Defect related switching field reduction in small magnetic particle arrays

An array of 42 mum square, 3 mum thick garnet particles has been studied. The strong crystalline uniaxial anisotropy of these particles results in the stable remanent state being single domain with magnetization parallel to the film normal. Magneto-optic measurements of individual particles provide distribution statistics for the easy-axis switching field H-sw, and the in-plane hard-axis effective anisotropy field, H-eff, which induces the formation of a metastable stripe domain structure. Both H-sw and H-eff are much smaller than the crystalline anisotropy field. Micromagnetic simulations show that the small H-sw cannot be attributed to shape anisotropy, but is consistent with smooth, localized reductions in the crystalline anisotropy caused by defects in either the particles or the substrate

A General Precipitation-Limited L_X-T-R Relation Among Early-Type Galaxies

The relation between X-ray luminosity (L_X) and ambient gas temperature (T) among massive galactic systems is an important cornerstone of both observational cosmology and galaxy-evolution modeling. In the most massive galaxy clusters, the relation is determined primarily by cosmological structure formation. In less massive systems, it primarily reflects the feedback response to radiative cooling of circumgalactic gas. Here we present a simple but powerful model for the L_X-T relation as a function of physical aperture R within which those measurements are made. The model is based on the precipitation framework for AGN feedback and assumes that the circumgalactic medium is precipitation-regulated at small radii and limited by cosmological structure formation at large radii. We compare this model with many different data sets and show that it successfully reproduces the slope and upper envelope of the L_X-T-R relation over the temperature range from ~0.2 keV through >10 keV. Our findings strongly suggest that the feedback mechanisms responsible for regulating star formation in individual massive galaxies have much in common with the precipitation-triggered feedback that appears to regulate galaxy-cluster cores.Comment: Submitted to ApJ, 9 pages, 3 figures (v2 fixes a few small typos

Detection, Analysis and Clinical Validation of Chromosomal Aberrations by Multiplex Ligation-Dependent Probe Amplification in Chronic Leukemia

Current diagnostic screening strategies based on karyotyping or fluorescent in situ hybridization (FISH) for detection of chromosomal abnormalities in chronic lymphocytic leukemia (CLL) are laborious, time-consuming, costly, and have limitations in resolution. Multiplex ligation-dependent probe amplification (MLPA) can simultaneously detect copy number changes of multiple loci in one simple PCR reaction, making it an attractive alternative to FISH. To enhance the clinical robustness and further harness MLPA technology for routine laboratory operations, we have developed and validated a protocol for comprehensive, automatic data analysis and interpretation. A training set of 50 normal samples was used to establish reference ranges for each individual probe, for the calling of statistically significant copy number changes. The maximum normal ranges of 2 and 3 standard deviations (SD) are distributed between 0.82 and 1.18 (Mean ± 2SD, 95% CI, P = 0.05), and between 0.73 and 1.27 (Mean ± 3SD, 99% CI, P = 0.01), respectively. We found an excellent correlation between MLPA and FISH with 93.6% concordance (P<0.0001) from a testing cohort of 100 clinically suspected CLL cases. MLPA analyses done on 94/100 patients showed sensitivity and specificity of 94.2% and 92.9%, respectively. MLPA detected additional copy number gains on 18q21.1 and chromosome 19, and novel micro-deletions at 19q13.43 and 19p13.2 loci in six samples. Three FISH-failed samples were tested positive by MLPA, while three 13q- cases with a low percentage of leukemia cells (7%, 12% and 19%) were not detected by MLPA. The improved CLL MLPA represents a high-throughput, accurate, cost-effective and user-friendly platform that can be used as a first-line screening test in a clinical laboratory

Bandpass Dependence of X-ray Temperatures in Galaxy Clusters

We explore the band dependence of the inferred X-ray temperature of the intracluster medium (ICM) for 192 well-observed galaxy clusters selected from the Chandra Data Archive. If the hot ICM is nearly isothermal in the projected region of interest, the X-ray temperature inferred from a broad-band (0.7-7.0 keV) spectrum should be identical to the X-ray temperature inferred from a hard-band (2.0-7.0 keV) spectrum. However, if unresolved cool lumps of gas are contributing soft X-ray emission, the temperature of a best-fit single-component thermal model will be cooler for the broad-band spectrum than for the hard-band spectrum. Using this difference as a diagnostic, the ratio of best-fitting hard-band and broad-band temperatures may indicate the presence of cooler gas even when the X-ray spectrum itself may not have sufficient signal-to-noise to resolve multiple temperature components. To test this possible diagnostic, we extract X-ray spectra from core-excised annular regions for each cluster in our archival sample. We compare the X-ray temperatures inferred from single-temperature fits when the energy range of the fit is 0.7-7.0 keV (broad) and when the energy range is 2.0/(1+z)-7.0 keV (hard). We find that the hard-band temperature is significantly higher, on average, than the broad-band temperature. Upon further exploration, we find this temperature ratio is enhanced preferentially for clusters which are known merging systems. In addition, cool-core clusters tend to have best-fit hard-band temperatures that are in closer agreement with their best-fit broad-band temperatures. We show, using simulated spectra, that this diagnostic is sensitive to secondary cool components (TX = 0.5-3.0 keV) with emission measures >10-30% of the primary hot component.Comment: Accepted for publication in Ap

