PHYSICAL ACTIVITY LEVEL DOES NOT INFLUENCE THE NEUROMUSCULAR FATIGUE IN ADULTS

Introduction: Fatigue during voluntary muscle contractions is a complex and multifactorial phenomenon associated with central changes and adaptations of the neuromuscular system. Objective: The purpose of this study was to evaluate the fatigue induced by intermittent successive extension of the knee between active and inactive university students. Method: Twenty healthy men (≥18 years), voluntarily participated in this study. To determine the maximum voluntary isometric contraction (MVIC) of the knee extensors muscle group, three sets of isometric contractions of knee extension were performed for five seconds with five minutes of rest between sets. The fatigue protocol consisted of 10 sets of 10 maximal concentric contractions of the extensor on the right knee, performed at 75% of MVIC with an interval of 45". Results: Significant reductions were observed (p<0.01), both in isometric strength (-34±4%) and the dynamic strength (-40 ± 3%). In addition, the slope of relationship strength x repetition was -0.79±0.07 Nm/repetitions and the magnitude of the effect reached -8.90. Conclusion: The protocol was useful to induce peripheral fatigue, although muscle strength is greater in the active group. In both isometric and dynamic action, muscle fatigue did not differ between groups

BIN1 Localizes the L-Type Calcium Channel to Cardiac T-Tubules

Cardiac tubular-like membrane invaginations contain the membrane scaffolding protein BIN1, which tethers dynamic microtubules that deliver calcium channels directly to T-tubule membrane

Blood pressure control at rest and during exercise in obese children and adults

The hemodynamic responses to exercise have been studied to a great extent over the past decades, and an exaggerated blood pressure response during an acute exercise bout has been considered as an indicator of cardiovascular risk. Obesity is a major factor influencing the blood pressure response to exercise since evidence indicates that the arterial pressure response to exercise is exacerbated in obese compared with lean adults. Signs of augmented responses (such as an exaggerated blood pressure response) to physical exertion appear early in life (from the prepubertal years) in obese individuals. Understanding the mechanisms that drive the altered hemodynamic responses during exercise in obese individuals and prevent the progression to hypertension is vitally important. This paper focuses on the evidence linking obesity with alterations of the autonomic nervous system and discusses the potential mechanisms and consequences of the altered sympathetic nervous system behavior in obese individuals at rest and during exercise. Furthermore, this paper presents the alterations in the reflex regulatory mechanisms (&quot;exercise pressor reflex&quot; and baroreflex) in obese children and adults and addresses the effects of training on obesity-related disturbances. © 2012 Konstantina Dipla et al

Whole-body vibration training improves flexibility, strength profile of knee flexors, and hamstrings-to-quadriceps strength ratio in females

Objectives: Short-term whole-body vibration training (WBVT) has emerged as an exercise method for improving neuromuscular performance and has been proposed for injury prevention and rehabilitation. This study investigated the effects of a short-term (<= 2 months) WBVT program using a side-to-side vibration on: (i) strength profile of knee extensors (ME) and flexors (KF), (ii) "functional" hamstrings-to-quadriceps ratio (ECCKF/CONKE), (iii) flexibility and (iv) vertical jumping performance (VJ). Furthermore, we explored the retention of performance gains 21 days following WBVT. Design: Randomized-controlled trial. Methods: Twenty-six moderately active females (20.40 +/- 0.27 years) were assigned to a vibration (VG) or a control group (CG). The short-term WBVT program consisted of sixteen-sessions on a side-to-side vibration platform (frequency: 25 Hz, amplitude: 6 mm, 2 sets x 5 min). Isokinetic and isometric peak torque of KE and KF, ECCKF/CONKE, flexibility, and VJ were measured pre, 2 days post, and 21 days following the cessation of WBVT. Results: Post-training values of flexibility, isokinetic and isometric peak torques of KF and ECCKF/CONKE ratio were higher than pre-training values in VG (p < 0.05); however, they remained unchanged in CG. Post-training values were greater in VG vs. CG (p < 0.05). Twenty-one days following WBVT, post-training values were no longer significantly different than pre-training values. The short-term WBVT program had no effect on strength profile of KE and on VJ. Conclusions: A short-term side-to-side WBVT program improved flexibility, the strength profile of knee flexors, and the "functional" hamstrings-to-quadriceps ratio in moderately active females. Coaches and clinical practitioners should consider this type of training as an effective exercise mode for improving the strength asymmetry of reciprocal muscles at the knee joint. (C) 2012 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved

Altered hemodynamic regulation and reflex control during exercise and recovery in obese boys

