2,188 research outputs found

    Rate- and State-Dependent Friction Law and Statistical Properties of Earthquakes

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    In order to clarify how the statistical properties of earthquakes depend on the constitutive law characterizing the stick-slip dynamics, we make an extensive numerical simulation of the one-dimensional spring-block model with the rate- and state-dependent friction law. Both the magnitude distribution and the recurrence-time distribution are studied with varying the constitutive parameters characterizing the model. While a continuous spectrum of seismic events from smaller to larger magnitudes is obtained, earthquakes described by this model turn out to possess pronounced ``characteristic'' features.Comment: Minor revisions are made in the text and in the figures. Accepted for publication in Europhys. Letter

    A Caenorhabditis motif compendium for studying transcriptional gene regulation

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    <p>Abstract</p> <p>Background</p> <p>Controlling gene expression is fundamental to biological complexity. The nematode <it>Caenorhabditis elegans </it>is an important model for studying principles of gene regulation in multi-cellular organisms. A comprehensive parts list of putative regulatory motifs was yet missing for this model system. In this study, we compile a set of putative regulatory motifs by combining evidence from conservation and expression data.</p> <p>Description</p> <p>We present an unbiased comparative approach to a regulatory motif compendium for <it>Caenorhabditis </it>species. This involves the assembly of a new nematode genome, whole genome alignments and assessment of conserved <it>k-</it>mers counts. Candidate motifs are selected from a set of 9,500 randomly picked genes by three different motif discovery strategies. Motif candidates have to pass a conservation enrichment filter. Motif degeneracy and length are optimized. Retained motif descriptions are evaluated by expression data using a non-parametric test, which assesses expression changes due to the presence/absence of individual motifs. Finally, we also provide condition-specific motif ensembles by conditional tree analysis.</p> <p>Conclusion</p> <p>The nematode genomes align surprisingly well despite high neutral substitution rates. Our pipeline delivers motif sets by three alternative strategies. Each set contains less than 400 motifs, which are significantly conserved and correlated with 214 out of 270 tested gene expression conditions. This motif compendium is an entry point to comprehensive studies on nematode gene regulation. The website: http://corg.eb.tuebingen.mpg.de/CMC has extensive query capabilities, supplements this article and supports the experimental list.</p

    Acoustic radiation controls friction: Evidence from a spring-block experiment

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    Brittle failures of materials and earthquakes generate acoustic/seismic waves which lead to radiation damping feedbacks that should be introduced in the dynamical equations of crack motion. We present direct experimental evidence of the importance of this feedback on the acoustic noise spectrum of well-controlled spring-block sliding experiments performed on a variety of smooth surfaces. The full noise spectrum is quantitatively explained by a simple noisy harmonic oscillator equation with a radiation damping force proportional to the derivative of the acceleration, added to a standard viscous term.Comment: 4 pages including 3 figures. Replaced with version accepted in PR

    Melt viscosities of lattice polymers using a Kramers potential treatment

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    Kramers relaxation times Ï„K\tau_{K} and relaxation times Ï„R\tau_{R} and Ï„G\tau_{G} for the end-to-end distances and for center of mass diffusion are calculated for dense systems of athermal lattice chains. Ï„K\tau_{K} is defined from the response of the radius of gyration to a Kramers potential which approximately describes the effect of a stationary shear flow. It is shown that within an intermediate range of chain lengths N the relaxation times Ï„R\tau_{R} and Ï„K\tau_{K} exhibit the same scaling with N, suggesting that N-dependent melt-viscosities for non-entangled chains can be obtained from the Kramers equilibrium concept.Comment: submitted to: Journal of Chemical Physic

    A relativistic Glauber approach to polarization transfer in 4He(\vec{e},e'\vec{p})

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    Polarization-transfer components for 4He(\vec{e},e'\vec{p})3H are computed within the relativistic multiple-scattering Glauber approximation (RMSGA). The RMSGA framework adopts relativistic single-particle wave functions and electron-nucleon couplings. The predictions with free and various parametrizations for the medium-modified electromagnetic form factors are compared to the world data.Comment: 2 pages, 1 figure Proceedings of the Int. School on Nuclear Physics, 26th Course, Erice (Sicily), September 16th- 24th, 2004; To appear in Progress in Particle and Nuclear Physic
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