14 research outputs found
Can We See PIP3and Hydrogen Peroxide with a Single Probe?
Get PDFA genetically encoded sensor for parallel measurements of phosphatidylinositol 3-kinase activity and hydrogen
peroxide (H2O2) levels (termed PIP-SHOW) was developed. Upon elevation of local phosphatidylinositol 3,4,5-
trisphosphate (PIP3) concentration, the sensor translocates from the cytosol to the plasma membrane, while a
ratiometric excitation change rapidly and simultaneously reports changes in the concentration of H2O2. The
dynamics of PIP3 and H2O2 generation were monitored in platelet-derived growth factor-stimulated fibroblasts
and in T-lymphocytes after formation of an immunological synapse. We suggest that PIP-SHOW can serve as a
prototype for many fluorescent sensors with combined readouts
Splitting of separatrices, scattering maps, and energy growth for a billiard inside a time-dependent symmetric domain close to an ellipse
No full text
Spinor-helicity formalism for massless fields in AdS4 III: contact four-point amplitudes
No full textUltrafast Photoconductivity of Graphene Nanoribbons and Carbon Nanotubes
No full textJensen SA, Ulbricht R, Narita A, et al. Ultrafast Photoconductivity of Graphene Nanoribbons and Carbon Nanotubes. Nano Letters. 2013;13(12):5925-5930
