91 research outputs found

    DOWN AND DIRTY LOMBROSO’S BORN TO CRIME, THE MORPHOANTHROPOLOGY AND THE IGNORED HUMAN NEUROPHYSIOLOGY: A CRITICAL REVIEW ON A HISTORICAL CONTEXT

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    Lombroso\u27s theories, in 1800s, gave a strong shock in the international scientific community , regarding the correlation between the human morphology and its tendency to crime. They were followed, especially out of the Europe, and still are being discussed. But, in that century, they were enriched researches on human neurophysiology, which then would be further down to our time and that they denied sharply the Lombroso concepts. In short, the ignored neurophysiology, to the detriment of hypothesis which theorized the tendency to crime as an expression of the physical features of the individual, the whole body, from the face, limbs, ears, the shape of the skull. In this review, are made some critical remarks about Lombroso concepts, on \u27atavism, the people considered inferior on the basis of their physical appearance, in other words what was called morphoanthropology. At the same time, this work emphasizes instead the \u27importance of neurophysiological aspects of\u27 individual tending to crime, that are the basis of abnormal acts against the society \u27and that are related to the dysfunction of certain brain areas, such as the frontal cortex and limbic cortex, under the influence of genotype and environmental factors

    Median occipital fossa: is it really a sign of crime or simply an anatomical variant?

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    Anatomical variants are alterations of the form, thickness, length, width, position of organs and anatomic structures that can cause problems of a functional nature. They can be vascular, bony, muscular and more. They represent anomalies that may cause disturbances or do not cause changes in functions. The criminologist Cesare Lombroso had correlated the anatomical variations to the criminal tendency. The most emblematic case was that related to the alleged brigand Villella, on which Lombroso, performing the autopsy, found in the skull the so-called medial occipital fossa or a third dimple. He stated that the median occipital dimple was considered a sign of atavism, the expression of the criminal. In fact all the anatomical variants described by Lombroso are variations of normality. No one ever said that anatomical variants were a sign of crime. In conclusion, anatomical variants cannot be related to crime tendency, therefore the debated median occipital fossa is only and simply an anatomical variant

    Evaluation of the capillary electrophoresis method for measurement of immunoglobulin concentration in ewe colostrum

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    ABSTRACT Capillary electrophoresis (CE) is a technique routinely used in clinical laboratories that allows the separation and quantification of blood serum proteins in a rapid, precise, accurate, and inexpensive manner. Recently, CE has been proposed to separate and measure colostral proteins, but an evaluation of the agreement between CE and radial immunodiffusion (RID) method, currently used to quantify IgG in colostrum, is still lacking. The purpose of this study was to test the ability of a CE instrument, normally used in blood serum protein analysis, to realize the correct quantification of total Ig concentration in ewe colostrum, using RID assay as reference. Colostrum samples (n = 68) were collected from 35 multiparous Sarda ewes at first milking (n = 33) and at 24 h postpartum (n = 35). The mean ± standard deviation of IgG concentration measured by RID and whey colostrum total Ig concentration measured by CE were 54.76 ± 41.82 g/L and 54.70 ± 41.43 g/L, respectively. Lin's concordance correlation coefficient (r = 0.993; 95% confidence interval=0.989 to 0.996) and linear regression analysis results (RID = 1.0022CE − 0.063; R 2 = 0.986) showed an excellent agreement between these 2 methods. Bland-Altman analysis confirmed that CE method can be a suitable alternative to RID: the mean of the differences between CE and RID was −0.055 ± 4.95 g/L (95% confidence interval=−1.25 to 1.14 g/L) and the agreement limits were −9.75 to 9.60 g/L (low limit 95% confidence interval=−11.82 to −7.68 g/L; high limit 95% confidence interval=7.57 to 11.72 g/L). In conclusion, the current study indicates that CE method may be a reliable tool for the quantification of the total Ig concentration in ewe colostrum

    Prevalence, phenotypic and genetic diversity of Campylobacter in poultry fresh meat and poultry products on retail sale in Tuscany (Italy)

