The primary cancer morphology of fallopian tube

Introduction. Despite significant progress in the study of malignant tumors, the primary cancer of the fallopian tubes (PCFT) is not fully studied yet. According to different authors its incidence accounts from 0.14% to 1.8% of all female genital malignancies. The modern oncomorphology is in search of the criteria that will allow to verify the degree of biological malignancy and to predict the course of the disease with maximum objectivity. The study of molecular markers will allow to provide the adequate treatment of the patients with advanced processes and to improve the assessment of vulnerability to certain therapies

The primary cancer morphology of fallopian tube

Introduction. Despite significant progress in the study of malignant tumors, the primary cancer of the fallopian tubes (PCFT) is not fully studied yet. According to different authors its incidence accounts from 0.14% to 1.8% of all female genital malignancies. The modern oncomorphology is in search of the criteria that will allow to verify the degree of biological malignancy and to predict the course of the disease with maximum objectivity. The study of molecular markers will allow to provide the adequate treatment of the patients with advanced processes and to improve the assessment of vulnerability to certain therapies

СТРУКТУРООБРАЗОВАНИЕ СПЛАВОВ НА ЖЕЛЕЗНОЙ ОСНОВЕ ПОСЛЕ ЛАЗЕРНОГО ЛЕГИРОВАНИЯ

The paper is devoted to investigations on influence of laser treatment regimes of gas-thermal and adhesive coatings from self-fluxing powders on iron basis and after melting with modifying plaster on their roughness and phase composition. One of mathematical planning methods that is a complete factor experiment method has been used for investigation of parameters’ influence on micro-geometry of coatings. The executed investigations have made it possible to observe a general regularity which does not depend on a type of alloying plaster: while increasing speed of laser beam relatively to treated part, beam diameter value of Ra parameter is becoming less. Decrease in height of surface irregularities in case of increasing laser beam speed is related with intensification of evaporation processes. An increase in beam diameter diminishes Ra parameter of the surface. This is due to the fact that decrease in power density occurs at high rate of beam defocusing. Overlapping coefficient does not exert a pronounced effect on Ra parameter of fused coatings. While increasing the speed of laser beam relatively to the part structure is transferred from dendrite into supersaturated one with carbide and boride precipitations. It has been established that technological parameters of laser treatment and particularly speed of laser beam influence on coating composition. While increasing the speed up to v5 = 5 × 10–3 m/s amount of chromium has become larger by 1.5-fold that resulted in increase of micro-hardness of the coating from 9.5–10.1 GPa up to 11.04–15.50 GPa.Статья посвящена изучению влияния режимов лазерной обработки газотермических и клеевых покрытий из самофлюсующихся порошков на железной основе после оплавления с модифицирующими обмазками на их шероховатость и фазовый состав. Для исследования влияния параметров на микрогеометрию покрытий использован один из методов математического планирования – метод полного факторного эксперимента. В результате проведенных исследований прослежена общая закономерность, не зависящая от вида легирующей обмазки: с увеличением скорости луча лазера относительно обрабатываемой детали, диаметра луча значение параметра Ra становится меньше. Уменьшение высоты неровностей поверхности с ростом скорости луча лазера связано с интенсификацией процессов испарения. Увеличение диаметра луча уменьшает параметр Ra поверхности. Это связано с уменьшением плотности мощности при большей степени расфокусирования луча. Коэффициент перекрытия не оказывает заметного влияния на параметр Ra оплавляемых покрытий. С увеличением скорости движения луча лазера относительно детали структура из дендритной превращается в пересыщенную с выделениями карбидов и боридов. Установлено, что технологические параметры лазерной обработки, в частности скорость луча лазера, влияют на состав покрытий. С увеличением скорости до v5 = 5 × 10–3 м/с количество хрома стало больше в 1,5 раза, что привело к повышению микротвердости покрытия от 9,5–10,1 до 11,04–15,50 ГПа

ВСКРЫТИЕ МЕДЕПЛАВИЛЬНЫХ ШЛАКОВ ХЛОРИДОМ АММОНИЯ

A hydrometallurgical method of copper-smelting slag processing by means of ammonium chloride is proposed.  A basic processing diagram has been developed. Investigations of slag decomposition by ammonium chloride are conducted and the recommendations concerning the process implementation are given. Minerals, which form copper-smelting slag, are Fe2SiO4, Zn2SiO4, CuFe2O4 and Ca2SiO4. The decomposition should be carried out at temperature of 280 °C for 4 hours with continuous agitation and at slag/ammonium chloride ratio of 1 : 2.Предложен гидрометаллургический метод переработки медеплавильных шлаков с помощью хлорида аммония. Разработана принципиальная технологическая схема передела. Проведены исследования вскрытия шлака с помощью хлорида аммония и даны рекомендации по аппаратурному оформлению процесса. Минералами, образующими медеплавильный шлак, являются Fe2SiO4, Zn2SiO4, CuFe2O4 и Ca2SiO4. Вскрытие необходимо проводить при температуре 280 °С в течение 4 ч при постоянном перемешивании и соотношении шлак : хлорид аммония = 1 : 2

