2,706 research outputs found

    What drives electric vehicle drivers' satisfaction and continuance intention?

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    Cruz-Jesus, F., Figueira-Alves, H., Tam, C., Pinto, D. C., Oliveira, T., & Venkatesh, V. (2023). Pragmatic and idealistic reasons: What drives electric vehicle drivers' satisfaction and continuance intention? Transportation Research Part A: Policy and Practice, 170(April), 1-16. [103626]. https://doi.org/10.1016/j.tra.2023.103626The sales and use of electric vehicles (EVs) have been growing in recent times in Europe, with the hopes of mitigating CO2 emissions and enabling more sustainable transportation. Considering the growth of the EV market, the main goal of this research is to shed light on what drives electric vehicles' satisfaction and continuance intention. We collected data from 290 EV drivers in Europe. Grounded in the task-technology fit model and expectation-confirmation theory, we explained 22 % and 40 % of the variance in EV satisfaction and continuance intention, with green self-identity as a moderator. EV satisfaction and continuance intention are primarily driven by adequate infrastructure and environmental concerns.publishersversionpublishe

    A IMPORTÂNCIA DO EPI NA CONSTRUÇÃO CIVIL

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    Resumo: Dentre os setores econômicos do país um dos que mais cresce é a construção civil. Com esse crescimento repentino o número de acidentes dentro dos canteiros de obras tem chegado a números surpreendentes. Para se combater essas estatísticas as empresas devem buscar métodos cada vez mais eficazes dentro da área de segurança do trabalho. O EPI (Equipamento de Proteção Individual), treinamentos constantes e os programas de segurança são as bases para diminuir o número de acidentes e mortes dentro da indústria da construção civil.     Palavras-chave: construção civil, acidente de trabalho, equipamento de proteção individual e prevenção

    TV digital, publicidade e audiência

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    This article aims to analyze the advertising segment and their relationship with the development process of the digital television. We intent to observe the new perspectives of production and consumption of media. Among other things, that involves the issues of interactivity, the exhaustion of the traditional media models, and the relationship of the new media with the audience, considering the analysis of the tripod: digital television, advertising and audience. In Brazil, with the implementation of the Brazilian System of Digital Television (SBTVD), the problem takes bigger proportions, as a consequence of the possibility to issue and track down the digital content consumed. That happens as a consequence of the consumer ability to watch the program with or without the commercial break. At the current model of television, the public is the legitimizing factor: the broadcasters issues the public attention as an instrument to obtain pecuniary rewarding of the advertisers. That model constitutes itself as the main funding source of the channels and networks. On the one hand, digital television represents an advantage at the quality of picture and audio, multiplying the capacity to transmit television signals and to transport new features and services.  On the other hand, it seems impossible to transform this industry without some reaction. The many interests involved constitute the main cause of that scenario: the agents interested in advertising are those concerned with the role of ideology, the support of capitalism and the industrial culture. Considering all these questions, it seems almost impossible to produce deep chances, contrary to the interests involved.A TV digital representa uma importante inovação, cujas vantagens variam, conforme as diversas modulações possíveis, e que podem ser resumidas na superior qualidade de imagem e áudio, multiplicação da capacidade de transmissão de sinais televisivos e transporte de novos serviços e recursos. Centrando a discussão em três abordagens - TV digital, audiência e publicidade - o presente artigo pretende analisar a abertura de novas possibilidades de comercialização na maior vitrine da publicidade, no que tende a ser uma transformação profunda na forma de abordar consumidores, e de planejar as ações de mídia. A própria possibilidade de interatividade, ao longo dos próximos anos, pode apresentar serviços que se tornarão parte do cotidiano dos telespectadores. Estes são temas cruciais num quadro de convergência, em que a radiodifusão e telecomunicação imbricam-se, ampliando ainda mais a oferta de produtos em uma mesma plataforma

    In vitro evaluation of alkaline lignins as antiparasitic agents and their use as an excipient in the release of benznidazole