The aims of the present study were to assess in obese and lean boys 1) the hemodynamic responses and baroreflex sensitivity (BRS) to isometric handgrip exercise (HG) and recovery and 2) the muscle metaboreflex-induced blood pressure response and the variables that determine this response. Twenty-seven boys (14 obese and 13 lean boys, body mass index: 29.2 ± 0.9 vs. 18.9 ± 0.3kg/m 2, respectively) participated. The testing protocol involved 3 min of baseline, 3 min of HG (30% maximum voluntary contraction), 3 min of circulatory occlusion, and 3 min of recovery. The same protocol was repeated without occlusion. At baseline, no differences were detected between groups in beat-to-beat arterial pressure (AP), heart rate (HR), and BRS; however, obese boys had higher stroke volume and lower total peripheral resistance than lean boys (P &amp;lt; 0.05). During HG, lean boys exhibited higher HR and lower BRS compared with their obese counterparts. In lean boys, BRS decreased during HG compared with baseline, whereas in obese boys, it was not significantly modified. In lean boys, TPR was elevated during HG and declined after exercise, whereas in obese boys, TPR did not significantly decrease after exercise cessation. In the postexercise period, BRS in lean boys returned to baseline, whereas an overshoot was observed in obese boys. Postexercise BRS was correlated with body mass index (R = 0.56, P &amp;lt; 0.05). Although the metaboreflex-induced increase in AP was similar between obese and lean children, it was achieved via different mechanisms: in lean children, total peripheral resistance was the main contributor to AP maintenance during the metaboreflex, whereas in obese children, stroke volume significantly contributed to AP maintenance during the metaboreflex. In conclusion, obese normotensive children demonstrated altered cardiovascular hemodynamics and reflex control during exercise and recovery. Copyright © 2010 the American Physiological Society

AGE-RELATED DIFFERENCES IN PEAK HANDGRIP STRENGTH BETWEEN WRESTLERS AND NONATHLETES DURING THE DEVELOPMENTAL YEARS

Gerodimos, V, Karatrantou, K, Dipla, K, Zafeiridis, A, Tsiakaras, N, and Sotiriadis, S. Age-related differences in peak handgrip strength between wrestlers and nonathletes during the developmental years. J Strength Cond Res 27(3): 616-623, 2013-This study examined the development of peak handgrip strength from childhood to adulthood in wrestlers (n = 122) and nonathlete controls (n = 122). The effect of hand preference on handgrip strength and the relationship of anthropometrical characteristics with handgrip strength in wrestlers and controls were also evaluated. Participants were assigned into age groups: children, young adolescents, late adolescents, and adults. Body height and mass, hand dimensions (length, span, and width), and absolute handgrip (in kilograms) were measured. Handgrip strength was similar in wrestlers and controls in the younger age groups (i.e., in children and young adolescents), whereas late adolescent and adult wrestlers exhibited significantly greater peak handgrip strength (p < 0.05) than their control peers. Nonathletes older than 15 years demonstrated an approximately 10% greater peak handgrip strength (p < 0.05) with their preferred hand compared with the nonpreferred hand. In contrast, late adolescent and adult wrestlers exhibited similar handgrip strength with both hands. Peak handgrip strength exhibited a significant linear correlation with all the anthropometric measures examined; however, a higher percentage in the variation in peak handgrip strength was explained by body height and hand length than the other anthropometric variables in both groups. In conclusion, wrestlers exhibit a sport-specific pattern of handgrip strength changes during the developmental years. Body height and hand length exhibited the strongest correlations with handgrip strength during the developmental years in wrestlers and in controls. The training adaptations of wrestling resulted in symmetrical handgrip strength development in both hands at late adolescence and adulthood. These data serve to provide a descriptive profile of handgrip strength in wrestlers, to assist both coaches and health professionals for talent selection and/or development of training programs for performance enhancement and rehabilitation

The Contribution of Stretch-Shortening Cycle and Arm-Swing to Vertical Jumping Performance in Children, Adolescents, and Adult Basketball Players

This study examined from childhood to adulthood: (1) the effects of countermovement (use of stretch-shortening cycle-SSC) and arm-swing (AS) on vertical jumping (W) performance and (2) the ability to use the SSC and AS during VJ. Male basketball players (n = 106) were divided according to their age into: children (12.0 +/- 0.23), young adolescents (14.5 +/- 0.41), old adolescents (16.9 +/- 0.27), and adults (21.9 +/- 0.32). Each participant executed three maximal squat jumps (SJ), countermovement jumps without arms (CMJ) and with arms (CMJA). The contribution of SSC and AS was calculated by the augmentation (difference and percent change) in performance between CMJ and SJ, and CMJA and CMJ, respectively. CMJA performance was significantly (p .05) among children, young and old adolescents, and adults in the percent contribution of SSC and AS to VJ performance. The variability in the contribution of SSC and AS to VJ performance was about twofold higher in children vs. adults. It appears that the ability to use the SSC and AS is not affected by the maturation process in males, trained in basketball

Reduced metaboreflex control of blood pressure during exercise in individuals with intellectual disability: A possible contributor to exercise intolerance

The aim was to investigate the hemodynamic responses to isometric handgrip exercise (HG) and examine the role of the muscle metaboreflex in the exercise pressor response in individuals with intellectual disability (IID) and non-disabled control subjects. Eleven males with mild-moderate intellectual disabilities and eleven non-disabled males performed a testing protocol involving 3-min periods of baseline, HG exercise (at 30% MVC), circulatory occlusion, and recovery. The same protocol was repeated without occlusion. At baseline, no differences were detected between groups in beat-to-beat mean arterial pressure (MAP), heart rate (HR), stroke volume, and peripheral resistance. IID were able to sustain an exercise MAP response at comparable levels to the control group exerting similar peripheral resistance; however, IID exhibited a blunted chronotropic response to HG and a diminished exercise vagal withdrawal compared to controls. During occlusion, IID exhibited a lower pressor response than their control peers, associated with a lower increase in peripheral resistance during this task. In conclusion, although intellectual disabilities can be the consequence of many different genes, IID share common deficits in the chronotropic response to exercise and a blunted metaboreflex-induced pressor response. © 2012 Elsevier Ltd