First results from the JWST Early Release Science Program Q3D: Benchmark Comparison of Optical and Mid-IR Tracers of a Dusty, Ionized Red Quasar Wind at z=0.435

The [OIII] 5007 A emission line is the most common tracer of warm, ionized outflows in active galactic nuclei across cosmic time. JWST newly allows us to use mid-infrared spectral features at both high spatial and spectral resolution to probe these same winds. Here we present a comparison of ground-based, seeing-limited [OIII] and space-based, diffraction-limited [SIV] 10.51 micron maps of the powerful, kpc-scale outflow in the Type 1 red quasar SDSS J110648.32+480712.3. The JWST data are from the Mid-InfraRed Instrument (MIRI). There is a close match in resolution between the datasets (0."4--0."6), in ionization potential of the O+2 and S+3 ions (35 eV), and in line sensitivity (1e-17 to 2e-17 erg/s/cm2/arcsec2). The [OIII] and [SIV] line shapes match in velocity and linewidth over much of the 20 kpc outflowing nebula, and [SIV] is the brightest line in the rest-frame 3.5--19.5 micron range, demonstrating its usefulness as a mid-IR probe of quasar outflows. [OIII] is nevertheless intriniscally brighter and provides better contrast with the point-source continuum, which is strong in the mid-IR. There is a strong anticorrelation of [OIII]/[SIV] with average velocity, which is consistent with a scenario of differential obscuration between the approaching (blueshifted) and receding (redshifted) sides of the flow. The dust in the wind may also obscure the central quasar, consistent with models that attribute red quasar extinction to dusty winds.Comment: Submitted to ApJ

First results from the JWST Early Release Science Program Q3D: Ionization cone, clumpy star formation and shocks in a z=3z=3 extremely red quasar host

Massive galaxies formed most actively at redshifts $z=1-3$ during the period known as `cosmic noon.' Here we present an emission-line study of an extremely red quasar SDSSJ165202.64+172852.3 host galaxy at $z=2.94$, based on observations with the Near Infrared Spectrograph (NIRSpec) integral field unit (IFU) on board JWST. We use standard emission-line diagnostic ratios to map the sources of gas ionization across the host and a swarm of companion galaxies. The quasar dominates the photoionization, but we also discover shock-excited regions orthogonal to the ionization cone and the quasar-driven outflow. These shocks could be merger-induced or -- more likely, given the presence of a powerful galactic-scale quasar outflow -- these are signatures of wide-angle outflows that can reach parts of the galaxy that are not directly illuminated by the quasar. Finally, the kinematically narrow emission associated with the host galaxy presents as a collection of 1 kpc-scale clumps forming stars at a rate of at least 200 $M_{\odot}$ yr$^{-1}$. The ISM within these clumps shows high electron densities, reaching up to 3,000 cm$^{-3}$ with metallicities ranging from half to a third solar with a positive metallicity gradient and V band extinctions up to 3 magnitudes. The star formation conditions are far more extreme in these regions than in local star-forming galaxies but consistent with that of massive galaxies at cosmic noon. JWST observations reveal an archetypical rapidly forming massive galaxy undergoing a merger, a clumpy starburst, an episode of obscured near-Eddington quasar activity, and an extremely powerful quasar outflow simultaneously.Comment: 19 pages, 8 figures. Accepted for publication in Ap

First results from the JWST Early Release Science Program Q3D: The Warm Ionized Gas Outflow in z ~ 1.6 Quasar XID 2028 and its Impact on the Host Galaxy

Quasar feedback may regulate the growth of supermassive black holes, quench coeval star formation, and impact galaxy morphology and the circumgalactic medium. However, direct evidence for quasar feedback in action at the epoch of peak black hole accretion at z ~ 2 remains elusive. A good case in point is the z = 1.6 quasar WISEA J100211.29+013706.7 (XID 2028) where past analyses of the same ground-based data have come to different conclusions. Here we revisit this object with the integral field unit of the Near Infrared Spectrograph (NIRSpec) on board the James Webb Space Telescope (JWST) as part of Early Release Science program Q3D. The excellent angular resolution and sensitivity of the JWST data reveal new morphological and kinematic sub-structures in the outflowing gas plume. An analysis of the emission line ratios indicates that photoionization by the central quasar dominates the ionization state of the gas with no obvious sign for a major contribution from hot young stars anywhere in the host galaxy. Rest-frame near-ultraviolet emission aligned along the wide-angle cone of outflowing gas is interpreted as a scattering cone. The outflow has cleared a channel in the dusty host galaxy through which some of the quasar ionizing radiation is able to escape and heat the surrounding interstellar and circumgalactic media. The warm ionized outflow is not powerful enough to impact the host galaxy via mechanical feedback, but radiative feedback by the AGN, aided by the outflow, may help explain the unusually small molecular gas mass fraction in the galaxy host.Comment: 17 pages, 9 figures, accepted for publication in The Astrophysical Journa

