177 research outputs found

    Violencia familiar y autoestima en estudiantes de secundaria de una institución educativa de Nuevo Chimbote, 2023

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    El presente estudio se desarrolló con el fin de determinar la relación entre la violencia familiar y la autoestima en estudiantes adolescentes de una Institución educativa de Nuevo Chimbote, 2023. Para ello se empleó un enfoque cuantitativo con alcance correlacional y diseño no experimental. En cuanto a la muestra, se evaluó a 606 adolescentes, los cuales oscilaban entre los 12 y 18 años de edad. Durante esta investigación, se utilizaron dos instrumentos: el Cuestionario de Violencia Familiar (VIFA) y la Escala de Autoestima de Rosenberg (EAR) versión adaptada al español por Atienza y sus colaboradores. En cuanto a los resultados de la investigación, se encontró una correlación inversa negativa media (r= - 0,426**) entre ambas variables, en cuanto al sexo en ambas poblaciones se halló una correlación inversa y significativa donde en mujeres en mujeres se muestra un efecto negativo medio entre las variables VF y A (r= -,426**); no obstante, en varones es ligeramente más bajo (r=-,394**); además según violencia en la figura parental encontramos una correlación inversa y significativa en el que en hijos de padres que sufrieron violencia existe un efecto negativo medio (r= -,411**), paralelamente pero levemente más bajo en hijos de padres que no sufrieron violencia (r= -,395**). Finalmente, se llegó a la conclusión de la existencia de una correlación inversa negativa media entre violencia familiar y la autoestima en estudiantes adolescentes de una Institución educativa de Nuevo Chimbote, 2023

    Robust estimation of bacterial cell count from optical density

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    Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data

    Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

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    Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

    International Nosocomial Infection Control Consortiu (INICC) report, data summary of 43 countries for 2007-2012. Device-associated module

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    We report the results of an International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2007-December 2012 in 503 intensive care units (ICUs) in Latin America, Asia, Africa, and Europe. During the 6-year study using the Centers for Disease Control and Prevention's (CDC) U.S. National Healthcare Safety Network (NHSN) definitions for device-associated health care–associated infection (DA-HAI), we collected prospective data from 605,310 patients hospitalized in the INICC's ICUs for an aggregate of 3,338,396 days. Although device utilization in the INICC's ICUs was similar to that reported from ICUs in the U.S. in the CDC's NHSN, rates of device-associated nosocomial infection were higher in the ICUs of the INICC hospitals: the pooled rate of central line–associated bloodstream infection in the INICC's ICUs, 4.9 per 1,000 central line days, is nearly 5-fold higher than the 0.9 per 1,000 central line days reported from comparable U.S. ICUs. The overall rate of ventilator-associated pneumonia was also higher (16.8 vs 1.1 per 1,000 ventilator days) as was the rate of catheter-associated urinary tract infection (5.5 vs 1.3 per 1,000 catheter days). Frequencies of resistance of Pseudomonas isolates to amikacin (42.8% vs 10%) and imipenem (42.4% vs 26.1%) and Klebsiella pneumoniae isolates to ceftazidime (71.2% vs 28.8%) and imipenem (19.6% vs 12.8%) were also higher in the INICC's ICUs compared with the ICUs of the CDC's NHSN

    Observation of medium-induced yield enhancement and acoplanarity broadening of low-pTp_\mathrm{T} jets from measurements in pp and central Pb-Pb collisions at sNN=5.02\sqrt{s_{\rm NN}}=5.02 TeV

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    International audienceThe ALICE Collaboration reports the measurement of semi-inclusive distributions of charged-particle jets recoiling from a high transverse momentum (high pTp_{\rm T}) hadron trigger in proton-proton and central Pb-Pb collisions at sNN=5.02\sqrt{s_{\rm NN}} = 5.02 TeV. A data-driven statistical method is used to mitigate the large uncorrelated background in central Pb-Pb collisions. Recoil jet distributions are reported for jet resolution parameter R=0.2R=0.2, 0.4, and 0.5 in the range 7<pT,jet<1407 < p_{\rm T,jet} < 140 GeV/c/c and trigger-recoil jet azimuthal separation π/2<Δφ<π\pi/2 < \Delta\varphi < \pi. The measurements exhibit a marked medium-induced jet yield enhancement at low pTp_{\rm T} and at large azimuthal deviation from Δφπ\Delta\varphi\sim\pi. The enhancement is characterized by its dependence on Δφ\Delta\varphi, which has a slope that differs from zero by 4.7σ\sigma. Comparisons to model calculations incorporating different formulations of jet quenching are reported. These comparisons indicate that the observed yield enhancement arises from the response of the QGP medium to jet propagation