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    Copyright © 2023. Published by Elsevier B.V.The Amazon rainforest is considered the largest tropical timber reserve in the world. The management of native forests in the Amazon is one of the most sensitive geopolitical issues today, given its national and international dimension. In this work, we obtained and characterized physicochemical lignins extracted from branches and leaves of Protium puncticulatum and Scleronema micranthum. In addition, we evaluated in vitro its potential as an antioxidant, cytotoxic agent against animal cells and antiparasitic against promastigotes of Leishmania amazonensis, trypomastigotes of T. cruzi and against Plasmodium falciparum parasites sensitive and resistant to chloroquine. The results showed that the lignins obtained are of the GSH type and have higher levels of guaiacyl units. However, they show structural differences as shown by spectroscopic analysis and radar charts. As for biological activities, they showed antioxidant potential and low cytotoxicity against animal cells. Antileishmanial/trypanocidal assays have shown that lignins can inhibit the growth of promastigotes and trypomastigotes in vitro. The lignins in this study showed low anti-Plasmodium falciparum activity against susceptible strains of Plasmodium falciparum and were able to inhibit the growth of the chloroquine-resistant strain. And were not able to inhibit the growth of Schistosoma mansoni parasites. Finally, lignins proved to be promising excipients in the release of benznidazole. These findings show the potential of these lignins not yet studied to promote different biological activities.publishersversionpublishe

    QUEDAS EM PACIENTES DA ATENÇÃO DOMICILIAR: PREVALÊNCIA E FATORES ASSOCIADOS

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    RESUMO Objetivo: estimar a prevalência de quedas, identificar os fatores associados e estabelecer modelo de predição para seu desenvolvimento em pacientes atendidos por um programa de atenção domiciliar. Métodos estudo transversal realizado entre junho de 2017 e janeiro de 2018, com 131 pacientes atendidos pelo Programa Melhor em Casa, de uma cidade do norte de Minas Gerais. Com o auxílio de um instrumento foram coletados dados sociodemográficos e clínicos. Realizou-se análise descritiva e as razões de prevalências ajustadas foram obtidas por análise múltipla de regressão de Poisson com variância robusta. Resultados: dos 131 pacientes, 72 (55%) eram do sexo feminino, a média de idade foi de 66,8 anos e 43,5% apresentaram queda. As variáveis independentes que impactaram de forma significativa e conjunta no desfecho queda foram: tipo de queda - acidental; local de queda - quarto; local de queda - sala; local de queda - cozinha; local de queda - quintal; local de queda - rua; e medo de novas quedas. Conclusão: a queda é achado comum em pacientes da atenção domiciliar e cuidados para sua prevenção devem ser estabelecidos

    Biological activities and physicochemical characterization of alkaline lignins obtained from branches and leaves of Buchenavia viridiflora with potential pharmaceutical and biomedical applications

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    Funding Information: The study was funded by Foundation for the State of Pernambuco (Process - FACE-04.03/19 ), AP Researcher Research Grant - FACEPE (Process BFP-0038-0 ) and National Council for Scientific and Technological Development grant - CNPq (Process 306865/2020-3 ). This research was also funded by the Foundation for Science and Technology (FCT) through the GHTM ( UID/04413/2020 ). Thanks to MR4, who provided us with the Plasmodium falciparum strains that we used in the assays. We also thank the Laboratory of Magnetic Resonance of the Institute of Chemistry and Biotechnology (Federal University of Alagoas- UFAL) for the analysis of NMR. In addition to these, we would also like to thank Mil Madeiras Preciosas, a subsidiary of the Swiss group Precious Woods ( http://preciouswoods.com.br/ ) for providing samples of branches and leaves of Buchenavia viridiflora. Publisher Copyright: © 2022In this work, we investigated in vitro different biological activities of alkaline lignins extracted from the species Buchenavia viridiflora, a tree from the Amazon rainforest used as a wood product. The chemical composition results for the twig and leaves were, respectively (%): cellulose (30.88 and 24. 28), hemicellulose (21.62 and 23.03), lignin (29.93 and 25.46), extractives (13.06 and 20.52), and ash (4.51 and 6.72). The yield was higher for the lignin of the branches (67.9 %) when compared to the leaves (60.2 %). Lignins are of the GSH type, low molecular weight and thermally stable. They promoted moderate to low antioxidant activity, highlighting the lignin of the branches, which presented an IC50 of 884.56 μg/mL for the DPPH assay and an IC50 of 14.08 μg/mL for ABTS. In the cytotoxicity assays, they showed low toxicity against macrophage cells (IC50 28.47 and 22.58 μg/mL). In addition, they were not cytotoxic against splenocytes and erythrocytes at concentrations ranging from 100 to 6.25 μg/mL. These were able to promote splenocyte proliferation and induce the production of anti-inflammatory cytokines. And inhibit the growth of tumor cells with IC50 ranging from 12.63 to values >100 μg/mL and microbial at a concentration of 512 μg/mL. Finally, they showed antiparasitic activity by inhibiting the growth of chloroquine-sensitive and resistant Plasmodium falciparum strains. These findings reinforce that the lignins in this study are promising for potential pharmaceutical and biomedical applications.publishersversionpublishe