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    In this study, the prevalence of Campylobacter spp. in poultry fresh meat and ready‑to‑cook products was evaluated. Seventy‑three samples were collected at retail level from supermarkets and discount stores, obtaining 61.6% positivity. Of 133 Campylobacter isolates, 86 strains (Campylobacter coli, 58.1% and Campylobacter jejuni, 41.9%) were selected for characterisation on the basis of their SmaI and kpnI pulsed field gel‑electrophoresis (PFGE) profiles, to exclude clonal replicates. Campylobacters resulted highly resistant to tetracycline, ciprofloxacin, and nalidixic acid (79.1%, 72.1% and 65.1%, respectively); 50% of C. coli and 13.9% of C. jejuni were resistant to ciprofloxacin and erythromycin, the most important antimicrobials for human campylobacteriosis therapy. Five C. coli were resistant to 5/7 of the tested antimicrobials. HS4c was the prevailing C. jejuni serotype group (22.3%), whereas 8 other serotypes were identified in low percentages. SmaI and kpnI profiles showed a wide variability. The survey showed a high Campylobacter contamination of poultry meat and poultry products at retail level in Tuscany, Italy. A wide strains’ heterogeneity and a remarkable level of strains’ antimicrobial resistance have been reported, confirming the need for an improvement of specific preventive measures along the production chain

    Synergism between bisphenol a exposure and overweight/obesity in increasing the malignancy risk in a cohort of patients with thyroid nodules

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    BPA exposure conferred higher risk of thyroid cancer only in case of concomitant overweight/obesity, therefore suggesting a synergistic action between BPA and the excess of adipose tissue in promoting thyroid carcinogenesis

    Diagnostic accuracy of a new antigen test for sars-cov-2 detection

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    Background and aims: Quick and reliable diagnostic tools play an important role in con-trolling the spread of the SARS-Cov-2 pandemic. The aim of this study was to evaluate the diagnostic accuracy of a new cyto-salivary antigen test aimed at detecting the presence of antigens for SARS-CoV-2, as compared by the gold standard RT-PCR and a lateral flow test. Methods: A total of 433 healthy volunteers were enrolled in the study and the sensitivity and specificity of the new cyto-salivary antigen test were calculated, as compared to the RT-PCR nasopharyngeal swab and to the lateral flow test. Results: A total of 433 samples were collected and tested at the Mediterranean Fair in Palermo from February 2021 until April 2021. The new cyto-salivary antigen had a sensitivity of 100% and a specificity of 94.2%. The sensitivity and the specificity of the lateral flow test were 55% and 100%, respectively. Conclusions: The new cyto-salivary antigen test detected more positive cases than the RT-PCR in a sample of asymptomatic subjects, demonstrating to be a promising tool for a more sensitive diagnosis of COVID-19. Further studies are warranted to better characterize its diagnostic accuracy

    Diagnostic Accuracy of a New Antigen Test for SARS-CoV-2 Detection

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    Background and aims: Quick and reliable diagnostic tools play an important role in controlling the spread of the SARS-Cov-2 pandemic. The aim of this study was to evaluate the diagnostic accuracy of a new cyto-salivary antigen test aimed at detecting the presence of antigens for SARS-CoV-2, as compared by the gold standard RT-PCR and a lateral flow test. Methods: A total of 433 healthy volunteers were enrolled in the study and the sensitivity and specificity of the new cyto-salivary antigen test were calculated, as compared to the RT-PCR nasopharyngeal swab and to the lateral flow test. Results: A total of 433 samples were collected and tested at the Mediterranean Fair in Palermo from February 2021 until April 2021. The new cyto-salivary antigen had a sensitivity of 100% and a specificity of 94.2%. The sensitivity and the specificity of the lateral flow test were 55% and 100%, respectively. Conclusions: The new cyto-salivary antigen test detected more positive cases than the RT-PCR in a sample of asymptomatic subjects, demonstrating to be a promising tool for a more sensitive diagnosis of COVID-19. Further studies are warranted to better characterize its diagnostic accuracy

    Surgical treatment of a giant tibial high-grade mixofibrosarcoma with preservation of limb function: a case report

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    Myxofibrosarcoma is one of the most common sarcomas in elderly patients showing a slight male prevalence. The tumor is mainly located in lower and upper extremities and rarely in trunk, neck and feet. We present a case of a 84-year-old man referred to our tumour center with a giant and neglected high-grade tibial myxofibrosarcoma in the anteromedial side of tibial mid-diaphysis. Large size lesions in association with older age may jeopardise the maintenance of limb vitality, vascularity and stability
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