No planet for HD 166435

The G0V star HD166435 has been observed by the fiber-fed spectrograph ELODIE as one of the targets in the large extra-solar planet survey that we are conducting at the Observatory of Haute-Provence. We detected coherent, low-amplitude, radial-velocity variations with a period of 3.7987days, suggesting a possible close-in planetary companion. Subsequently, we initiated a series of high-precision photometric observations to search for possible planetary transits and an additional series of CaII H and K observations to measure the level of surface magnetic activity and to look for possible rotational modulation. Surprisingly, we found the star to be photometrically variable and magnetically active. A detailed study of the phase stability of the radial-velocity signal revealed that the radial-velocity variability remains coherent only for durations of about 30days. Analysis of the time variation of the spectroscopic line profiles using line bisectors revealed a correlation between radial velocity and line-bisector orientation. All of these observations, along with a one-quarter cycle phase shift between the photometric and the radial-velocity variationss, are well explained by the presence of dark photospheric spots on HD166435. We conclude that the radial-velocity variations are not due to gravitational interaction with an orbiting planet but, instead, originate from line-profile changes stemming from star spots on the surface of the star. The quasi-coherence of the radial-velocity signal over more than two years, which allowed a fair fit with a binary model, makes the stability of this star unusual among other active stars. It suggests a stable magnetic field orientation where spots are always generated at about the same location on the surface of the star.Comment: 9 pages, 8 figures, Accepted for publication in A&

A Deep Look at the Emission-Line Nebula in Abell 2597

The close correlation between cooling flows and emission-line nebulae in clusters of galaxies has been recognized for over a decade and a half, but the physical reason for this connection remains unclear. Here we present deep optical spectra of the nebula in Abell 2597, one of the nearest strong cooling-flow clusters. These spectra reveal the density, temperature, and metal abundances of the line-emitting gas. The abundances are roughly half-solar, and dust produces an extinction of at least a magnitude in V. The absence of [O III] 4363 emission rules out shocks as a major ionizing mechanism, and the weakness of He II 4686 rules out a hard ionizing source, such as an active galactic nucleus or cooling intracluster gas. Hot stars are therefore the best candidate for producing the ionization. However, even the hottest O stars cannot power a nebula as hot as the one we see. Some other nonionizing source of heat appears to contribute a comparable amount of power. We show that the energy flux from a confining medium can become important when the ionization level of a nebula drops to the low levels seen in cooling-flow nebulae. We suggest that this kind of phenomenon, in which energy fluxes from the surrounding medium augment photoelectric heating, might be the common feature underlying the diverse group of objects classified as LINERS.Comment: 33 Latex pages, including 16 Postscript figures, to appear in 1997 September 1 Astrophysical Journa

The X-ray Properties of Optically Selected Clusters of Galaxies

We present the results of Chandra and Suzaku X-ray observations of nine moderate-redshift (0.16 < z < 0.42) clusters discovered via the Red-sequence Cluster Survey (RCS). Surface brightness profiles are fitted to beta models, gas masses are determined, integrated spectra are extracted within R2500, and X-ray temperatures and luminosities are inferred. The Lx-Tx relationship expected from self-similar evolution is tested by comparing this sample to our previous X-ray investigation of nine high-redshift (0.6 < z < 1.0) optically selected clusters. We find that optically selected clusters are systematically less luminous than X-ray selected clusters of similar X-ray temperature at both moderate and high-z. We are unable to constrain evolution in the Lx-Tx relation with these data, but find it consistent with no evolution, within relatively large uncertainties. To investigate selection effects, we compare the X-ray properties of our sample to those of clusters in the representative X-ray selected REXCESS sample, also determined within R2500. We find that while RCS cluster X-ray properties span the entire range of those of massive clusters selected by other methods, their average X-ray properties are most similar to those of dynamically disturbed X-ray selected clusters. This similarity suggests that the true cluster distribution might contain a higher fraction of disturbed objects than are typically detected in X-ray selected surveys.Comment: 13 pages, 5 figures; accepted for publication in MNRAS. Figure quality reduced to comply with arXiv file size requirement