From Simulated Mixtures to Simulated Conversations as Training Data for End-to-End Neural Diarization

End-to-end neural diarization (EEND) is nowadays one of the most prominent research topics in speaker diarization. EEND presents an attractive alternative to standard cascaded diarization systems since a single system is trained at once to deal with the whole diarization problem. Several EEND variants and approaches are being proposed, however, all these models require large amounts of annotated data for training but available annotated data are scarce. Thus, EEND works have used mostly simulated mixtures for training. However, simulated mixtures do not resemble real conversations in many aspects. In this work we present an alternative method for creating synthetic conversations that resemble real ones by using statistics about distributions of pauses and overlaps estimated on genuine conversations. Furthermore, we analyze the effect of the source of the statistics, different augmentations and amounts of data. We demonstrate that our approach performs substantially better than the original one, while reducing the dependence on the fine-tuning stage. Experiments are carried out on 2-speaker telephone conversations of Callhome and DIHARD 3. Together with this publication, we release our implementations of EEND and the method for creating simulated conversations.Comment: Submitted to Interspeech 202

The effect of sleep quality on academic performance is mediated by Internet use time: DADOS study

Objective: The aims of the present study were to analyze the association of sleep patterns withacademic and cognitive performance in adolescents, and to test the potential mediating effectof different activities of screen media usage on this association.Methods: A sample of 269 adolescents (140 boys) aged 14 years from the baseline data of theDeporte, ADOlescencia y Salud study completed questionnaires about sleep quality, cognitiveperformance, and leisure-time sedentary behaviors. Sleep duration was objectively computedusing a wrist-worn GENEActiv accelerometer and academic performance was analyzed throughschool records.Results: Sleep quality (but not sleep duration) was associated with all the academic perfor-mance indicators (all p < 0.05). Analysis of covariance revealed higher grades among adolescentswith better sleep quality (PSQI ≤ 5; all p < 0.05). These analyses showed no differences regardingcognitive performance. Internet use time was revealed as a mediator of the association betweensleep quality and academic performance, being significant for all academic performance indi-cators (PMranging from 15.5% to 16.0%)

Multi-Stream Extension of Variational Bayesian HMM Clustering (MS-VBx) for Combined End-to-End and Vector Clustering-based Diarization

Combining end-to-end neural speaker diarization (EEND) with vector clustering (VC), known as EEND-VC, has gained interest for leveraging the strengths of both methods. EEND-VC estimates activities and speaker embeddings for all speakers within an audio chunk and uses VC to associate these activities with speaker identities across different chunks. EEND-VC generates thus multiple streams of embeddings, one for each speaker in a chunk. We can cluster these embeddings using constrained agglomerative hierarchical clustering (cAHC), ensuring embeddings from the same chunk belong to different clusters. This paper introduces an alternative clustering approach, a multi-stream extension of the successful Bayesian HMM clustering of x-vectors (VBx), called MS-VBx. Experiments on three datasets demonstrate that MS-VBx outperforms cAHC in diarization and speaker counting performance.Comment: Accepted at Interspeech 202

Efficacy and tolerance of the topical application of potassium hydroxide (10% and 15%) in the treatment of molluscum contagiosum: Randomized clinical trial: Research protocol

<p>Abstract</p> <p>Background</p> <p>Molluscum contagiosum is a non-severe pediatric viral infection. Because it is highly contagious and current treatments have negative aesthetic and psychological effects, we want to test an alternative treatment in the primary care setting, consisting of two different concentrations of potassium hydroxide solution.</p> <p>Methods/design</p> <p>The study design is a double-blind, randomized clinical trial, using three types of topical treatment. The treatment consist of daily applications of potassium hydroxide (KOH) in aqueous solution at 10% and 15% concentration, and a placebo administered in the control group. Four follow-up visits (at 15, 30, 45 and 60 days) are planned to evaluate treatment effectiveness and patient tolerance.</p> <p>The main outcome measure of the trial will be the healing rate, defined as lesion disappearance in the affected zones after the topic application of the experimental treatment. Secondary measures will be the principal characteristics and evolution of the affected zone (surface area, number of lesions, size and density of lesions), treatment tolerance (hyperpigmentation, itching, burning, pain), recurrence rate and the natural evolution of lesions in the control group.</p> <p>Discussion</p> <p>KOH can potentially be an effective and safe treatment for MC in primary care, and can also reduce referrals to dermatologists and hospital pediatric departments. In addition, KOH may be a valid and less expensive alternative to current invasive treatments (surgical excision).</p> <p>Trial Registration</p> <p>ClinicalTrials.gov: <a href="http://www.clinicaltrials.gov/ct2/show/NCT01348386">NCT01348386</a></p