294 research outputs found
Testing Helioseismic-Holography Inversions for Supergranular Flows Using Synthetic Data
Supergranulation is one of the most visible length scales of solar convection
and has been studied extensively by local helioseismology. We use synthetic
data computed with the Seismic Propagation through Active Regions and
Convection (SPARC) code to test regularized-least squares (RLS) inversions of
helioseismic holography measurements for a supergranulation-like flow. The code
simulates the acoustic wavefield by solving the linearized three-dimensional
Euler equations in Cartesian geometry. We model a single supergranulation cell
with a simple, axisymmetric, mass-conserving flow.
The use of simulated data provides an opportunity for direct evaluation of
the accuracy of measurement and inversion techniques. The RLS technique applied
to helioseismic-holography measurements is generally successful in reproducing
the structure of the horizontal flow field of the model supergranule cell. The
errors are significant in horizontal-flow inversions near the top and bottom of
the computational domain as well as in vertical-flow inversions throughout the
domain. We show that the errors in the vertical velocity are due largely to
cross talk from the horizontal velocity.Comment: 22 pages, 12 figues, accepted for publication in Solar Physic
Delivering Urban Wellbeing through Transformative Community Enterprise
(c) The Author/sChristchurch, New Zealan
More than monitoring: Developing impact measures for transformative social enterprise
Meeting the Sustainable Development Goals by 2030 involves transformational change in the
business of business, and social enterprises can lead the way in such change. We studied Cultivate,
one such social enterprise in Christchurch, New Zealand, a city still recovering from the 2010/11
Canterbury earthquakes. Cultivate works with vulnerable youth to transform donated compost into
garden vegetables for local restaurants and businesses. Cultivateās objectives align with SDG
concerns with poverty and hunger (1 & 2), social protection (3 & 4), and sustainable human
settlements (6 & 11). Like many grant-supported organisations, Cultivate is required to track and
measure its progress. Given the organisationās holistic objectives, however, adequately accounting
for its impact reporting is not straightforward. Our action research project engaged Cultivate staff and
youth-workers to generate meaningful ways of measuring impact. Elaborating the Community
Economy Return on Investment tool (CEROI), we explore how participatory audit processes can
capture impacts on individuals, organisations, and the wider community in ways that extend capacities
to act collectively. We conclude that Cultivate and social enterprises like it offer insights regarding
how to align values and practices, commercial activity and wellbeing in ways that accrue to
individuals, organisations and the broader civic-community
Journeying from āIā to āweā: assembling hybrid caring collectives of geography doctoral scholars
This is an Accepted Manuscript of an article published by Taylor & Francis in "Journal of Geography in Higher Education" on 15 June 2017, available at: https://www.tandfonline.com/doi/full/10.1080/03098265.2017.133529
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Evaluation of database technologies for the CTBT Knowledge Base prototype
This document examines a number of different software technologies in the rapidly changing field of database management systems, evaluates these systems in light of the expected needs of the Comprehensive Test Ban Treaty (CTBT) Knowledge Base, and makes some recommendations for the initial prototypes of the Knowledge Base. The Knowledge Base requirements are examined and then used as criteria for evaluation of the database management options. A mock-up of the data expected in the Knowledge Base is used as a basis for examining how four different database technologies deal with the problems of storing and retrieving the data. Based on these requirement and the results of the evaluation, the recommendation is that the Illustra database be considered for the initial prototype of the Knowledge Base. Illustra offers a unique blend of performance, flexibility, and features that will aid in the implementation of the prototype. At the same time, Illustra provides a high level of compatibility with the hardware and software environments present at the US NDC (National Data Center) and the PIDC (Prototype International Data Center)
Employment and Compliance with Pandemic Influenza Mitigation Recommendations
Noncompliance may result from job insecurity and financial problems associated with missing work
A depolarization and attenuation experiment using the COMSTAR and CTS satellites
Monthly and annual percent-of-time data on ground rain fall rate and attenuation on satellite downlinks at 11.7 GHz, 19.04 GHz, and 28.56 GHz is presented. Equal probability values of attenuation and rain rate are compared for monthly, quarterly, half-year periods and for the entire year. Regression equations relating cross polarization isolation to the logarithm of attenuation are also presented
Creating the cultures of the future: cultural strategy, policy and institutions in Gramsci. Part three: Is there a theory of cultural policy in Gramsciās prison notebooks?
In this article, I argue that Gramsciās prison notes on questions of cultural strategy, policy and institutions, which have so far been largely overlooked by scholars, provide further analytical insights to those offered by his more general concepts. Together they enrich the theoretical underpinnings for critical frameworks of analysis as well as for radical practices of cultural strategy, cultural policy-making and cultural organisation. On the basis of a detailed analysis of these notes, I then answer the question of whether they amount to a theory of cultural policy
Endonuclease-independent LINE-1 retrotransposition at mammalian telomeres
Long interspersed element-1 (LINE-1 or L1) elements are abundant, non-long-terminal-repeat (non-LTR) retrotransposons that comprise 17% of human DNA(1). The average human genome contains similar to 80-100 retrotransposition- competent L1s (ref. 2), and they mobilize by a process that uses both the L1 endonuclease and reverse transcriptase, termed target-site primed reverse transcription(3-5). We have previously reported an efficient, endonuclease-independent L1 retrotransposition pathway (ENi) in certain Chinese hamster ovary (CHO) cell lines that are defective in the non-homologous end-joining (NHEJ) pathway of DNA double-strand-break repair(6). Here we have characterized ENi retrotransposition events generated in V3 CHO cells, which are deficient in DNA-dependent protein kinase catalytic subunit (DNA-PKcs) activity and have both dysfunctional telomeres and an NHEJ defect. Notably, similar to 30% of ENi retrotransposition events insert in an orientation-specific manner adjacent to a perfect telomere repeat (5'-TTAGGG-3'). Similar insertions were not detected among ENi retrotransposition events generated in controls or in XR-1 CHO cells deficient for XRCC4, an NHEJ factor that is required for DNA ligation but has no known function in telomere maintenance. Furthermore, transient expression of a dominant-negative allele of human TRF2 ( also called TERF2) in XRCC4-deficient XR-1 cells, which disrupts telomere capping, enables telomere-associated ENi retrotransposition events. These data indicate that L1s containing a disabled endonuclease can use dysfunctional telomeres as an integration substrate. The findings highlight similarities between the mechanism of ENi retrotransposition and the action of telomerase, because both processes can use a 3' OH for priming reverse transcription at either internal DNA lesions or chromosome ends(7,8). Thus, we propose that ENi retrotransposition is an ancestral mechanism of RNA-mediated DNA repair associated with non-LTR retrotransposons that may have been used before the acquisition of an endonuclease domain.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/62964/1/nature05560.pd
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