The Maine Annex, vol. 2, no. 12

The Maine Annex announced the scheduled presentation by Margaret Chase Smith and reports the Brunswick campus would become co-educational

Open-front Systems

Dave Serfling and his family live in Preston, Minnesota, which is just north across the border from Decorah. Dave graduated from ISU in 1981 in farm operations. Serflings have a 50 sow farrow-to-finish operation and 80 cows they feed out. They also have sheep, and they own about 350 acres. They love Iowa so much, Dave\u27s wife even works in Iowa, so thanks for helping the economy. (laughter) Steve Williams and his wife live in Villisca, in Page County. Steve is a 1988 ISU business graduate. He has a total livestock operation with beef and a farrow-tofeeder pig operation. He feeds out a few. There are some interesting family ties and partnerships in Page County, and now his operation\u27s up to about 300 sows in a very productive and unique arrangement, which we\u27ll hear more about. Greg Vogel represents the ISU AG 450 Farm, which is located southwest of Ames , about a mile. This is actually a student-managed farm, and many of you are familiar with that concept that the students really manage it, for better or for worse. And they suffer all the advantages and perils of pure agriculture. Greg is the farm operator. He\u27s also an ISU grad (ag business, 1978) and finished a master\u27s in ag business in 1994. The farm is about 950 acres, and they have 200 sows out there. They run both outdoor and confmement operations. Last we\u27ll hear from my good friend, Dick Thompson. Dick and Sharon, of course, farm in Boone County. Dick and Sharon recently were recognized as the 1996 Farm Agricultural Leaders of The Year by the Des Moines Register, which was a tremendous honor for them. There farm is a little under 400 acres, they have been the driving force behind and the inspiration behind Practical Farmers of Iowa. Dick and Sharon have served as mentors for many, many farm families, not only in Iowa but nationwide. I know Dick and Sharon now have a cow-calf operation, and with their son, Rex, they have some of the facilities we\u27re talking about today, and they\u27re trying some new things in agriculture, so we\u27re pleased to have Dick here

Your career : a place for you in agriculture

Cover title."This series, first printed in the Missouri Ruralist, is reprinted here ... "--P. 2

Increasing Success with Online Degree Courses and Programs in the VCCS

Over the last three years, 724,116 online courses were attempted within the Virginia Community College System (VCCS). From these attempts, 206,533 resulted in a grade of D or F or a withdrawal, accounting for 29% of all attempted online courses (Virginia Community College System, 2015). This does not account for the students who may have dropped the course early in the semester to avoid academic and/or financial consequences. Studies have shown that students who do not experience success in their courses drop out significantly more than their counterparts (Thayer, 1973). Additionally, these students experience delayed degree or certificate completions, higher program costs and student debt. It is for these reasons, that we must explore ways to increase student success in online courses and programs. By addressing accessibility to and student readiness for online education as well as applying best practices for distance learning, the VCCS can positively impact student success with online degree courses and programs

Superconducting Quantum Interference Device based on MgB2 nanobridges

The recently discovered superconductor MgB2, with a transition temperature of 39K, has significant potential for future electronics. An essential step is the achievement of Josephson circuits, of which the superconducting quantum interference device (SQUID) is the most important. Here, we report Josephson quantum interference in superconducting MgB2 thin films. Modulation voltages of up to 30 microvolt are observed in an all-MgB2 SQUID, based on focused ion beam patterned nanobridges. These bridges, with a length scale < 100 nm, have outstanding critical current densities of 7 x 10^6 A/cm2 at 4.2 K.Comment: submitted to Appl. Phys. Let

The road to magnesium-diboride thin films, Josephson junctions and SQUIDs

The remarkably high critical temperature at which magnesium diboride (MgB2) undergoes transition to the superconducting state, Tc approx 40 K, has aroused great interest and has encouraged many groups to explore the properties and application potential of this novel superconductor. For many electronic applications and further basic studies, the availability of superconducting thin films is of great importance. Several groups have succeeded in fabricating superconducting MgB2 films. An overview of the deposition techniques for MgB2 thin film growth will be given, with a special focus on the in situ two-step process

Ariel - Volume 8 Number 2

Executive Editor James W. Lockard , Jr. Issue Editor Doug Hiller Business Manager Neeraj K. Kanwal University News Richard J. Perry World News Doug Hiller Opinions Elizabeth A. McGuire Features Patrick P. Sokas Sports Desk Shahab S. Minassian Managing Editor Edward H. Jasper Managing Associate Brenda Peterson Photography Editor Robert D. Lehman, Jr. Graphics Christine M. Kuhnl

