IC 057 Gude to Diagnostic Clinic of Houston Records, 1985-1986

The Diagnostic Clinic of Houston records contains the newsletter, The Diagnosis from 1985 and 1986. The Diagnostic Clinic of Houston was established in 1957 when the nine founding members joined together to form a group practice. This organization was conceived in an attempt to provide the patients with the highest quality health care. See more at https://archives.library.tmc.edu/ic-057

Africa's Infrastructure: a time for transformation

Summary of Main FindingsAfrica's growth performance has improved markedly during the last decade. Ten out of 48 countries experienced sustained economic growth in excess of 5 percent for the past three years or longer. But that performance still falls short of the 7 percent growth needed to achieve substantial poverty reduction and attain the Millennium Development Goals. Infrastructure has played a significant role in Africa's recent economic turnaround and will need to play an even greater role if the continent's development targets are to be reached

A CPH-Like Picture in Two Patients with an Orbitocavernous Sinus Syndrome

Two patients with retroorbital pain syndromes with or without paresis of cranial nerves developed weeks after ipsilateral headache resembling chronic paroxysmal hemicrania (CPH) but without autonomic features. These findings might support the hypothesis that CPH may be caused by a pathological process in the region of the cavernous sinus, as has been proposed for the Tolosa-Hunt syndrome (THS)

South Dakota Animal Disease Research and Diagnostic Laboratory: Annual Report 2007

This document is the 2007 annual report of the South Dakota Veterinary and Biomedical Science Department Animal Disease Research and Diagnostic Laboratory

South Dakota Animal Disease Research & Diagnostic Laboratory User\u27s Guide

The ADRDL is an accredited AAVLD laboratory and a member of the USDA National Animal Health Network. This document is user\u27s guide for the services provided by the Animal Disease Research and Diagnostic Laboratory

South Dakota Animal Disease Research & Diagnostic Laboratory: Annual Report 2014

This document is the 2014 annual report of the South Dakota Veterinary and Biomedical Science Department Animal Disease Research and Diagnostic Laboratory

Calibration : the Achilles heel of predictive analytics

Acknowledgements This work was developed as part of the international STRengthening Analytical Thinking for Observational Studies (STRATOS) initiative. The objective of STRATOS is to provide accessible and accurate guidance in the design and analysis of observational studies (http://stratos-initiative.org/). Members of the STRATOS Topic Group ‘Evaluating diagnostic tests and prediction models’ are (alphabetically) Patrick Bossuyt, Gary S. Collins, Petra Macaskill, David J. McLernon, Karel G.M. Moons, Ewout W. Steyerberg, Ben Van Calster, Maarten van Smeden, and Andrew Vickers. Funding This work was funded by the Research Foundation – Flanders (FWO; grant G0B4716N) and Internal Funds KU Leuven (grant C24/15/037). The funders had no role in study design, data collection, data analysis, interpretation of results, or writing of the manuscript. Contributions All authors conceived of the study. BVC drafted the manuscript. All authors reviewed and edited the manuscript and approved the final version.Peer reviewedPublisher PD

