able to detect correlated intensity fluctuations consistent with the stellar diameters of three different stars: Adhara (n CMa), Benetnasch ([ UMa) and Mirzam (V CMa). After the upgrade of the setup in 2021, MAGIC is now equipped with a high-duty-cycle intensity interferometer, already in operation. A technical description of the interferometer and first performance results obtained by measuring several known stellar diameter are presented

    Extreme blazars under the eyes of MAGIC

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    Extreme high-frequency-peaked BL Lac objects (EHBLs) are the most energetic persistent sources in the universe. This contribution reports on long-term observing campaigns of tens of EHBLs that have been organized by the MAGIC collaboration to enlarge their population at VHE and understand the origin of their extreme properties. EHBLs are characterized by a spectral energy distribution (SED) featuring a synchrotron peak energy above 1 keV. Several EHBLs display a hard spectral index at very high energies (VHE; E > 100 GeV), suggesting a gamma-ray SED component peaking significantly above 1 TeV. Such extreme properties are challenging current standard emission and acceleration mechanisms. Recent studies have also unveiled intriguing disparities in the temporal characteristics of EHBLs. Some sources seem to display a persistent EHBL behaviour, while others belong to the EHBL family only temporarily. Here, we present recent results of the first hard-TeV EHBL catalog. The MAGIC observations are accompanied by an extensive multiwavelength coverage to obtain an optimal determination of the SED. This allow us to investigate leptonic and hadronic scenarios for the emission. We also present the recent detection of the EHBL RX J0812.0+0237 in the VHE band by MAGIC. Finally, we discuss a broad multiwavelength campaign on the BL Lac type object 1ES 2344+514, which showed intermittent EHBL characteristics in August 2016

    Multi-epoch monitoring of TXS 0506+056 with MAGIC and MWL partners

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    Chasing Gravitational Waves with the Chereknov Telescope Array

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    Presented at the 38th International Cosmic Ray Conference (ICRC 2023), 2023 (arXiv:2309.08219)2310.07413International audienceThe detection of gravitational waves from a binary neutron star merger by Advanced LIGO and Advanced Virgo (GW170817), along with the discovery of the electromagnetic counterparts of this gravitational wave event, ushered in a new era of multimessenger astronomy, providing the first direct evidence that BNS mergers are progenitors of short gamma-ray bursts (GRBs). Such events may also produce very-high-energy (VHE, > 100GeV) photons which have yet to be detected in coincidence with a gravitational wave signal. The Cherenkov Telescope Array (CTA) is a next-generation VHE observatory which aims to be indispensable in this search, with an unparalleled sensitivity and ability to slew anywhere on the sky within a few tens of seconds. New observing modes and follow-up strategies are being developed for CTA to rapidly cover localization areas of gravitational wave events that are typically larger than the CTA field of view. This work will evaluate and provide estimations on the expected number of of gravitational wave events that will be observable with CTA, considering both on- and off-axis emission. In addition, we will present and discuss the prospects of potential follow-up strategies with CTA

    Chasing Gravitational Waves with the Chereknov Telescope Array

    No full text
    Presented at the 38th International Cosmic Ray Conference (ICRC 2023), 2023 (arXiv:2309.08219)2310.07413International audienceThe detection of gravitational waves from a binary neutron star merger by Advanced LIGO and Advanced Virgo (GW170817), along with the discovery of the electromagnetic counterparts of this gravitational wave event, ushered in a new era of multimessenger astronomy, providing the first direct evidence that BNS mergers are progenitors of short gamma-ray bursts (GRBs). Such events may also produce very-high-energy (VHE, > 100GeV) photons which have yet to be detected in coincidence with a gravitational wave signal. The Cherenkov Telescope Array (CTA) is a next-generation VHE observatory which aims to be indispensable in this search, with an unparalleled sensitivity and ability to slew anywhere on the sky within a few tens of seconds. New observing modes and follow-up strategies are being developed for CTA to rapidly cover localization areas of gravitational wave events that are typically larger than the CTA field of view. This work will evaluate and provide estimations on the expected number of of gravitational wave events that will be observable with CTA, considering both on- and off-axis emission. In addition, we will present and discuss the prospects of potential follow-up strategies with CTA

    Chasing Gravitational Waves with the Chereknov Telescope Array

    No full text
    Presented at the 38th International Cosmic Ray Conference (ICRC 2023), 2023 (arXiv:2309.08219)2310.07413International audienceThe detection of gravitational waves from a binary neutron star merger by Advanced LIGO and Advanced Virgo (GW170817), along with the discovery of the electromagnetic counterparts of this gravitational wave event, ushered in a new era of multimessenger astronomy, providing the first direct evidence that BNS mergers are progenitors of short gamma-ray bursts (GRBs). Such events may also produce very-high-energy (VHE, > 100GeV) photons which have yet to be detected in coincidence with a gravitational wave signal. The Cherenkov Telescope Array (CTA) is a next-generation VHE observatory which aims to be indispensable in this search, with an unparalleled sensitivity and ability to slew anywhere on the sky within a few tens of seconds. New observing modes and follow-up strategies are being developed for CTA to rapidly cover localization areas of gravitational wave events that are typically larger than the CTA field of view. This work will evaluate and provide estimations on the expected number of of gravitational wave events that will be observable with CTA, considering both on- and off-axis emission. In addition, we will present and discuss the prospects of potential follow-up strategies with CTA

    Performance of a proposed event-type based analysis for the Cherenkov Telescope Array

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    The Cherenkov Telescope Array (CTA) will be the next-generation observatory in the field of very-high-energy (20 GeV to 300 TeV) gamma-ray astroparticle physics. Classically, data analysis in the field maximizes sensitivity by applying quality cuts on the data acquired. These cuts, optimized using Monte Carlo simulations, select higher quality events from the initial dataset. Subsequent steps of the analysis typically use the surviving events to calculate one set of instrument response functions (IRFs). An alternative approach is the use of event types, as implemented in experiments such as the Fermi-LAT. In this approach, events are divided into sub-samples based on their reconstruction quality, and a set of IRFs is calculated for each sub-sample. The sub-samples are then combined in a joint analysis, treating them as independent observations. This leads to an improvement in performance parameters such as sensitivity, angular and energy resolution. Data loss is reduced since lower quality events are included in the analysis as well, rather than discarded. In this study, machine learning methods will be used to classify events according to their expected angular reconstruction quality. We will report the impact on CTA high-level performance when applying such an event-type classification, compared to the classical procedure
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