115 research outputs found
Monitoring on-going vision development in system change programmes
Visions are considered to be of vital importance for programmes aimed at sustainable systems change. Vision development is a programme management instrument, a programme output, and at the heart of programme learning processes. This article addresses the question what constitutes an appropriate monitoring strategy for vision development activities within system change programmes. Based on action research and literature review on monitoring, evaluation and vision development a monitoring framework is proposed. It is suggested to monitor the programme vision against project visions, societal visions and a set of basic criteria. The monitoring activities themselves are context-sensitive and frequently renegotiated between monitors, programme managers and other stakeholders. The framework is illustrated with a national systems change programme on sustainable agriculture in the Netherlands. </jats:p
Systematic review on the comparative effectiveness of foot orthoses in patients with rheumatoid arthritis
BackgroundFoot orthoses (FOs) are prescribed as an important conservative treatment option in patients with foot problems related to rheumatoid arthritis. However, a broad variation in FOs is used, both in clinical practice and in research. To date, there is no overview on the outcomes of the treatment with different kinds of FOs in patients with rheumatoid arthritis and a specific foot problem. The objectives of the present study were to summarize the comparative effectiveness of FOs in the treatment of various foot problems in patients with rheumatoid arthritis, on the primary outcomes foot function and foot pain, and the secondary outcomes physical functioning, health related quality of life, compliance, adverse events, the costs of FOs and patient satisfaction.MethodsStudies comparing different kinds of FOs, with a presumed therapeutic effect, in the treatment of foot problems related to rheumatoid arthritis were included. A literature search was conducted in The Cochrane Central Registry for Controlled Trials (CENTRAL), PubMed, EMBASE and PEDro up to May 18th, 2018. Data was meta-analyzed, when this was not possible qualitative data analysis was performed.ResultsTen studies were identified, with a total number of 235 patients. These studies made a comparison between different materials used (soft versus semi-rigid), types of FOs (custom-made versus ready-made; total-contact versus non-total contact), or modifications applied (metatarsal bars versus domes). Also, different techniques to construct custom-made FOs were compared (standard custom-molding techniques versus more sophisticated techniques). A medium effect for (immediate) reduction of forefoot plantar pressure was found in favor of treatment with soft FOs compared to semi-rigid FOs (SMD 0.60, 95% CI 0.07-1.14; P=0.03; 28 participants). Other comparisons between FOs resulted in non-significant effects or inconclusive evidence for one kind of FOs over the other.ConclusionsFoot orthoses made of soft materials may lead to more (immediate) forefoot plantar pressure reduction compared to foot orthoses constructed of semi-rigid materials. Definitive high quality RCTs, with adequate sample sizes and long-term follow-up, are needed to investigate the comparative (cost-) effectiveness of different kinds of foot orthoses for the treatment of foot problems related to rheumatoid arthritis
Recommended from our members
Reāevaluation of propaneā1,2ādiol alginate (E 405) as a food additive
The present opinion deals with the reāevaluation of propaneā1,2ādiol alginate (E 405) when used as a food additive. The Panel noted that absorption, distribution, metabolism and excretion (ADME) data on propaneā1,2ādiol alginate gave evidence for the hydrolysis of this additive into propaneā1,2ādiol and alginic acid. These two compounds have been recently reāevaluated for their safety of use as food additives (EFSA ANS Panel, 2017, 2018). Consequently, the Panel considered in this opinion the major toxicokinetic and toxicological data of these two hydrolytic derivatives. No adverse effects were reported in subacute and subchronic dietary studies with propaneā1,2ādiol alginate. The available data did not indicate a genotoxic concern for propaneā1,2ādiol alginate (E 405) when used as a food additive. Propaneā1,2ādiol alginate, alginic acid and propaneā1,2ādiol were not of concern with respect to carcinogenicity. The Panel considered that any adverse effect of propaneā1,2ādiol alginate would be due to propaneā1,2ādiol. Therefore, the acceptable daily intake (ADI) of the food additive E 405 is determined by the amount of free propaneā1,2ādiol and the propaneā1,2ādiol released from the food additive after hydrolysis. According to the EU specification, the concentration of free and bound propaneā1,2ādiol amounts to a maximum of 45% on a weight basis. On the worstācase assumption that 100% of propaneā1,2ādiol would be systemically available and considering the ADI for propaneā1,2ādiol of 25 mg/kg body weight (bw) per day, the Panel allocated an ADI of 55 mg/kg bw per day for propaneā1,2ādiol alginate. The Panel concluded that exposure estimates did not exceed the ADI in any of the population groups from the use of propaneā1,2ādiol alginate (E 405) as a food additive. Therefore, the Panel concluded that there is no safety concern at the authorised use levels
The association between physical activity and neck and low back pain: a systematic review
The effect of physical activity on neck and low back pain is still controversial. No systematic review has been conducted on the association between daily physical activity and neck and low back pain. The objective of this study was to evaluate the association between physical activity and the incidence/prevalence of neck and low back pain. Publications were systematically searched from 1980 to June 2009 in several databases. The following key words were used: neck pain, back pain, physical activity, leisure time activity, daily activity, everyday activity, lifestyle activity, sedentary, and physical inactivity. A hand search of relevant journals was also carried out. Relevant studies were retrieved and assessed for methodological quality by two independent reviewers. The strength of the evidence was based on methodological quality and consistency of the results. Seventeen studies were included in this review, of which 13 were rated as high-quality studies. Of high-quality studies, there was limited evidence for no association between physical activity and neck pain in workers and strong evidence for no association in school children. Conflicting evidence was found for the association between physical activity and low back pain in both general population and school children. Literature with respect to the effect of physical activity on neck and low back pain was too heterogeneous and more research is needed before any final conclusion can be reached
- ā¦