82 research outputs found

    Hamartomas, teratomas and teratocarcinosarcomas of the head and neck: Report of 3 new cases with clinico-pathologic correlation, cytogenetic analysis, and review of the literature

    Get PDF
    <p>Abstract</p> <p>Background</p> <p>Germ-cell tumors (GCT) are a histologically and biologically diverse group of neoplasms which primarily occur in the gonads but also develop at different extragonadal sites in the midline of the body. The head and neck region including the upper respiratory tract is a very rare location for such tumors in both children and adults, which can cause diagnostic and therapeutic difficulties.</p> <p>Methods</p> <p>We describe here two new cases of multilineage tumors including sinonasal teratocarcinosarcoma [SNTCS], and congenital oronasopharyngeal teratoma (epignathus) and compare their features with those of a new case of a rare salivary gland anlage tumor [SGAT], an entity for which the pathogenesis is unclear (i.e. hamartoma versus neoplasm). We correlate their presenting clinico-pathological features and compare histologic and cytogenetic features in an attempt to elucidate their pathogenesis and biologic potentials.</p> <p>Results and discussion</p> <p>Cytogenetic analysis revealed chromosomal abnormalities only in the case of SNTCS that showed trisomy 12 and 1p deletion. Both cytogenetic abnormalities are characteristically present in malignant germ cell tumors providing for the first time evidence that this rare tumor type indeed might represent a variant of a germ cell neoplasm. The SGAT and epignathus carried no such cytogenetic abnormalities, in keeping with their limited and benign biologic potential.</p> <p>Conclusion</p> <p>The comparison of these three cases should serve to emphasize the diversity of multilineage tumors (hamartomas and GCT) of the upper respiratory tract in regards to their biology, age of presentation and clinical outcomes. Malignant tumors of germ cell origins are more likely to affect adults with insidious symptom development, while benign tumors can nevertheless cause dramatic clinical symptoms which, under certain circumstances, can be fatal.</p

    Carbon-nitrogen interactions in European forests and semi-natural vegetation - Part 1: Fluxes and budgets of carbon, nitrogen and greenhouse gases from ecosystem monitoring and modelling

    Get PDF
    The impact of atmospheric reactive nitrogen (Nr_{r}) deposition on carbon (C) sequestration in soils and biomass of unfertilized, natural, semi-natural and forest ecosystems has been much debated. Many previous results of this dC/dN response were based on changes in carbon stocks from periodical soil and ecosystem inventories, associated with estimates of Nr_{r} deposition obtained from large-scale chemical transport models. This study and a companion paper (Flechard et al., 2020) strive to reduce uncertainties of N effects on C sequestration by linking multi-annual gross and net ecosystem productivity estimates from 40 eddy covariance flux towers across Europe to local measurement-based estimates of dry and wet Nr_{r} deposition from a dedicated collocated monitoring network. To identify possible ecological drivers and processes affecting the interplay between C and Nr_{r} inputs and losses, these data were also combined with in situ flux measurements of NO, N2_{2}O and CH4_{4} fluxes; soil NO3_{3}̅ leaching sampling; and results of soil incubation experiments for N and greenhouse gas (GHG) emissions, as well as surveys of available data from online databases and from the literature, together with forest ecosystem (BASFOR) modelling. Multi-year averages of net ecosystem productivity (NEP) in forests ranged from -70 to 826 gCm−2^{-2} yr−1^{-1} at total wet+dry inorganic Nr_{r} deposition rates (Ndep_{dep}) of 0.3 to 4.3 gNm−2^{-2} yr−1^{-1} and from -4 to 361 g Cm−2^{-2} yr−1^{-1} at Ndep_{dep} rates of 0.1 to 3.1 gNm−2^{-2} yr−1^{-1} in short semi-natural vegetation (moorlands, wetlands and unfertilized extensively managed grasslands). The GHG budgets of the forests were strongly dominated by CO2_{2} exchange, while CH4_{4} and N2_{2}O exchange comprised a larger proportion of the GHG balance in short semi-natural vegetation. Uncertainties in elemental budgets were much larger for nitrogen than carbon, especially at sites with elevated Ndep_{dep} where Nr_{r} leaching losses were also very large, and compounded by the lack of reliable data on organic nitrogen and N2_{2} losses by denitrification. Nitrogen losses in the form of NO, N2_{2}O and especially NO3_{3}̅ were on average 27%(range 6 %–54 %) of Ndep_{dep} at sites with Ndep_{dep} 3 gNm−2^{-2} yr−1^{-1}. Such large levels of Nr_{r} loss likely indicate that different stages of N saturation occurred at a number of sites. The joint analysis of the C and N budgets provided further hints that N saturation could be detected in altered patterns of forest growth. Net ecosystem productivity increased with Nr_{r} deposition up to 2–2.5 gNm−2^{-2} yr−1^{-1}, with large scatter associated with a wide range in carbon sequestration efficiency (CSE, defined as the NEP = GPP ratio). At elevated Ndep_{dep} levels (> 2.5 gNm−2^{-2} yr−1^{-1}), where inorganic Nr_{r} losses were also increasingly large, NEP levelled off and then decreased. The apparent increase in NEP at low to intermediate Ndep_{dep} levels was partly the result of geographical cross-correlations between Ndep_{dep} and climate, indicating that the actual mean dC/dN response at individual sites was significantly lower than would be suggested by a simple, straightforward regression of NEP vs. Ndep_{dep}

    Potentials of small, lightweight and low cost Multi-Echo Laser Scanners for detecting Grape Berries

    No full text
    Mobile sensor devices offer great opportunities for automatic scene analysis and object recognition. Nowadays a new generation of ranging devices is available, like laser scanners which are small and light weighted. Concerning these improvements specific applications can be tackled. In this contribution we focus on vineyard monitoring for detecting and counting grape berries with a small, lightweight and low cost multi-echo laser scanner. Therefore a Hokuyo UTM-30LX-EW laser range finder is utilized for capturing the data in close range up to 1m. In order to process the data the following methodology is proposed: after smoothing and morphological techniques are applied on the laserscanning intensity and range images the number of visible grape berries is determined from the resulting segments. The approach performs with a detection accuracy of above 84%. The results reveal the high potential of such close range ranging devices for locating and counting grape berries. Thus, the methodology provides practical support for viticulture applications

    Potentials of small, lightweight and low cost Multi-Echo Laser Scanners for detecting Grape Berries

    No full text
    Mobile sensor devices offer great opportunities for automatic scene analysis and object recognition. Nowadays a new generation of ranging devices is available, like laser scanners which are small and light weighted. Concerning these improvements specific applications can be tackled. In this contribution we focus on vineyard monitoring for detecting and counting grape berries with a small, lightweight and low cost multi-echo laser scanner. Therefore a Hokuyo UTM-30LX-EW laser range finder is utilized for capturing the data in close range up to 1m. In order to process the data the following methodology is proposed: after smoothing and morphological techniques are applied on the laserscanning intensity and range images the number of visible grape berries is determined from the resulting segments. The approach performs with a detection accuracy of above 84%. The results reveal the high potential of such close range ranging devices for locating and counting grape berries. Thus, the methodology provides practical support for viticulture applications
    • 

    corecore