Creación, gestión y uso de objetos de aprendizaje en la Web

El proyecto “Creación, Gestión y Uso de objetos de Aprendizaje en un Entorno Web” se ha desarrollado en la asignatura Sistemas Informáticos. Tiene como objetivo la puesta en producción de la versión 1.0 del Museo Virtual García Santesmases de la Facultad de Informática de la Universidad Complutense de Madrid. Este proyecto se centra en la construcción de una herramienta que sirva para la creación y gestión de recursos educativos, Objetos de Aprendizaje, modulares que puedan ser utilizados por diversos sistemas de enseñanza. Los Objetos de Aprendizaje creados con la herramienta a la que se refiere este proyecto están basados en los objetos del museo de informática García Santesmases, por lo que también se pueden utilizar como elementos de un museo virtual. [ABSTRACT] The proyect called “Creation, Management and Use of Learning Objects in the Web” has been developed into the subject “Sistemas Informáticos”. The main target is the setting in production of the 1.0 version of the “Virtual García Santesmases Museum” located at the School of Computer Science of the Complutense University of Madrid. This project focuses in the construction of a tool to be useful in the creation and management of educational resources, Learning Objects, modular Objects that they may be used by various tuitional systems. The Learning Objects created with the tool that this project refers to itself are based in the objects of García Santesmases Museum, so that also they can utilize themselves like elements of a virtual museum

Estratigrafía de los depósitos arcósicos en el sector occidental de la Cuenca de Madrid

The western part of the Madrid Basin shows widespread arkosic deposits of Neogene age characterized by a massive appearance. On the basis of detailed geological mapping, five main stratigraphic units, ranging the Lower and Middle Miocene, have been distinguished in the area. These units can be correlated with the major Neogene units defined in the Madrid Basin. The stratigraphic correlation has been favoured by recent findings of mammal localities in the area

High-frequency stratigraphic architecture of a 3rd order depositional sequence in the coastal margin setting of Iberian Basin (Segovia Province, Spain)

En este trabajo se analiza la arquitectura estratigráfica detallada y la ciclicidad interna de la secuencia deposicional de 3er orden del Turoniense Superior – Coniaciense Basal en el margen costero de la Cuenca Ibérica (Provincia de Segovia), dentro de sucesiones predominantemente terrígenas con algunas intercalaciones carbonatadas de plataforma somera. La correlación de 16 columnas estratigráficas a lo largo de un perfil perpendicular al margen costero ha permitido identificar cuatro conjuntos de parasecuencias (4º orden) y 10 parasecuencias (5º orden), cuyo espesor y continuidad lateral varían en función de relaciones de onlap y toplap de las parasecuencias inferiores y superiores respectivamente, dentro de cada conjunto mayor (4º orden). Asimismo, dentro de las parasecuencias de 5º orden, se han identificado hasta dos parasecuencias de orden mayor (6º orden), cuyo reconocimiento está supeditado a los términos carbonatados de las sucesiones sedimentarias. En el trabajo se analiza la compleja superposición de cortejos sedimentarios que genera un patrón de apilamiento deposicional en el que coexisten tres rangos de secuencias de alta frecuencia (4º, 5º y 6º orden), aclarando las relaciones entre las facies terrígenas y carbonatadas en este margen costero, así como las diferentes tendencias sedimentarias que se reconstruyen en función de la escala de observación.The cyclicity and the stratigraphic architecture of the Upper Turonian-Lower Coniacian 3rd-order sequence have been analysed in the coastal margin of the Iberian Basin (north of the Central System, province of Segovia). This sequence is composed of coastal terrigenous sediments with some shallow shelf carbonate intercalations. The 3rd-order sequence is composed of several ranges of high-frequency superimposed parasequences. Each of the four parasequence sets (4th-order), can be divided into up to three parasequences (5th-order), which in turn are composed of two minor parasequences (6th-order), recognized only in the carbonate sediments of the sedimentary succession. Thickness and lateral extent of the parasequence sets depend on the number of their internal parasequences. Parasequences and minor parasequences thins and pinch out landwards with onlap and toplap relationships regarding the basal and top parasequence set and parasequence boundaries. The presence in the sedimentary record of 4th- 5th- and 6th-order parasequences originates a complex overlap of Systems Tracts; and thus, depending on the observation scale, different sedimentary trends can be recognized. At a detailed scale, the presence of these Systems Tracts allows to clarify the terrigenous and carbonate facies relationships. Although both facies have been formed in a single depositional episode, they were deposited in different stages of the episode. Siliciclastic facies represent the Shelf Margin Wedge/Transgressive Systems Tracts, being supplied to the Basin during a relative sea level lowstand and located at the coastal margin; later, during the subsequent transgression, they are reworked. On the other hand, carbonate sediments were deposited basinwards, during relative sea level highstands (Highstand System Tract). This depositional model explains the scarce presence of mixed facies. Two other different sedimentary trends are recognized in the entire sequence. First, the thinning upwards trend of parasequence sets, which is related with the overall regressive trend in the upper part of the sequence (due to accommodation loss). Secondly, the progressive upwards decrease of siliciclastic deposits and a correlative increase in carbonate sediments in the parasequence sets, which suggests the existence of a longer transgressive trend (2nd-order), which continues in the overlying Coniacian sequence.Depto. de Geodinámica, Estratigrafía y PaleontologíaFac. de Ciencias GeológicasTRUEMadrid (Comunidad Autónoma)Universidad de Alcalá de Henarespu