Portfolio Vol. II N 4

Browne, Phil. Alumni . Picture. 2. Martindale, Virginia. A Statue By Jude . Prose. 3. Maxwell, Robert. Reflections . Poem. 6. Lewis, Lucy. Quiet Zone . Prose. 7. Varney, Chester. Tinder Box . Prose. 9. Beckham, Adela. Spring Harvest . Poem. 10. Beckham, Adela. Morning . Poem. 10. Black, James. The Drama at Denison . Prose. 11. Mackie, Reino. Landscape . Picture. 6. Flory, Doris. April Showers . Poem. 14. Flory, Doris. Aspiration . Poem. 14. Wager, Dick. Solitude . Poem. 14. Wager, Dick. Regret . Poem. 14. Bastida, Sorella y. Children on the Beach . Picture. 14. Saunders, Paul. Review of New Books . Prose. 15. Smith, Bob. Review of New Recordings . Prose. 15. Mitchell, Dave. A Farmyard . Picture. 16. Bonnet, Elsie. Hidden Village . Picture. 16. Taylor, Dave. Concerning Art . Prose. 17. Browne, Phil. Master Craftsman . Picture. 18. Deeds, Ed. Brothers, Sing On . Prose. 19. Boyd, Kate Olive. Spring at Denison . Poem. 20. Barss, William. Landscape . Picture. 20. Deane, Dorothy. The Taming of the Shrew . Prose. 21

The Bromodomain and Extra-Terminal Protein Inhibitor OTX015 Suppresses T Helper Cell Proliferation and Differentiation

BACKGROUND: Dynamic epigenetic alterations accompanying CD4+ T helper cell differentiation have been implicated in multiple autoimmune diseases. The bromodomain and extra-terminal (BET) proteins are epigenetic regulators that recognize and bind to acetylated histones in chromatin and are targets for pharmacological inhibition. In this study we tested a new BET inhibitor under clinical development, OTX015, to interrogate its effects on key CD4+ T cell subsets associated with autoimmunity. METHODS: Naïve and memory murine and human CD4+ T cells were isolated and differentiated into populations characterized by the expression of interferon (IFN)-γ and interleukin (IL)-17. Cultured cells were then exposed to varying concentrations of OTX015 in vitro, and its impact on cytokine expression was quantified by flow cytometry. In parallel, the expression of the transcription factors TBX21 and RORC was quantified by PCR. A previously studied BET inhibitor JQ1 was used as a pharmacological control. RESULTS: OTX015 suppressed both murine and human CD4+ T cell proliferation. Its impact on cytokine expression varied in murine and human naïve and memory subsets. OTX015 was similarly effective as JQ1 in the suppression of cytokines and T helper cell proliferation. Higher concentrations of OTX015 also had a greater impact on the viability of murine versus human cells. IL-17 and IFN-γ expression was not altered in murine memory CD4+ T cells, whereas in human memory CD4+ T cells, OTX015 inhibited IL-17, but not IFN-γ. Across all human T cell subsets OTX015 suppressed IL-17 more effectively than IFN-γ. CONCLUSION: Our studies demonstrate that OTX015 has anti-inflammatory effects by suppressing murine and human CD4+ T cell proliferation and subset-dependent proinflammatory cytokine expression, including the selective suppression of IL-17 in human memory CD4+ T cells

The Ursinus Weekly, October 26, 1953

British foreign policy is subject of Forum speaker • China collection now on display in Library • Trinity Church holds special student class • Sororities schedule rush week parties • PAC to sponsor bus trip to United Nations, Nov. 14 • Baby sitters made available to faculty for school events • Retreat yields extensive plans for Y activity • Junior class to hold dance November 7 • 1953 alumni news • Freshmen elect officers; Hummel named president • All my sons to be directed by Abramson • Cub and Key plans reunion • Alumnus receives appointment at Washington University • Tonsorial quartets to present program • Editorials: Do we want culture? • From scenery to sex • Engagements • Campus sororities open week of rushing activity • Quartet performs with spirit and versatility • Meistersingers schedule includes concerts, tour • Third team wins, tops Bryn Mawr, 4-0 • Belles tie E. Stroudsburg, Merrifield, Heller counter • Ursinus defeats Swarthmore, 38-21 • Bakermen win 3rd game; Lose fourth to Rutgers • JVs triumph, 6-1, defeating Albright • All-college hockey starts Saturdayhttps://digitalcommons.ursinus.edu/weekly/1480/thumbnail.jp