Combining Relative Chronology and AMS 14C Dating to Contextualize ‘Megasites’, Serial Migrations and Diachronic Expressions of Material Culture in the Western Tripolye Culture, Ukraine

Scholarship regarding the Eneolithic Cucuteni-Tripolye cultural complex of Romania, Moldova and Ukraine has recently focused on ‘megasites’ of the Western Tripolye culture (WTC) in Central Ukraine. However, in order to properly contextualize such unusual phenomena, we must explore the broader typo-chronology of the WTC, which is suggestive of a high degree of mobility and technological transfer between regions. We report 28 new AMS 14C dates from sites representing diagnostic types and propose a high-resolution chronological sequence for the WTC’s development. Our results support the relative chronology and offer an opportunity to propose a new chronological synthesis for the WTC

The Results of Experimental testing of the Program of Technical and Tactical training of Judo

Хацаюк, О. В. Результати дослідно-експериментальної перевірки програми техніко-тактичної підготовленості дзюдоїстів-ветеранів / Хацаюк О. В., Чередніченко С. В., Дяченко А. А. та ін. // Науковий часопис НПУ імені М. П. Драгоманова. Серія 15: Науково-педагогічні проблеми фізичної культури (фізична культура і спорт). - 2021. - Вип. 7(138). - С. 124-131. - DOI: 10.31392/NPU-nc.series15.2021.7(138).26.Розглянуто питання розроблення спеціалізованого комплексу науково-методичного забезпечення системи багаторічної підготовки дзюдоїстів-ветеранів, що забезпечить формування ефективного техніко-тактичного арсеналу одноборців досліджуваної категорії (із урахуванням їх індивідуально-типологічних, психофізичних особливостей) та сприятиме успішній їх змагальній діяльності. Визначено ефективність експериментальної програми техніко-тактичної підготовленості дзюдоїстів-ветеранів в системі їх річного циклу підготовки. Встановлено, що поетапне формування технічної та тактичної майстерності дзюдоїстів-ветеранів (різних вікових груп та вагових категорій) із урахуванням особливостей річного циклу підготовки забезпечує підвищення показників їх змагальної діяльності, що свідчить про високу ефективність розробленої експериментальної програми.Today it is important to develop a Specialized set of Scientific and Methodological support for long-term training of Veteran Judokas, which will ensure the formation of an effective Technical and Tactical Arsenal of wrestlers of the studied category (taking into account their individual-typological, psychophysical features) and promote their successful Competitive activities. The main Purpose of the study is to determine the effectiveness of the Experimental Program of Technical and Tactical training of Veteran Judokas in the System of their annual Training Cycle. During the Empirical Study, the following methods were used: abstraction, analysis and synthesis, induction and deduction, modeling, expert evaluation method, mathematical and statistical (correlation analysis, factor analysis, scaling), modern scientific tools and more. As a result of Research and Analytical work, members of the Research Group determined the effectiveness of the Experimental Program of Technical and Tactical training of Veteran Judokas in the System of their annual training Cycle. It is established that the gradual Formation of Technical and Tactical skills of Veteran Judokas (different age groups and weight categories) taking into account the peculiarities of the annual training Cycle provides an increase in their competitive activity, which indicates the high efficiency of the Experimental Program. Prospects for Further Research in the chosen direction of Scientific Intelligence include the development of a Pedagogical Model with technical means of teaching the Formation of Readiness of Veteran judokas (women) for competitive activities in the System of their long-term training.Рассмотрены вопросы разработки специализированного комплекса научно-методического обеспечения системы многолетней подготовки дзюдоистов-ветеранов, что обеспечит формирование эффективного технико-тактического арсенала единоборцев изучаемой категории (с учетом их индивидуально-типологических, психофизических особенностей) и будет способствовать успешной их соревновательной деятельности. Определена эффективность экспериментальной программы технико-тактической подготовленности дзюдоистов-ветеранов в системе их годового цикла подготовки. Установлено, что поэтапное формирование технического и тактического мастерства дзюдоистов-ветеранов (различных возрастов и весовых категорий) с учетом особенностей годового цикла подготовки обеспечивает повышение показателей соревновательной деятельности, что свидетельствует о высокой эффективности разработанной экспериментальной программы