336 research outputs found
Experimental evaluation of 3D printed spiral phase plates for enabling an orbital angular momentum multiplexed radio system
This paper evaluates the performance of three-dimensionally (3D) printed spiral phase plates (SPPs) for enabling an orbital angular momentum (OAM) multiplexed radio system. The design and realization of the SPPs by means of additive manufacturing exploiting a high-permittivity material is described. Modes 1 and 2 SPPs are then evaluated at 15 GHz in terms of 3D complex radiation pattern, mode purity and beam collimation by means of a 3D printed dielectric lens. The results with the lens yield a crosstalk of β8 dB for between modes 1 and β1, and β11.4 dB for between modes 2 and β2. We suggest a mode multiplexer architecture that is expected to further reduce the crosstalk for each mode. An additional loss of 4.2 dB is incurred with the SPPs inserted into the communication link, which is undesirable for obtaining reliable LTE-based communications. Thus, we suggest: using lower loss materials, seeking ways to reduce material interface reflections or alternative ways of OAM multiplexing to realize a viable OAM multiplexed radio system
A versatile fluorescence lifetime imaging system for scanning large areas with high time and spatial resolution
"Published in SPIE Proceedings Vol. 9286"We present a flexible fluorescence lifetime imaging device which can be employed to scan large sample areas with a spatial resolution adjustable from many micrometers down to sub-micrometers and a temporal resolution of 20 picoseconds. Several different applications of the system will be presented including protein microarrays analysis, the scanning of historical samples, evaluation of solar cell surfaces and nanocrystalline organic crystals embedded in electrospun polymeric nanofibers. Energy transfer processes within semiconductor quantum dot superstructures as well as between dye probes and graphene layers were also investigated.This work was financially supported by the European Regional Development Fund (ERDF) through Programa Operacional Factores de Competitividade (COMPETE: FCOMP-01-0124-FEDER-014628) and the Portuguese Fundacao para a Ciencia e Tecnologia (FCT) through the projects "Functional structuring, inter-particle interaction and energy transfer in ensembles of nanocrystal dots" (PTDC/FIS/113199/2009), Ultra-fast spectroscopy on the dynamics and relaxation of Dirac electrons in graphene" (PTDC/FIS/101434/ 2008) and "Low dimensional nanostructures for nonlinear optical applications" PTDC/CTmNAN/114269/2009
Π‘ΠΈΡΡΠ΅ΠΌΠ½ΠΎ-ΡΡΠ½ΠΊΡΠΈΠΎΠ½Π°Π»ΡΠ½ΡΠΉ ΠΏΠΎΠ΄Ρ ΠΎΠ΄ ΠΊ ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠ΅Π½ΠΈΡ ΠΊΠΎΠΌΠΌΡΠ½Π°Π»ΡΠ½ΡΠΌΠΈ ΡΡΠ»ΡΠ³Π°ΠΌΠΈ
Purpose: the purpose of the article consists in statement of management approach to development of utilities supply processes based on conflict situations decision β making search. It had appeared in the period of the transition from the planned and directive management to market development. Methods: the research methodology is based on the system analysis of full life cycle processes functioning, forecasting of complex systems development, mathematical modeling of processes of services supply and