Cylinder morphology of a stretched and twisted ribbon

A rich zoology of shapes emerges from a simple stretched and twisted elastic ribbon. Despite a lot of interest, all these shape are not understood, in particular the shape that prevails at large tension and twist and that emerges from a transverse instability of the helicoid. Here, we propose a simple description for this cylindrical shape. By comparing its energy to the energy of other configurations, we are able to determine its location on the phase diagram. The theoretical predictions are in good agreement with our experimental results

A new stability results for the backward heat equation

In this paper, we regularize the nonlinear inverse time heat problem in the unbounded region by Fourier method. Some new convergence rates are obtained. Meanwhile, some quite sharp error estimates between the approximate solution and exact solution are provided. Especially, the optimal convergence of the approximate solution at t = 0 is also proved. This work extends to many earlier results in (f2,f3, hao1,Quan,tau1, tau2, Trong3,x1).Comment: 13 page

Random walks on mutual microRNA-target gene interaction network improve the prediction of disease-associated microRNAs

Background: MicroRNAs (miRNAs) have been shown to play an important role in pathological initiation, progression and maintenance. Because identification in the laboratory of disease-related miRNAs is not straightforward, numerous network-based methods have been developed to predict novel miRNAs in silico. Homogeneous networks (in which every node is a miRNA) based on the targets shared between miRNAs have been widely used to predict their role in disease phenotypes. Although such homogeneous networks can predict potential disease-associated miRNAs, they do not consider the roles of the target genes of the miRNAs. Here, we introduce a novel method based on a heterogeneous network that not only considers miRNAs but also the corresponding target genes in the network model. Results: Instead of constructing homogeneous miRNA networks, we built heterogeneous miRNA networks consisting of both miRNAs and their target genes, using databases of known miRNA-target gene interactions. In addition, as recent studies demonstrated reciprocal regulatory relations between miRNAs and their target genes, we considered these heterogeneous miRNA networks to be undirected, assuming mutual miRNA-target interactions. Next, we introduced a novel method (RWRMTN) operating on these mutual heterogeneous miRNA networks to rank candidate disease-related miRNAs using a random walk with restart (RWR) based algorithm. Using both known disease-associated miRNAs and their target genes as seed nodes, the method can identify additional miRNAs involved in the disease phenotype. Experiments indicated that RWRMTN outperformed two existing state-of-the-art methods: RWRMDA, a network-based method that also uses a RWR on homogeneous (rather than heterogeneous) miRNA networks, and RLSMDA, a machine learning-based method. Interestingly, we could relate this performance gain to the emergence of "disease modules" in the heterogeneous miRNA networks used as input for the algorithm. Moreover, we could demonstrate that RWRMTN is stable, performing well when using both experimentally validated and predicted miRNA-target gene interaction data for network construction. Finally, using RWRMTN, we identified 76 novel miRNAs associated with 23 disease phenotypes which were present in a recent database of known disease-miRNA associations. Conclusions: Summarizing, using random walks on mutual miRNA-target networks improves the prediction of novel disease-associated miRNAs because of the existence of "disease modules" in these networks

From cylindrical to stretching ridges and wrinkles in twisted ribbons

Twisted ribbons subjected to a tension exhibit a remarkably rich morphology, from smooth and wrinkled helicoids, to cylindrical or faceted patterns. These shapes are intimately related to the instability of the natural, helicoidal symmetry of the system, which generates both longitudinal and transverse stresses, thereby leading to buckling of the ribbon. In this paper, we focus on the tessellation patterns made of triangular facets. Our experimental observations are described within an "asymptotic isometry" approach that brings together geometry and elasticity. The geometry consists of parametrized families of surfaces, isometric to the undeformed ribbon in the singular limit of vanishing thickness and tensile load. The energy, whose minimization selects the favored structure among those families, is governed by the tensile work and bending cost of the pattern. This framework describes the coexistence lines in a morphological phase diagram, and determines the domain of existence of faceted structures.Comment: 5 pages, 4 figures; Supplemental material: 4 page

Supply Chain Agility and Internal and External Process Connectivity: The Impact of Supply and Product Complexity

The study attempts to analyze the impact of internal and external process connectivity on supply chain agility of manufacturing firms in Thailand. It also examines whether supply and product complexity moderates the impact of internal and external process connectivity on supply chain agility. The study relies on the questionnaire survey to collect the data. Using electronic survey, the respondents working in manager’ positions in Thailand’s manufacturing companies are targeted. Out of 250 survey questionnaires, only 173 responses were found usable with a rate of response of 57.2%. The study focuses on Thai firms because Thai manufacturing sector is one of the strongest players in the globe. The reason to select manufacturing firms is that the manufacturing firms are considered to be very crucial in global supply chains in terms of providing agility and responsiveness while delivering final products to the consumers. Supply chain agility (SCAG) is used as dependent while internal process connectivity (INPC) and external process connectivity (EXPC) are used as independent variables. Moreover, product complexity (PRCX) and supply complexity (SPCX) are used as moderating variables. Findings show that SPCX has negatively significant influence on SCAG while PRCX has insignificant effect on SCAG. INPC and EXPC have positive and significant impact on SCAG. The results state that both INPC and EXPC play vital role in attaining SCAG. The interaction effect of product term (INPC × EXPC) on SCAG is also found to be positively significant. These outcomes are in line with the process theory which states that both INPC and EXPC are significant factor that play important role in attaining SCAG. Both these processes permit companies to better respond to continuous variations

IT applications in education and Self-directed learning capacity

For differentiated teaching methods in Vietnam, educators only focus on intellectual ability which is provided in academic report cards. Overlooking psychological and cognitive factors leads to poor performance of differentiated teaching in high school in Vietnam. This application of technology in teaching helps teachers to prepare lessons quickly through available lecture templates, and at the same time take advantage of many resources such as videos, images, electronic documents, etc. help attract learners and improve teaching effectiveness

Impact of Corporate Entrepreneurship and Organizational Culture on Business Performance: The Role of Supply Chain Management

With the expanding multifaceted nature and vulnerability of worldwide inventory chains, interruption occasions are as often as possible happening in production network. Commercial condition is separated into two sorts including inner and outer business conditions. In the examination, our inward business condition is organization culture and inside business condition is supply chain performance (SCP). Therefore, the purpose of this study is to quantify the impact of organizational culture (OC), corporate entrepreneurship (CE) and its components on business performance (BP) through SCP in the non-financial sector of Thailand. Research sample comprises of 120 non-financial firms operating in Thailand. The study finds that SCP fully mediates the relationship between work reinforcement BP and time availability and BP. Whereas, SCP is found to have partial mediation in the relationship between CE BP, OC BP, management support BP, organization boundaries BP and reward reinforcement and BP. Findings of study are important for mangers in understanding and implementation of better OC which leads to CE and will ultimately enhance BP

New criteria for exponential stability of linear neutral differential systems with distributed delays

summary:We present new explicit criteria for exponential stability of general linear neutral time-varying differential systems. Particularly, our results give extensions of the well-known stability criteria reported in [3,11] to linear neutral time-varying differential systems with distributed delays