    Synthesis, characterization, antioxidant and antiparasitic activities new naphthyl-thiazole derivatives

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    Copyright © 2023. Published by Elsevier Inc.In this work, 13 thiosemicarbazones (1a - m) and 16 thiazoles (2a - p) were obtained, which were properly characterized by spectroscopic and spectrometric techniques. The pharmacokinetic properties obtained in silico revealed that the derivatives are in accordance with the parameters established by lipinski and veber, showing that such compounds have good bioavailability or permeability when administered orally. In assays of antioxidant activity, thiosemicarbazones showed moderate to high antioxidant potential when compared to thiazoles. In addition, they were able to interact with albumin and DNA. Screening assays to assess the toxicity of compounds to mammalian cells revealed that thiosemicarbazones were less toxic when compared to thiazoles. In relation to in vitro antiparasitic activity, thiosemicarbazones and thiazoles showed cytotoxic potential against the parasites Leishmania amazonensis and Trypanosoma cruzi. Among the compounds, 1b, 1j and 2l stood out, showing inhibition potential for the amastigote forms of the two parasites. As for the in vitro antimalarial activity, thiosemicarbazones did not inhibit Plasmodium falciparum growth. In contrast, thiazoles promoted growth inhibition. This study shows in a preliminary way that the synthesized compounds have antiparasitic potential in vitro.publishersversionpublishe

    Métodos de aplicação de potássio na qualidade do milho verde em sucessão ao cultivo de melancia

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    Este trabalho foi realizado em área de savana (cerrado), recém incorporada ao sistema produtivo, localizada no Centro de Ciências Agrárias da UFRR, no município de Boa Vista, em Roraima. Objetivou-se avaliar o efeito de seis métodos de aplicação de potássio nas características da planta e na qualidade de espigas de milho verde cultivadas em covas novas e em covas remanescente do cultivo de melancia. Os métodos de aplicação do potássio foram: 1 - 100% do potássio aplicado no plantio com a adição de esterco bovino na cova; 2 - 100% de K no plantio; 3 - 50% de K no plantio e 50% aos 20 dias após a emergência (DAE); 4 - 50% de K no plantio, 25% aos 20 DAE e 25% aos 30 DAE; 5 - 25% de K no plantio, 25% aos 20 DAE, 25% aos 30 DAE e 25% aos 40 DAE; 6 - 25% de K no plantio, 25% aos 50 DAE, 25% aos 60 DAE e 25% aos 70 DAE. O delineamento experimental foi o de blocos casualizados, em parcela subdividida, com quatro repetições. Nas parcelas foram aleatorizados os métodos de aplicação de potássio e nas subparcelas foram os tipos de covas. Os métodos de aplicação de potássio influenciaram positivamente nas variáveis analisadas, sobretudo nas covas remanescentes da melancia (CM), destacando-se os métodos 1, 3 e 4. Os métodos 2 e 6 determinaram os piores desempenhos

    Optimization tifton-85 grass cutting for productivity and nutrient value

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    The objective of this work was to determine the impact of cutting Tifton-85 grass at 14, 28, 42, 46, 70, and 80 days of regrowth on its production and nutritional characteristics during the rainy season. The study area of 238 m2 was divided into four sub-area, with 6 plots of 2 × 2 m spaced 1 m between plots and 2 m between sub-area. Random block design was used. The statistical analyses were performed following a randomized block design. Results were obtained as means from evaluations conducted in two consecutive years. The neutral detergent fiber (NDF) and acid detergent fiber (ADF) increased as the cutting age increased. However, crude protein, NDF nitrogen, ADF nitrogen and leaves/stem relationship decreased as the cutting age increased. The production of digestible dry matter increased linearly as the cutting age increased. Similarly, grass height, green matter and dry matter production (DMP) increased as the cutting age increased. The different cutting age did not influence the nitrogen A, B1 + B2, and B3 fractions of the grass. However, the C fraction increased as the cutting age increased. Longer intervals between cuts increased the grass productivity per cut, but compromised its nutritional composition and leaves/stem relationship. For Tifton -85, the regrowth age of 28 days allows greater production of dry matter and greater accumulated production of crude protein and digestive dry matter in the rainy season or over time
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