Diagnostic standards and classification of tuberculosis in adults and children

A joint statement of the American Thoracic Society and the CDC, this article provides a framework for and an understanding of the diagnostic approaches to tuberculosis (TB) infection/disease and to present a classification scheme that facilitates management of all persons to whom diagnostic tests have been applied. The specific objectives of this revision of the Diagnostic Standards are to define diagnostic strategies for high- and low-risk patient populations based on current knowledge of TB epidemiology and information on newer technology and to provide a classification scheme for TB that is based on pathogenesis. Definitions of TB disease and latent infection have been selected that (1) aid in an accurate diagnosis; (2) coincide with the appropriate response of the health care team, whether it be no response, treatment of latent infection, or treatment of disease; (3) provide the most useful information that correlates with the prognosis; (4) provide the necessary information of appropriate public health action; and (5) provide a uniform, functional, and practical means of reporting. Because TB, even after it has been treated adequately, remains a pertinent and lifelong part of a person's medical history, previous as well as current disease is included in the classification. This edition of the Diagnostic Standards has been prepared as a practical guide and statement of principles for all persons involved in the care of patients with TB. References have been included to guide the reader to texts and journal articles for more detailed information on each topic. Section headings are (I) Epidemiology, (II) Transmission of Mycobacterium Tuberculosis, (III) Pathogenesis of Tuberculosis, (IV) Clinical Manifestations of Tuberculosis, (V) Diagnostic Microbiology, (VI) Tuberculin Skin Test, (VII) Classification of Persons Exposed to and/or Infected with Mycobacterium Tuberculosis, and (VIII) Reporting of Tuberculosis.I. Epidemiology -- II. Transmission of Mycobacterium Tuberculosis -- III. Pathogenesis of Tuberculosis -- IV. Clinical Manifestations of Tuberculosis -- V. Diagnostic Microbiology -- VI. Tuberculin Skin Test -- VII. Classification of Persons Exposed to and/or Infected with Mycobacterium Tuberculosis -- VIII. Reporting of Tuberculosis.This official statement of the American Thoracic Society and the Centers for Disease Control and Prevention was adopted by the ATS Board of Directors, July 1999. This statement was endorsed by the Council of the Infectious Disease Society of America, September 1999.Reprinted from American journal of respiratory and critical care medicine, Vol. 161, 2000.Also available on the World Wide Web (accessed 06/18/2010),Includes bibliographic references (p. 1392-1395)

Epidemiologic and Clinical Characteristics of Optic Neuritis in Japan

Purpose:To elucidate the clinical and epidemiologic characteristics of optic neuritis in Japan.Design:Multicenter cross-sectional, observational cohort study.Participants:A total of 531 cases of unilateral or bilateral noninfectious optic neuritis identified in 33 institutions nationwide in Japan.Methods:Serum samples from patients with optic neuritis were tested for anti–aquaporin-4 antibodies (AQP4-Abs) and anti–myelin oligodendrocyte glycoprotein antibodies (MOG-Abs) using a cell-based assay and were correlated with the clinical findings.Main Outcome Measures:Antibody positivity, clinical and radiologic characteristics, and visual outcome.Results:Among 531 cases of optic neuritis, 12% were AQP4-Ab positive, 10% were MOG-Ab positive, 77% were negative for both antibodies (double-negative), and 1 case was positive for both antibodies. Pretreatment visual acuity (VA) worsened to more than a median 1.0 logarithm of the minimum angle of resolution (logMAR) in all groups. After steroid pulse therapy (combined with plasmapheresis in 32% of patients in AQP4-Ab–positive group), median VA improved to 0.4 logMAR in the AQP4-Ab–positive group, 0 logMAR in the MOG-Ab–positive group, and 0.1 logMAR in the double-negative group. The AQP4-Ab–positive group showed a high proportion of females, exhibited diverse visual field abnormalities, and demonstrated concurrent spinal cord lesions on magnetic resonance imaging (MRI) in 22% of the patients. In the MOG-Ab–positive group, although posttreatment visual outcome was good, the rates of optic disc swelling and pain with eye movement were significantly higher than those in the AQP4-Ab–positive and double-negative groups. However, most cases showed isolated optic neuritis lesions on MRI. In the double-negative group, 4% of the patients had multiple sclerosis. Multivariate logistic regression analysis of all participants identified age and presence of antibodies (MOG-Ab and AQP4-Ab) as significant factors affecting visual outcome.Conclusions:The present large-scale cohort study revealed the clinicoepidemiologic features of noninfectious optic neuritis in Japan. Anti–aquaporin-4 antibody–positive optic neuritis has poor visual outcome. In contrast, MOG-Ab positive cases manifested severe clinical findings of optic neuritis before treatment, but few showed concurrent lesions in sites other than the optic nerve and generally showed good treatment response with favorable visual outcome. These findings indicate that autoantibody measurement is useful for prompt diagnosis and proper management of optic neuritis that tends to become refractory