Networking, Resource Acquisition, and the Performance of Small and Medium-Sized Enterprises: An Empirical Study of Three Major Cities in China

Previously, resource-based view (RBV) research has focused on the characteristics of resources, paying less attention to the relationship between resource acquisition and the acquisition method. In addition, entrepreneurship research has focused a lot on the firm’s entrepreneurial network to explain performance. This network is critical not only to resource acquisition but also to overall firm performance. The results of a study of small and medium-sized firms in three major Chinese cities support these notions. The results differ when dividing the sample into two groups (young vs. old).resource acquisition, networking, performance, SMEs, entrepreneurship

Artificial disc and vertebra system: a novel motion preservation device for cervical spinal disease after vertebral corpectomy

OBJECTIVE: To determine the range of motion and stability of the human cadaveric cervical spine after the implantation of a novel artificial disc and vertebra system by comparing an intact group and a fusion group. METHODS: Biomechanical tests were conducted on 18 human cadaveric cervical specimens. The range of motion and the stability index range of motion were measured to study the function and stability of the artificial disc and vertebra system of the intact group compared with the fusion group. RESULTS: In all cases, the artificial disc and vertebra system maintained intervertebral motion and reestablished vertebral height at the operative level. After its implantation, there was no significant difference in the range of motion (ROM) of C3-7 in all directions in the non-fusion group compared with the intact group (p>;0.05), but significant differences were detected in flexion, extension and axial rotation compared with the fusion group (

A Survey on In-context Learning

With the increasing ability of large language models (LLMs), in-context learning (ICL) has become a new paradigm for natural language processing (NLP), where LLMs make predictions only based on contexts augmented with a few examples. It has been a new trend to explore ICL to evaluate and extrapolate the ability of LLMs. In this paper, we aim to survey and summarize the progress and challenges of ICL. We first present a formal definition of ICL and clarify its correlation to related studies. Then, we organize and discuss advanced techniques, including training strategies, demonstration designing strategies, as well as related analysis. Finally, we discuss the challenges of ICL and provide potential directions for further research. We hope that our work can encourage more research on uncovering how ICL works and improving ICL.Comment: Papers collected until 2023/05/2

Fusion of Multi-Baseline and Multi-Orbit InSAR DEMs with Terrain Feature-Guided Filter

Interferometric synthetic aperture radar (InSAR) is an effective technology for generating high-precision digital elevation models (DEMs). However, the vertical accuracy of InSAR DEMs is limited by the contradiction between height measurement sensitivity and phase unwrapping reliability in terms of normal baseline length as well as data voids caused by layover or shadow effects. In order to alleviate these two unfavorable factors, in this study, a novel InSAR DEM fusion method with guided filter is developed and assessed with multiple bistatic TanDEM-X InSAR data pairs of different normal baselines acquired from different orbits. Unlike the widely used fusion method based on pixel-by-pixel weighted average, the guided-filter-based method incorporates local spatial context information into the fusion and can thus effectively alleviate the noise effect and automatically fill in data voids. As a result of the local edge-preserving capability of the guided filter, the proposed fusion method can preserve terrain details by maintaining gradient consistency and introducing terrain features as guidance image. Furthermore, the proposed fusion method is computationally efficient owing to the linear time complexity of guided filter. The experimental results show that the fused DEM with guided filter can depict terrain details well and smooth the “salt-and-pepper” noise and fill in almost all of the data voids. The root mean square error (RMSE) of the fused InSAR DEM with guided filter is lower than those of the weighted average fused InSAR DEM and the TanDEM-X DEM released by the German Aerospace Center (DLR), thus validating the effectiveness of the fusion method proposed in this study

Overexpression of TIMP3 Protects Against Cardiac Ischemia/Reperfusion Injury by Inhibiting Myocardial Apoptosis Through ROS/Mapks Pathway

Background/Aims: Myocardial ischemia/reperfusion (I/R) injury remains a great challenge in clinical therapy. Tissue inhibitor of metalloproteinases 3 (TIMP3) plays a crucial role in heart physiological and pathophysiological processes. However, the effects of TIMP3 on I/R injury remain unknown. Methods: C57BL/6 mice were infected with TIMP3 adenovirus by local delivery in myocardium followed by I/R operation or doxorubicin treatment. Neonatal rat cardiomyocytes were pretreated with TIMP3 adenovirus prior to anoxia/reoxygenation (A/R) treatment in vitro. Histology, echocardiography, in vivo phenotypical analysis, flow cytometry and western blotting were used to investigate the altered cardiac function and underlying mechanisms. Results: The results showed that upregulation of TIMP3 in myocardium markedly inhibited myocardial infarct areas and the cardiac dysfunction induced by I/R or by doxorubicin treatment. TUNEL staining revealed that TIMP3 overexpression attenuated I/R-induced myocardial apoptosis, accompanied by decreased Bax/Bcl-2 ratio, Cleaved Caspase-3 and Cleaved Caspase-9 expression. In vitro, A/R-induced cardiomyocyte apoptosis was abrogated by pharmacological inhibition of reactive oxygen species (ROS) production or MAPKs signaling. Attenuation of ROS production reversed A/R-induced MAPKs activation, whereas MAPKs inhibitors showed on effect on ROS production. Furthermore, in vivo or in vitro overexpression of TIMP3 significantly inhibited I/R- or A/R-induced ROS production and MAPKs activation. Conclusion: Our findings demonstrate that TIMP3 upregulation protects against cardiac I/R injury through inhibiting myocardial apoptosis. The mechanism may be related to inhibition of ROS-initiated MAPKs pathway. This study suggests that TIMP3 may be a potential therapeutic target for the treatment of I/R injury

Effects of Curing Conditions on the MECHANICAL and Microstructural Properties of Ultra-High-Performance Concrete (UHPC) Incorporating Iron Tailing Powder

It has been reported that iron tailing powder (ITP) has the potential to partially replace cement to prepare ultra-high-performance concrete (UHPC). However, the reactivity of ITP particles in concrete largely depends on the curing method. This study investigates the effects of curing conditions on the mechanical and microstructural properties of UHPC containing ITP. To achieve this objective, three research tasks are conducted, including (1) preparing seven concrete formulations by introducing ITP; (2) characterizing their mechanical performance under different curing regimes; and (3) analyzing their microstructure by XRD patterns, FTIR analysis, and SEM observation. The experimental results show that there is an optimum ITP dosage (15%) for their application. The concrete with 15% ITP under standard curing obtains 94.3 MPa at 7 days, their early-age strength could be even further increased by ~30% (warm-water curing) and ~35% (steamed curing). The steam curing regime stimulates the activity of ITP and refines the microstructure. This study demonstrates the potential of replacing Portland cement with ITP in UHPC production