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

The Science Performance of JWST as Characterized in Commissioning

This paper characterizes the actual science performance of the James Webb Space Telescope (JWST), as determined from the six month commissioning period. We summarize the performance of the spacecraft, telescope, science instruments, and ground system, with an emphasis on differences from pre-launch expectations. Commissioning has made clear that JWST is fully capable of achieving the discoveries for which it was built. Moreover, almost across the board, the science performance of JWST is better than expected; in most cases, JWST will go deeper faster than expected. The telescope and instrument suite have demonstrated the sensitivity, stability, image quality, and spectral range that are necessary to transform our understanding of the cosmos through observations spanning from near-earth asteroids to the most distant galaxies.Comment: 5th version as accepted to PASP; 31 pages, 18 figures; https://iopscience.iop.org/article/10.1088/1538-3873/acb29

The James Webb Space Telescope Mission

Twenty-six years ago a small committee report, building on earlier studies, expounded a compelling and poetic vision for the future of astronomy, calling for an infrared-optimized space telescope with an aperture of at least $4m$. With the support of their governments in the US, Europe, and Canada, 20,000 people realized that vision as the $6.5m$ James Webb Space Telescope. A generation of astronomers will celebrate their accomplishments for the life of the mission, potentially as long as 20 years, and beyond. This report and the scientific discoveries that follow are extended thank-you notes to the 20,000 team members. The telescope is working perfectly, with much better image quality than expected. In this and accompanying papers, we give a brief history, describe the observatory, outline its objectives and current observing program, and discuss the inventions and people who made it possible. We cite detailed reports on the design and the measured performance on orbit.Comment: Accepted by PASP for the special issue on The James Webb Space Telescope Overview, 29 pages, 4 figure

Fundamentos para el cálculo - MA384 201801

Descripción: El curso de Fundamentos para el Cálculo es un curso teórico - práctico, dictado en modalidad Blended, dirigido a los estudiantes de Administración del primer ciclo y que trabaja en las primeras unidades los temas de ecuaciones, inecuaciones y gráficas en el plano, para poder acometer el estudio de las funciones en la unidad 3, y usarlas para resolver problemas de aplicación con contexto real. Las clases se imparten en 3 sesiones semanales, las dos primeras son presenciales y la tercera es online. Propósito: El curso está diseñado para desarrollar en los estudiantes la competencia de Razonamiento Cuantitativo, a nivel 1, por medio del estudio de situaciones problemáticas a las que, de ahora en adelante nos referiremos como casos, cuyo dominio les ayudará a desenvolverse con éxito en situaciones que involucran el pensamiento matemático para la toma de decisiones