innovative and investment projects modeling as well as development of supplying services processes. Results: the results of the work are concentrated in the presentation of systemic-functional approach to managing the development of processes of municipal services, able to resolve conflict situations in this sphere. Conclusions and Relevance: the traditional management approach on the basis of elimination of "bottlenecks" and emergencies prevailing within planned and directive system at its transformation in the market conditions has led to accumulation of conflict situations and unsolvable problems. The offered systemic-functional approach based on forecasting of full life cycle of the modernized processes and the services providing systems allows to consider costs of modernization, prime cost and quality of the rendered services.Β Π¦Π΅Π»Ρ: Π¦Π΅Π»Ρ ΡΡΠ°ΡΡΠΈ ΡΠΎΡΡΠΎΠΈΡ Π² ΠΈΠ·Π»ΠΎΠΆΠ΅Π½ΠΈΠΈ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Π° ΠΊ ΡΠΏΡΠ°Π²Π»Π΅Π½ΠΈΡ ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ΠΌ ΠΏΡΠΎΡΠ΅ΡΡΠΎΠ² ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠ΅Π½ΠΈΡ ΠΊΠΎΠΌΠΌΡΠ½Π°Π»ΡΠ½ΡΠΌΠΈ ΡΡΠ»ΡΠ³Π°ΠΌΠΈ, ΠΎΡΠ½ΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ Π½Π° ΠΏΠΎΠΈΡΠΊΠ΅ ΡΠ°Π·ΡΠ΅ΡΠ΅Π½ΠΈΡ ΠΊΠΎΠ½ΡΠ»ΠΈΠΊΡΠ½ΡΡ
ΡΠΈΡΡΠ°ΡΠΈΠΉ, ΡΠ»ΠΎΠΆΠΈΠ²ΡΠΈΡ
ΡΡ ΠΏΡΠΈ ΠΏΠ΅ΡΠ΅Ρ
ΠΎΠ΄Π΅ ΠΎΡ ΠΏΠ»Π°Π½ΠΎΠ²ΠΎ-Π΄ΠΈΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΡΠΏΡΠ°Π²Π»Π΅Π½ΠΈΡ ΠΊ ΠΌΠ΅ΡΠΎΠ΄Π°ΠΌ ΡΠΏΡΠ°Π²Π»Π΅Π½ΠΈΡ ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ΠΌ Π½Π° ΡΡΠ½ΠΎΡΠ½ΠΎΠΉ ΠΎΡΠ½ΠΎΠ²Π΅ . ΠΠ΅ΡΠΎΠ΄ΠΎΠ»ΠΎΠ³ΠΈΡ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ ΡΠ°Π±ΠΎΡΡ: ΠΠ΅ΡΠΎΠ΄ΠΎΠ»ΠΎΠ³ΠΈΡ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π±Π°Π·ΠΈΡΡΠ΅ΡΡΡ Π½Π° ΡΠΈΡΡΠ΅ΠΌΠ½ΠΎΠΌ Π°Π½Π°Π»ΠΈΠ·Π΅ ΠΏΠΎΠ»Π½ΠΎΠ³ΠΎ ΠΆΠΈΠ·Π½Π΅Π½Π½ΠΎΠ³ΠΎ ΡΠΈΠΊΠ»Π° ΡΡΠ½ΠΊΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΏΡΠΎΡΠ΅ΡΡΠΎΠ², ΠΏΡΠΎΠ³Π½ΠΎΠ·ΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΡΠ»ΠΎΠΆΠ½ΡΡ
ΡΠΈΡΡΠ΅ΠΌ, ΠΌΠ°ΡΠ΅ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠΌ ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ ΠΏΡΠΎΡΠ΅ΡΡΠΎΠ² ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠ΅Π½ΠΈΡ ΡΡΠ»ΡΠ³. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΡΠ°Π±ΠΎΡΡ: Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΡΠ°Π±ΠΎΡΡ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠΈΡΡΡΡΡΡ Π² ΠΈΠ·Π»ΠΎΠΆΠ΅Π½ΠΈΠΈ ΡΠΈΡΡΠ΅ΠΌΠ½ΠΎ-ΡΡΠ½ΠΊΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Π° ΠΊ ΡΠΏΡΠ°Π²Π»Π΅Π½ΠΈΡ ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ΠΌ ΠΏΡΠΎΡΠ΅ΡΡΠΎΠ² ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠ΅Π½ΠΈΡ ΠΊΠΎΠΌΠΌΡΠ½Π°Π»ΡΠ½ΡΠΌΠΈ ΡΡΠ»ΡΠ³Π°ΠΌΠΈ, ΡΠΏΠΎΡΠΎΠ±Π½ΠΎΠΌΡ ΡΠ°Π·ΡΠ΅ΡΠΈΡΡ ΠΊΠΎΠ½ΡΠ»ΠΈΠΊΡΠ½ΡΠ΅ ΡΠΈΡΡΠ°ΡΠΈΠΈ Π² Π΄Π°Π½Π½ΠΎΠΉ ΡΡΠ΅ΡΠ΅. ΠΡΠ²ΠΎΠ΄Ρ: Π’ΡΠ°Π΄ΠΈΡΠΈΠΎΠ½Π½ΡΠΉ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄ ΠΊ ΡΠΏΡΠ°Π²Π»Π΅Π½ΠΈΡ Π½Π° ΠΎΡΠ½ΠΎΠ²Π΅ ΡΡΡΡΠ°Π½Π΅Π½ΠΈΡ Β«ΡΠ·ΠΊΠΈΡ
ΠΌΠ΅ΡΡΒ» ΠΈ Π°Π²Π°ΡΠΈΠΉΠ½ΡΡ
ΡΠΈΡΡΠ°ΡΠΈΠΉ, ΠΏΡΠ΅ΠΎΠ±Π»Π°Π΄Π°Π²ΡΠΈΠΉ Π² ΡΠ°ΠΌΠΊΠ°Ρ
ΠΏΠ»Π°Π½ΠΎΠ²ΠΎ-Π΄ΠΈΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ ΠΏΡΠΈ Π΅Π³ΠΎ ΡΡΠ°Π½ΡΡΠΎΡΠΌΠ°ΡΠΈΠΈ Π² ΡΡΠ»ΠΎΠ²ΠΈΡΡ
ΡΡΠ½ΠΎΡΠ½ΡΡ
ΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΠΉ ΠΏΡΠΈΠ²Π΅Π» ΠΊ Π½Π°ΠΊΠΎΠΏΠ»Π΅Π½ΠΈΡ ΠΊΠΎΠ½ΡΠ»ΠΈΠΊΡΠ½ΡΡ
ΡΠΈΡΡΠ°ΡΠΈΠΉ ΠΈ Π½Π΅ΡΠ°Π·ΡΠ΅ΡΠΈΠΌΡΡ