    Probing the Chiral Magnetic Wave with charge-dependent flow measurements in Pb-Pb collisions at the LHC

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    International audienceThe Chiral Magnetic Wave (CMW) phenomenon is essential to provide insights into the strong interaction in QCD, the properties of the quark-gluon plasma, and the topological characteristics of the early universe, offering a deeper understanding of fundamental physics in high-energy collisions. Measurements of the charge-dependent anisotropic flow coefficients are studied in Pb-Pb collisions at center-of-mass energy per nucleon-nucleon collision sNN=\sqrt{s_{\mathrm{NN}}}= 5.02 TeV to probe the CMW. In particular, the slope of the normalized difference in elliptic (v2v_{2}) and triangular (v3v_{3}) flow coefficients of positively and negatively charged particles as a function of their event-wise normalized number difference, is reported for inclusive and identified particles. The slope r3Normr_{3}^{\rm Norm} is found to be larger than zero and to have a magnitude similar to r2Normr_{2}^{\rm Norm}, thus pointing to a large background contribution for these measurements. Furthermore, r2Normr_{2}^{\rm Norm} can be described by a blast wave model calculation that incorporates local charge conservation. In addition, using the event shape engineering technique yields a fraction of CMW (fCMWf_{\rm CMW}) contribution to this measurement which is compatible with zero. This measurement provides the very first upper limit for fCMWf_{\rm CMW}, and in the 10-60% centrality interval it is found to be 26% (38%) at 95% (99.7%) confidence level

    Charged-particle production as a function of the relative transverse activity classifier in pp, p-Pb, and Pb-Pb collisions at the LHC

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    International audienceMeasurements of charged-particle production in pp, p-Pb, and Pb-Pb collisions in the toward, away, and transverse regions with the ALICE detector are discussed. These regions are defined event-by-event relative to the azimuthal direction of the charged trigger particle, which is the reconstructed particle with the largest transverse momentum (pTtrigp_{\mathrm{T}}^{\rm trig}) in the range 8<pTtrig<158<p_{\mathrm{T}}^{\rm trig}<15 GeV/c/c. The toward and away regions contain the primary and recoil jets, respectively; both regions are accompanied by the underlying event (UE). In contrast, the transverse region perpendicular to the direction of the trigger particle is dominated by the so-called UE dynamics, and includes also contributions from initial- and final-state radiation. The relative transverse activity classifier, RT=NchT/NchTR_{\mathrm{T}}=N_{\mathrm{ch}}^{\mathrm{T}}/\langle N_{\mathrm{ch}}^{\mathrm{T}}\rangle, is used to group events according to their UE activity, where NchTN_{\mathrm{ch}}^{\mathrm{T}} is the charged-particle multiplicity per event in the transverse region and NchT\langle N_{\mathrm{ch}}^{\mathrm{T}}\rangle is the mean value over the whole analysed sample. The energy dependence of the RTR_{\mathrm{T}} distributions in pp collisions at s=2.76\sqrt{s}=2.76, 5.02, 7, and 13 TeV is reported, exploring the Koba-Nielsen-Olesen (KNO) scaling properties of the multiplicity distributions. The first measurements of charged-particle pTp_{\rm T} spectra as a function of RTR_{\mathrm{T}} in the three azimuthal regions in pp, p-Pb, and Pb-Pb collisions at sNN=5.02\sqrt{s_{\rm NN}}=5.02 TeV are also reported. Data are compared with predictions obtained from the event generators PYTHIA 8 and EPOS LHC. This set of measurements is expected to contribute to the understanding of the origin of collective-like effects in small collision systems (pp and p-Pb)

    Measurement of (anti)alpha production in central Pb-Pb collisions at sNN\sqrt{s_{\rm NN}} = 5.02 TeV

