Grappling with COVID-19 by imposing and lifting nonpharmaceutical interventions in Sri Lanka: A modeling perspective

The imposition and lifting of non-pharmaceutical interventions (NPIs) to avert the COVID19 pandemic have gained popularity worldwide and will continue to be enforced until herd immunity is achieved. We developed a linear regression model to ascertain the nexus between the time-varying reproduction number averaged over a time window of six days (Rts) and seven NPIs: contact tracing, quarantine efforts, social distancing and health checks, hand hygiene, wearing of facemasks, lockdown and isolation, and health-related supports. Our analysis suggests that the second wave that emerged in Sri Lanka in early October 2020 continued despite numerous NPIs. The model indicates that the most effective single NPI was lockdown and isolation. Conversely, the least effective individual NPIs were hand hygiene and wearing of facemasks. The model also demonstrates that to mitigate the second wave to a satisfactory level (Rts\u3c1), the best single NPI was the contact tracing with stringent imposition (% of improvement of Rts was 69.43 against the base case). By contrast, the best combination of two NPIs was the lockdown & isolation with health-related supports (% of improvement was 31.92 against the base case). As such, many health authorities worldwide can use this model to successfully strategize the imposition and lifting of NPIs for averting the COVID-19 pandemic

Mooring Chain Climbing Robot For Ndt Inspection Applications

Inspection of mooring chains is a dangerous and costly procedure covering inspection above and below the waterline. The paper presents initial results from the RIMCAW project which was aimed at designing and building an inspection robot able to climb mooring chains and deploy NDT technologies for scanning individual links thereby to detecting critical defects. The paper focuses on the design and realisation of the inch worm type novel crawler developed and tested in the TWI Middlesbrough water tank

The Legal Framework for Design Liability in Building Information Modelling

Building Information Modelling (BIM) is a solution to achieve productivity, efficiency, life cycle enhancement and sustainability in the construction industry. It also promotes the two symbiotic factors information sharing and collaborative approach among the professionals. Transference from the conventional practice to BIM will make the design liabilities change and create legal uncertainties among the professionals. This was expected to be acting as an obstacle to achieve the desires in BIM’s wider adoption and a suitable legal framework was found to be necessary. The solutions for the legal uncertainties arising from the new environment needs to be formulated and on the other hand in order to adopt BIM in an effective manner it requires identifying of these legal uncertainties and provides a clear vision for the client and the design team on how they should work in the changed environment. With this prime intention, this research was conducted adopting mixture of legal and scientific research methods. Initially preliminary literature synthesis was carried out which discussed the present legal environment with the expected change through BIM. The legal analysis was carried out following the flexible iterative style where the researchers’ opinion blends with the experiences from primary sources of law to build up the tentative hypothesis. Through semi structured interviews with a group of experts representing different proficiencies in the construction industry, this tentative hypothesis was tested; the collected data from construction industry experts were subjected to content analysis based on opinions and suggestions, these findings were then interpreted to identify the suitable legal framework. The legal framework which was identified includes the preventive mechanism of negligent acts, liabilities of the human factor, process and enforceability, actions, proposed provisions and suggestion. Hence, this framework is recommended to be implemented in the BIM environment.International Council for Research and Innovation in Building and Construction (CIB

Urban Watercourses in Peril: Implications of Phthalic Acid Esters on Aquatic Ecosystems Caused by Urban Sprawl

Urban sprawl worldwide warrants the use of large quantities of industrial and household products containing phthalic acid esters (PAEs) resulting in adverse impacts on the quality of aquatic life in urban watercourses. The presence of six PAEs (dimethyl phthalate (DMP), diethyl phthalate (DEP), di(n-butyl) phthalate (DBP), benzyl butyl phthalate (BBP), bis(2-ethylhexyl) phthalate (DEHP), and di(n-octyl) phthalate (DnOP)) in 22 shallow urban watercourses in Colombo and suburbs of Sri Lanka was investigated. The average concentrations of DEP, DBP, BBP, and DEHP in all watercourses varied between 2.5–265.0, 1.0–32.0, 61–108, and 12–165 µg/L, respectively. DMP and DnOP were below the limits of quantification (DMP-0.5 µg/L, DnOP-1.0 µg/L) for all watercourses. DEHP was the most abundant PAE in many watercourses. The significant factors affecting the ubiquitous presence of PAEs in watercourses are the inherent properties of each PAE, presence of industrial and household products with great potential for the migration of PAEs in the sub-catchments, and quality of the receiving water. The contamination levels of PAEs in most of the watercourses are alarmingly high, as evidenced by higher concentrations of DEHP and DBP than those of Canadian permissible levels for the protection of aquatic life (16 and 19 µg/L). This study was the first effort in Sri Lanka to investigate the presence of PAEs in urban watercourses

Mooring Chain Climbing Robot For Ndt Inspection Applications

Inspection of mooring chains is a dangerous and costly procedure covering inspection above and below the waterline. The paper presents initial results from the RIMCAW project which was aimed at designing and building an inspection robot able to climb mooring chains and deploy NDT technologies for scanning individual links thereby to detecting critical defects. The paper focuses on the design and realisation of the inch worm type novel crawler developed and tested in the TWI Middlesbrough water tank

Early identification of acute kidney injury in Russell's viper (Daboia russelii) envenoming using renal biomarkers.

BACKGROUND:Acute kidney injury (AKI) is a major complication of snake envenoming, but early diagnosis remains problematic. We aimed to investigate the time course of novel renal biomarkers in AKI following Russell's viper (Daboia russelii) bites. METHODOLOGY/PRINCIPAL FINDINGS:We recruited a cohort of patients with definite Russell's viper envenoming and collected serial blood and urine samples on admission (<4h post-bite), 4-8h, 8-16h, 16-24h, 1 month and 3 months post-bite. AKI stage (1-3) was defined using the Acute Kidney Injury Network criteria. AKI stages (1-3) were defined by the Acute Kidney Injury Network (AKIN) criteria. There were 65 Russell's viper envenomings and 49 developed AKI: 24 AKIN stage 1, 13 stage 2 and 12 stage 3. There was a significant correlation between venom concentrations and AKI stage (p = 0.007), and between AKI stage and six peak biomarker concentrations. Although most biomarker concentrations were elevated within 8h, no biomarker performed well in diagnosing AKI <4h post-bite. Three biomarkers were superior to serum creatinine (sCr) in predicting AKI (stage 2/3) 4-8h post-bite: serum cystatin C (sCysC) with an area under the receiver operating curve (AUC-ROC), 0.78 (95%CI:0.64-0.93), urine neutrophil gelatinase-associated lipocalin (uNGAL), 0.74 (95%CI:0.59-0.87) and urine clusterin (uClu), 0.81 (95%CI:0.69-0.93). No biomarker was better than sCr after 8h. Six other urine biomarkers urine albumin, urine beta2-microglobulin, urine kidney injury molecule-1, urine cystatin C, urine trefoil factor-3 and urine osteopontin either had minimal elevation, and/or minimal prediction for AKI stage 2/3 (AUC-ROC<0.7). CONCLUSIONS/SIGNIFICANCE:AKI was common and sometimes severe following Russell's viper bites. Three biomarkers uClu, uNGAL and sCysC, appeared to become abnormal in AKI earlier than sCr, and may be useful in early identification of envenoming

Design and prototype of a magnetic adhesion tracked-wheel robotic platform for mooring chain inspection

London South Bank Innovation Centre (LSBIC); National Structural Integrity Research Centre (NSIRC) and TWI (NDT department), Cambridge; InnovateU