ΠΏΡΠΎΠ±Π»Π΅ΠΌ. ΠΡΠ΅Π΄Π»Π°Π³Π°Π΅ΠΌΡΠΉ ΡΠΈΡΡΠ΅ΠΌΠ½ΠΎ-ΡΡΠ½ΠΊΡΠΈΠΎΠ½Π°Π»ΡΠ½ΡΠΉ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄, ΠΎΡΠ½ΠΎΠ²Π°Π½Π½ΡΠΉ Π½Π° ΠΏΡΠΎΠ³Π½ΠΎΠ·ΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ ΠΏΠΎΠ»Π½ΠΎΠ³ΠΎ ΠΆΠΈΠ·Π½Π΅Π½Π½ΠΎΠ³ΠΎ ΡΠΈΠΊΠ»Π° ΠΌΠΎΠ΄Π΅ΡΠ½ΠΈΠ·ΠΈΡΡΠ΅ΠΌΡΡ
ΠΏΡΠΎΡΠ΅ΡΡΠΎΠ² ΠΈ ΡΠΈΡΡΠ΅ΠΌ ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠ΅Π½ΠΈΡ ΡΡΠ»ΡΠ³Π°ΠΌΠΈ, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ ΡΠΎΠ³Π»Π°ΡΠΎΠ²Π°Π½Π½ΠΎ ΡΡΠΈΡΡΠ²Π°ΡΡ Π·Π°ΡΡΠ°ΡΡ Π½Π° ΠΌΠΎΠ΄Π΅ΡΠ½ΠΈΠ·Π°ΡΠΈΡ, ΡΠ΅Π±Π΅ΡΡΠΎΠΈΠΌΠΎΡΡΡ ΠΈ ΠΊΠ°ΡΠ΅ΡΡΠ²ΠΎ ΠΎΠΊΠ°Π·Π°Π½Π½ΡΡ
ΡΡΠ»ΡΠ³.
Ferroelectric nanofibers with an embedded optically nonlinear benzothiazole derivative
We report measurements of the molecular first hyperpolarizability, thermal stability, photophysical, piezoelectric and ferroelectric properties of a benzothiazole derivative bearing an arylthiophene Ο-conjugated bridge both in solution and when embedded into a poly (L-lactic acid) (PLLA) matrix in the form of electrospun fibers with an average diameter of roughly 500 nm. The embedded nanocrystalline phenylthienyl-benzothiazole derivative, with crystal sizes of about 1.4 nm resulted in a good piezoelectric response from these functionalized electrospun fibers, indicative of a polar crystalline structure.Fundação para a CiΓͺncia e a Tecnologia (FCT
Trends in the epidemiology of diabetic retinopathy in Russian Federation according to the Federal Diabetes Register (2013β2016)
Background: Diabetic retinopathy (DR) is one of the most common causes of blindness in patients with diabetes mellitus (DM) that is why its necessary to study the epidemiological characteristics of this complication.
Aims: The aim of the study was to evaluate the epidemiological characteristics of DR and blindness in adult patients with type 1 (T1) and 2 (T2) diabetes in Russian Federation (RF) for period 201316years.
Materials and methods: Database of Federal Diabetes register, 81st regions included in the online register. Indicators were estimated per 10,000 adult DM patients (18years).
Results: In 2016 the DR prevalence in RF was T1 38,3%, T2 15,0%, with marked interregional differences: 2,666,1%, 1,146,4%, respectively. The DR prevalence within 20132016 years was: T1 3830,93805,6; T2 1586,01497,0. Trend of new DR cases/per year increased: T1 153,2187,8; T2 99,7114,9. The structure of new cases of DR in 2016: non-proliferative stage (T1 71,4%, T2 80,3%), pre-proliferative stage 16,4%, 13,8%, proliferative 12,1%, 5,8%, terminal 0,2%, 0,1%, respectively, these data indicated the earlier detection of DR. The mean age of DR diagnosis increased: T1 by 1,2 years, T2 by 2,6. The average DM duration of DR determine increased T1 9,613,1 years, T2 6,09,1. The prevalence of blindness tends to decrease: T1 92,390,8; T2 15,415,2/10.000 DM adults. The amount of new cases of blindness/per year increased: T1 4,34,6; T2 1,21,4. The mean age of blindness increased: T1 39,141,6 years, T2 64,467,4; the mean duration of diabetes before blindness occur (from the time of DM diagnosis) increased: T1 20,221,2 years, in T2 10,711,3. We observed growth of DR treatment (laser surgery, vitrectomy, anti-VEGF medication) but the frequency of use in T2 patients is about 2 times less than in T1.