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    International audienceIn this letter, measurements of (anti)alpha production in central (0-10%) Pb-Pb collisions at a center-of-mass energy per nucleon-nucleon pair of sNN\sqrt{s_{\rm NN}} = 5.02 TeV are presented, including the first measurement of an antialpha transverse-momentum spectrum. Owing to its large mass, (anti)alpha production yields and transverse-momentum spectra are of particular interest because they provide a stringent test of particle production models. The averaged antialpha and alpha spectrum is included into a common blast-wave fit with lighter particles, indicating that the (anti)alpha also participates in the collective expansion of the medium created in the collision. A blast-wave fit including only protons, (anti)alpha, and other light nuclei results in a similar flow velocity as the fit that includes all particles. A similar flow velocity, but a significantly larger kinetic freeze-out temperature is obtained when only protons and light nuclei are included in the fit. The coalescence parameter B4B_4 is well described by calculations from a statistical hadronization model but significantly underestimated by calculations assuming nucleus formation via coalescence of nucleons. Similarly, the (anti)alpha-to-proton ratio is well described by the statistical hadronization model. On the other hand, coalescence calculations including approaches with different implementations of the (anti)alpha substructure tend to underestimate the data

    Light-flavor particle production in high-multiplicity pp collisions at s\sqrt{s} = 13 TeV as a function of transverse spherocity

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    Results on the transverse spherocity dependence of light-flavor particle production (π\pi, K, p, ϕ\phi, K0{\rm K^{*0}}, KS0{\rm K}^{0}_{\rm{S}}, Λ\Lambda, Ξ\Xi) at midrapidity in high-multiplicity pp collisions at s\sqrt{s} = 13 TeV were obtained with the ALICE apparatus. The transverse spherocity estimator (SOpT=1S_{\text{O}}^{p_{\rm T}=1}) categorizes events by their azimuthal topology. Utilizing narrow selections on SOpT=1S_{\text{O}}^{p_{\rm T}=1}, it is possible to contrast particle production in collisions dominated by many soft initial interactions with that observed in collisions dominated by one or more hard scatterings. Results are reported for two multiplicity estimators covering different pseudorapidity regions. The SOpT=1S_{\text{O}}^{p_{\rm T}=1} estimator is found to effectively constrain the hardness of the events when the midrapidity (η<0.8\left | \eta \right |< 0.8) estimator is used. The production rates of strange particles are found to be slightly higher for soft isotropic topologies, and severely suppressed in hard jet-like topologies. These effects are more pronounced for hadrons with larger mass and strangeness content, and observed when the topological selection is done within a narrow multiplicity interval. This demonstrates that an important aspect of the universal scaling of strangeness enhancement with final-state multiplicity is that high-multiplicity collisions are dominated by soft, isotropic processes. On the contrary, strangeness production in events with jet-like processes is significantly reduced. The results presented in this article are compared with several QCD-inspired Monte Carlo event generators. Models that incorporate a two-component phenomenology, either through mechanisms accounting for string density, or thermal production, are able to describe the observed strangeness enhancement as a function of SOpT=1S_{\text{O}}^{p_{\rm T}=1}.Results on the transverse spherocity dependence of light-flavor particle production (π\pi, K, p, ϕ\phi, K0{\rm K^{*0}}, KS0{\rm K}^{0}_{\rm{S}}, Λ\Lambda, Ξ\Xi) at midrapidity in high-multiplicity pp collisions at s=13\sqrt{s} = 13 TeV were obtained with the ALICE apparatus. The transverse spherocity estimator (SOpT=1S_{{\rm O}}^{{\it p}_{\rm T}=1}) categorizes events by their azimuthal topology. Utilizing narrow selections on SOpT=1S_{\text{O}}^{{\it p}_{\rm T}=1}, it is possible to contrast particle production in collisions dominated by many soft initial interactions with that observed in collisions dominated by one or more hard scatterings. Results are reported for two multiplicity estimators covering different pseudorapidity regions. The SOpT=1S_{{\rm O}}^{{\it p}_{\rm T}=1} estimator is found to effectively constrain the hardness of the events when the midrapidity (η<0.8\left | \eta \right |< 0.8) estimator is used. The production rates of strange particles are found to be slightly higher for soft isotropic topologies, and severely suppressed in hard jet-like topologies. These effects are more pronounced for hadrons with larger mass and strangeness content, and observed when the topological selection is done within a narrow multiplicity interval. This demonstrates that an important aspect of the universal scaling of strangeness enhancement with final-state multiplicity is that high-multiplicity collisions are dominated by soft, isotropic processes. On the contrary, strangeness production in events with jet-like processes is significantly reduced. The results presented in this article are compared with several QCD-inspired Monte Carlo event generators. Models that incorporate a two-component phenomenology, either through mechanisms accounting for string density, or thermal production, are able to describe the observed strangeness enhancement as a function of SOpT=1S_{{\rm O}}^{{\it p}_{\rm T}=1}
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