3,561 research outputs found

    La glosa que escribió en latín Gregorio Lopez

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    Copia digital. Valladolid : Junta de Castilla y León. Consejería de Cultura y Turismo, 2009-2010Precede al tít.: Código de las siete PartidasVól. II y III: Imprenta de F. Maroto e Hijo

    PAMP-triggered immunity against Pseudomonas syringae involves microRNA-mediated regulation of several uncharacterized R genes

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    Two main types of noncoding small RNA molecules have been found in plants: microRNAs (miRNAs) and small interfering RNAs (siRNAs). They differ in their biogenesis and mode of action, but share similar sizes (20-24 nt). Their precursors are processed by Dicer-Like RNase III (dcl) proteins present in Arabidopsis thaliana, and in their mature form can act as negative regulators of gene expression, being involved in a vast array of plant processes, including plant development, genomic integrity or response to stress. Small-RNA mediated regulation can occurs at transcriptional level (TGS) or at post-transcriptional level (PTGS). In recent years, the role of gene silencing in the regulation of expression of genes related to plant defence responses against bacterial pathogens is becoming clearer. Comparisons carried out in our lab between the expression profiles of different mutants affected in gene silencing, and plants challenged with Pseudomonas syringae pathovar tomato DC3000, led us to identify a set of uncharacterized R genes, belonging to the TIR-NBS-LRR gene family, differentially expressed in these conditions. Through the use of bioinformatics tools, we found a miRNA* of 22 nt putatively responsible for down-regulating expression of these R genes through the generation of siRNAs. We have also found that the corresponding pri-miRNA is down-regulated after PAMP-perception in a SA-dependent manner. We also demonstrate that plants with altered levels of miRNA* (knockdown lines or overexpression lines) exhibit altered PTI-associated phenotypes, suggesting a role for this miRNA* in this defence response against bacteria. In addition we identify one of the target genes as a negative regulator of defence response against Pseudomonas syringae.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. MINECO, FEDE

    Radiative heat transfer in 2D Dirac materials

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    We compute the radiative heat transfer between two sheets of 2D Dirac materials, including topological Chern insulators and graphene, within the framework of the local approximation for the optical response of these materials. In this approximation, which neglects spatial dispersion, we derive both numerically and analytically the short-distance asymptotic of the near-field heat transfer in these systems, and show that it scales as the inverse of the distance between the two sheets. Finally, we discuss the limitations to the validity of this scaling law imposed by spatial dispersion in 2D Dirac materials.Comment: 15 pages, 4 figures. Updated version including corrected analysis of the far-field regim

    Adding Support for Automatic Enforcement of Security Policies in NFV Networks

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    This paper introduces an approach towards automatic enforcement of security policies in fv networks and dynamic adaptation to network changes. The approach relies on a refinement model that allows the dynamic transformation of high-level security requirements into configuration settings for the Network Security Functions (NSFs), and optimization models that allow the optimal selection of the NSFs to use. These models are built on a formalization of the NSF capabilities, which serves to unequivocally describe what NSFs are able to do for security policy enforcement purposes. The approach proposed is the first step towards a security policy aware NFV management, orchestration, and resource allocation system - a paradigm shift for the management of virtualized networks - and it requires minor changes to the current NFV architecture. We prove that our approach is feasible, as it has been implemented by extending the OpenMANO framework and validated on several network scenarios. Furthermore, we prove with performance tests that policy refinement scales well enough to support current and future virtualized networks

    Mixed matrix carbon stainless steel (MMCSS) hollow fibres for gas separation

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    This work reports the preparation and investigation of novel mixed matrix carbon stainless steel (MMCSS) membranes. The study involves the production of MMCSS hollow fibres using SS particles of 6, 10, 16 and 45\ua0μm in diameter, polyetherimide as a polymeric binder and pyrolysis using a N inert atmosphere. As a result, the binder pyrolysed to carbon was retained in the hollow fibre structure, filling the voids between the SS particles. Smaller SS particles (6\ua0μm) yielded a bi-modal pore size distribution and superior mechanical properties. An interesting morphological feature was the formation of honeycomb-like carbon structures between the SS particles, attributed to the densification of the hollow fibre during pyrolysis at 1050\ua0°C. The MMCSS hollow fibres (6\ua0μm) delivered almost pure N for the separation of a synthetic flue gas composition (13% CO and 87% N). It was found that CO had a strong affinity to the surface of the MMCSS materials (isosteric heat of adsorption of 38\ua0kJ\ua0mol) whilst N was a non-absorbing gas. Therefore, CO permeation was controlled by surface diffusion whilst N was controlled by the faster Knudsen diffusion mechanism. For CO feed concentrations in excess of 13%, the CO diffusion increased as the excess CO could not adsorb on the fully saturated surface of the MMCSS hollow fibres, thus slightly reducing the N purity in the permeate stream

    Análisis del solapamiento funcional entre la respuesta de la planta frente a efectores secretados por Pseudomonas syringae y el silenciamiento génico

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    Las plantas están continuamente sometidas a infecciones por diferentes patógenos. Los patógenos bacterianos usan un complejo sistema de secreción para translocar proteínas efectoras al interior del huésped y suprimir así las respuestas de defensas. En los últimos años, se ha demostrado la participación de ciertos microRNAs en respuestas de defensas de la planta frente a patógenos bacterianos, así como la actuación de erectores bacterianos en rutas reguladas por miRNAs. Sin embargo poco se sabe acerca de cómo la regulación por microRNAs afecta a las respuestas de defensas de la planta frente a patógenos bacterianos, y de hecho menos es conocido sobre el impacto de la supresión de defensas mediada por efectores sobre las rutas reguladas por microRNAs. En este estudio, hemos realizado comparaciones entre análisis de microarrays, con el objetivo de diferenciar genes expresados diferencialmente (DEGs) en Arabidopsis, comunes entre la respuesta de defensa frente a efectores de Pseudomonas syringae y mutantes afectados en la biogénesis de miRNAs. El análisis de la anotación funcional de los DEGS comunes identificados, seguidos de un análisis de expresión mediante RT-qPCR nos ha servido para identificar procesos biológicos regulados por rutas de miRNAs en la interacción planta-patógenoUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. Junta de Andalucía, Proyectos de Excelencia P06-CVI-02088; MINECO, Plan Nacional BIO2012-3564

    The Isolation Concept in the 5G Network Slicing

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    The fifth generation (5G) of cellular networks shall host a number of tenants and provide services tailored to meet a wide range of requirements in terms of performance, dependability and security. Network slicing will be a key enabler, by assigning dedicated resources and functionalities to meet such requirements, where the isolation between slices, i.e., that a slice may operate without interference from other slices, becomes a core issue. The objective of this paper is to give a thorough insight into the isolation concept, discuss the challenges involved in providing it, and outline the means available to provide various levels of isolation. Fundamental concepts that can be used in further work to build an isolation solution tailored to specific needs. This paper defines important concepts such as the Provider Management, the Tenant Management, and the Means of Isolation in the context of the Isolation Dimensions. The conclusion of the study is that dealing with isolation between slices needs extensions in state of the art on the mentioned concepts, and in how to tailor the isolation to meet the needs in a cost-efficiency manner.acceptedVersio
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