6,057 research outputs found
Notes on a collection of birds from Mindoro Island, Philippines
The 1954 Yale Peabody Museum-Silliman University Mindoro Zoological Expedition, headed by D. S. Rabor, stayed in the field from March 21 until June 7, 1954….https://elischolar.library.yale.edu/peabody_museum_natural_history_bulletin/1012/thumbnail.jp
New birds from Palawan and Culion Islands, Philippines
The Palawan Expedition of 1962 was sponsored jointly by the Yale Peabody Museum, the Entomology Section of the U. S. Army Medical Research and Development Command of the Office of the Surgeon General
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Tablet PCs in schools: Case study report: A report for Becta by the Open University
The publication provides an analysis of twelve case studies involving schools in England that were using Tablet PCs. The analysis is complemented by brief individual reports describing aspects of how each of these schools was using Tablet PCs
Polarized Redundant-Baseline Calibration for 21 cm Cosmology Without Adding Spectral Structure
21 cm cosmology is a promising new probe of the evolution of visible matter
in our universe, especially during the poorly-constrained Cosmic Dawn and Epoch
of Reionization. However, in order to separate the 21 cm signal from bright
astrophysical foregrounds, we need an exquisite understanding of our telescopes
so as to avoid adding spectral structure to spectrally-smooth foregrounds. One
powerful calibration method relies on repeated simultaneous measurements of the
same interferometric baseline to solve for the sky signal and for instrumental
parameters simultaneously. However, certain degrees of freedom are not
constrained by asserting internal consistency between redundant measurements.
In this paper, we review the origin of these "degeneracies" of
redundant-baseline calibration and demonstrate how they can source unwanted
spectral structure in our measurement and show how to eliminate that
additional, artificial structure. We also generalize redundant calibration to
dual-polarization instruments, derive the degeneracy structure, and explore the
unique challenges to calibration and preserving spectral smoothness presented
by a polarized measurement.Comment: 12 pages, 3 figures, updated to match the published MNRAS versio
Recent Changes in Irish Fertility. Quarterly Economic Commentary Special Article, May 1984
The main purpose of this paper is to provide a broad description of fertility
trends in Ireland over the last two decades. The analysis investigates in
particular whether there are regional (i.e., county) differences in relation to
the levels of fertility and how these have changed. In the final part of the paper
we discuss the likely future pattern of fertility trends and consider some
economic and social implications arising therefrom. The last-mentioned aspect
is now a matter of considerable significance since there are indications (from
the annual births total) that the general decline in fertility has escalated to
such an extent in recent years that the effects may be quite substantial and
materialise within a relatively short period of time
RATT: Rapid Annotation Transfer Tool
Second-generation sequencing technologies have made large-scale sequencing projects commonplace. However, making use of these datasets often requires gene function to be ascribed genome wide. Although tool development has kept pace with the changes in sequence production, for tasks such as mapping, de novo assembly or visualization, genome annotation remains a challenge. We have developed a method to rapidly provide accurate annotation for new genomes using previously annotated genomes as a reference. The method, implemented in a tool called RATT (Rapid Annotation Transfer Tool), transfers annotations from a high-quality reference to a new genome on the basis of conserved synteny. We demonstrate that a Mycobacterium tuberculosis genome or a single 2.5 Mb chromosome from a malaria parasite can be annotated in less than five minutes with only modest computational resources. RATT is available at http://ratt.sourceforge.net
Pandemic Paradox: Early Life H2N2 Pandemic Influenza Infection Enhanced Susceptibility to Death during the 2009 H1N1 Pandemic.
Recent outbreaks of H5, H7, and H9 influenza A viruses in humans have served as a vivid reminder of the potentially devastating effects that a novel pandemic could exert on the modern world. Those who have survived infections with influenza viruses in the past have been protected from subsequent antigenically similar pandemics through adaptive immunity. For example, during the 2009 H1N1 "swine flu" pandemic, those exposed to H1N1 viruses that circulated between 1918 and the 1940s were at a decreased risk for mortality as a result of their previous immunity. It is also generally thought that past exposures to antigenically dissimilar strains of influenza virus may also be beneficial due to cross-reactive cellular immunity. However, cohorts born during prior heterosubtypic pandemics have previously experienced elevated risk of death relative to surrounding cohorts of the same population. Indeed, individuals born during the 1890 H3Nx pandemic experienced the highest levels of excess mortality during the 1918 "Spanish flu." Applying Serfling models to monthly mortality and influenza circulation data between October 1997 and July 2014 in the United States and Mexico, we show corresponding peaks in excess mortality during the 2009 H1N1 "swine flu" pandemic and during the resurgent 2013-2014 H1N1 outbreak for those born at the time of the 1957 H2N2 "Asian flu" pandemic. We suggest that the phenomenon observed in 1918 is not unique and points to exposure to pandemic influenza early in life as a risk factor for mortality during subsequent heterosubtypic pandemics.IMPORTANCE The relatively low mortality experienced by older individuals during the 2009 H1N1 influenza virus pandemic has been well documented. However, reported situations in which previous influenza virus exposures have enhanced susceptibility are rare and poorly understood. One such instance occurred in 1918-when those born during the heterosubtypic 1890 H3Nx influenza virus pandemic experienced the highest levels of excess mortality. Here, we demonstrate that this phenomenon was not unique to the 1918 H1N1 pandemic but that it also occurred during the contemporary 2009 H1N1 pandemic and 2013-2014 H1N1-dominated season for those born during the heterosubtypic 1957 H2N2 "Asian flu" pandemic. These data highlight the heretofore underappreciated phenomenon that, in certain instances, prior exposure to pandemic influenza virus strains can enhance susceptibility during subsequent pandemics. These results have important implications for pandemic risk assessment and should inform laboratory studies aimed at uncovering the mechanism responsible for this effect
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