192 research outputs found

    Dilemmas in Rescue and Reintegration: A critical assessment of India’s policies for children trafficked for labour exploitation

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    This paper provides a comprehensive analysis of the Indian government’s efforts to combat pervasive child trafficking for labour exploitation through rescue and reintegration of affected children. It evaluates the extensive policy and legal frameworks against on-the-ground realities in the states of Bihar and Rajasthan, using empirical findings from a qualitative study carried out by the FXB Center for Health & Human Rights at Harvard University. The results demonstrate that current practices fail to adhere to human rights norms or protect rescued children from risk of future exploitation. They underscore important challenges in the rescue and reintegration of trafficked children, and call into question the singular focus on this category of post-harm response over preventative interventions. The findings point to a critical need for future research, sustained multi-stakeholder discussion and concrete reforms

    Review of Benefits of Nature Experience for Young Children

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    Progressing urbanization is having an impact on people’s lifestyles. Increasing indoor time results in the deprivation of human’s proximity to nature. Richard Louv (2008) coined the term “nature deficit disorder”, conceptualized the increasing phenomenon of children suffering from anxiety, ADHD, and obesity due to spending less time in nature and more time indoor. There is a growing body of literature focusing on the benefits of nature experience, nature exposure on young children’s physiological and psychological well-beings, such as physical health, attention, executive function, and behavioral regulation etc. This review focuses on the research articles that investigated the influence of nature contact on preschool-aged children. This review’s overarching question is: what benefits does nature exposure have on preschool-age children

    Decoupling of nutrient stoichiometry in Suaeda glauca (Bunge) senesced leaves under salt treatment

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    The stoichiometry of senesced leaves is pivotal in nutrient cycling and can be significantly influenced by soil salinization, a rising global issue threatening the functionality of ecosystems. However, the impacts of soil salinization on senesced leaf stoichiometry are not fully understood. In this study, we conducted a pot experiment with varying soil salt concentrations to examine their influence on the concentrations and stoichiometric ratios of nitrogen (N), phosphorus (P), sodium (Na), potassium (K), calcium (Ca), magnesium (Mg), and zinc (Zn) in the senesced leaves of Suaeda glauca (Bunge). Compared to the control group, salt treatments significantly enhanced Na concentration while diminishing the concentrations of K, Ca, Mg, Zn, N, and P. Interestingly, as salinity levels escalated, N concentration maintained stability, whereas P concentration exhibited an increasing trend. Moreover, K, Ca, and Mg significantly declined as salt levels rose. Salt treatments brought about significant changes in stoichiometric ratios, with the N:P, K:Na, N:Na, N:Mg, and Ca : Mg ratios dropping and the N:Ca and N:K ratios rising, illustrating the varying nutrient coupling cycles under different salt conditions. These findings shed light on the plasticity of stoichiometric traits in S. glauca senesced leaves in response to soil salinization shifts, which could potentially offer insights into nutrient cycling reactions to soil salinization

    War, Revolution and Design: exploring pedagogy, practice based research and costume for performance through the Russian avant-garde theatre

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    This article recounts an edited conversation that took place at the V & A symposium ‘Russian Avant-garde Theatre: War Revolution and Design’ held on the 24 January 2014, which accompanied the exhibition of the same name. Fashion historian Amber Jane Butchart (V&A and London College of Fashion, University of the Arts London) led Melissa Trimingham (University of Kent) and Donatella Barbieri (London College of Fashion, University of the Arts London) in a conversation discussing the relationship of Russian costume design with the avant-garde in early Modernism across Europe

    QT Prolongation and Life Threatening Ventricular Tachycardia in a Patient Injected With Intravenous Meperidine (DemerolÂź)

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    QT prolongation is a serious adverse drug effect, which is associated with an increased risk of Torsade de pointes and sudden death. Many drugs, including both cardiac and non-cardiac drugs, have been reported to cause prolongation of QT interval. Although meperidine has not been considered proarrhythmic, we present a unique case of a 16-year-old boy without an underlying cardiac disease, who developed polymorphic ventricular tachycardia, ventricular fibrillation and QT prolongation after an intravenous meperidine injection. He had no mutation in long QT syndrome genes (KCNQ1, KCNH2, and SCN5A), but single nucleotide polymorphisms were reported, including H558R in SCNA5A and K897T in KCNH2

    Exaggerated QT prolongation after cardioversion of atrial fibrillation

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    AbstractOBJECTIVESThe purpose of this study was to test the hypothesis that the extent of drug-induced QT prolongation by dofetilide is greater in sinus rhythm (SR) after cardioversion compared with during atrial fibrillation (AF).BACKGROUNDAnecdotes suggest that when action potential–prolonging antiarrhythmic drugs are used for AF, excessive QT prolongation and torsades de pointes (TdP) often occur shortly after sinus rhythm is restored.METHODSQT was measured in nine patients with AF who received two identical infusions of dofetilide: 1) before elective direct current cardioversion and 2) within 24 h of restoration of SR.RESULTSDuring AF, dofetilide did not prolong QT (baseline: 368 ± 48 ms vs. drug: 391 ± 60, p = NS) whereas during SR, QT was prolonged from 405 ± 55 to 470 ± 67 ms (p < 0.01). In four patients (group I), the SR dofetilide infusion was terminated early because QT prolonged to >500 ms, and one patient developed asymptomatic nonsustained TdP. The remaining five patients (group II) received the entire dose during SR. Although ΔQT was greater in group I during SR (91 ± 22 vs. 45 ± 25 ms, p < 0.05), plasma dofetilide concentrations during SR were similar in the two groups (2.72 ± 0.96 vs. 2.77 ± 0.25 ng/ml), and in AF (2.76 ± 1.22 ng/ml). ΔQT in SR correlated inversely with baseline SR heart rate (r = −0.69, p < 0.05), and QT dispersion developing during the infusion (r = 0.79, p < 0.01).CONCLUSIONSShortly after restoration of SR, there was increased sensitivity to QT prolongation by this IKr-specific blocker. Slower heart rates after cardioversion and QT dispersion during treatment appear to be important predictors of this response
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