Conclusions: There was a decrease in the overall incidence of eye damage in diabetes (DR and blindness) in the analyzed period in RF. DR and blindness develops at advanced age and with a longer duration of diabetes. As the main directions of eye care development in diabetes it is necessary to standardize primary care in the regions, to unify the examination algorithms and methods of early diagnostic, to increase the continuity and interaction of endocrinologists and ophthalmologists in managing patients with diabetes in order to prevent the development of new cases of vision loss
Measurement-induced entanglement and teleportation on a noisy quantum processor
Measurement has a special role in quantum theory: by collapsing the
wavefunction it can enable phenomena such as teleportation and thereby alter
the "arrow of time" that constrains unitary evolution. When integrated in
many-body dynamics, measurements can lead to emergent patterns of quantum
information in space-time that go beyond established paradigms for
characterizing phases, either in or out of equilibrium. On present-day NISQ
processors, the experimental realization of this physics is challenging due to
noise, hardware limitations, and the stochastic nature of quantum measurement.
Here we address each of these experimental challenges and investigate
measurement-induced quantum information phases on up to 70 superconducting
qubits. By leveraging the interchangeability of space and time, we use a
duality mapping, to avoid mid-circuit measurement and access different
manifestations of the underlying phases -- from entanglement scaling to
measurement-induced teleportation -- in a unified way. We obtain finite-size
signatures of a phase transition with a decoding protocol that correlates the
experimental measurement record with classical simulation data. The phases
display sharply different sensitivity to noise, which we exploit to turn an
inherent hardware limitation into a useful diagnostic. Our work demonstrates an
approach to realize measurement-induced physics at scales that are at the
limits of current NISQ processors
Systemic-Functional Approach to Utilities Supplys
Purpose: the purpose of the article consists in statement of management approach to development of utilities supply processes based on conflict situations decision β making search. It had appeared in the period of the transition from the planned and directive management to market development. Methods: the research methodology is based on the system analysis of full life cycle processes functioning, forecasting of complex systems development, mathematical modeling of processes of services supply and innovative and investment projects modeling as well as development of supplying services processes. Results: the results of the work are concentrated in the presentation of systemic-functional approach to managing the development of processes of municipal services, able to resolve conflict situations in this sphere. Conclusions and Relevance: the traditional management approach on the basis of elimination of "bottlenecks" and emergencies prevailing within planned and directive system at its transformation in the market conditions has led to accumulation of conflict situations and unsolvable problems. The offered systemic-functional approach based on forecasting of full life cycle of the modernized processes and the services providing systems allows to consider costs of modernization, prime cost and quality of the rendered services
A Novel Functional CTL Avidity/Activity Compartmentalization to the Site of Mucosal Immunization Contributes to Protection of Macaques against Simian/Human Immunodeficiency Viral Depletion of Mucosal CD4 +
Recombinant Human Interleukin-2 Corrects NK Cell Phenotype and Functional Activity in Patients with Post-COVID Syndrome
Post-COVID syndrome develops in 10β20% of people who have recovered from COVID-19 and it is characterized by impaired function of the nervous, cardiovascular, and immune systems. Previously, it was found that patients who recovered from infection with the SARS-CoV-2 virus had a decrease in the number and functional activity of NK cells. The aim of the study was to assess the effectiveness of recombinant human IL-2 (rhIL-2) administered to correct NK cell phenotype and functional activity in patients with post-COVID syndrome. Patients were examined after 3 months for acute COVID-19 of varying severity. The phenotype of the peripheral blood NK cells was studied by flow cytometry. It was found that disturbances in the cell subset composition in patients with post-COVID syndrome were characterized by low levels of mature (p = 0.001) and cytotoxic NK cells (p = 0.013), with increased release of immature NK cells (p = 0.023). Functional deficiency of NK cells in post-COVID syndrome was characterized by lowered cytotoxic activity due to the decreased count of CD57+ (p = 0.001) and CD8+ (p < 0.001) NK cells. In the treatment of patients with post-COVID syndrome with recombinant IL-2, peripheral blood NK cell count and functional potential were restored. In general, the effectiveness of using rhIL-2 in treatment of post-COVID syndrome has been proven in patients with low levels of NK cells
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