Testing a quintessence model with CMBR peaks locations

We show that a model of quintessence with exponential potential, which allows to obtain general exact solutions, can generate location of CMBR peaks which are fully compatible with present observational data

Data Workflow in Large Scale Simulations of Blood Flow in Aneurysms

Aneurysms are responsibile for significant morbidity and mortality, and there is a need for an increased understanding of all the aspects of the natural history of these lesions. We are currently working to extend our analyses with the goal of creating models of aneurysmal progression that are able to predict rupture risk through the description of the evolving geometry, structure, properties, and loads. Realization of patient specific models of the blood circulation necessitates a complex computationally and data intensive procedure that starts from the collection of medical images in a clinical setting and encompasses several stages of data processing on (and transfer to and from) specialized hardware, which include high-performance and visualization clusters as well as consumer workstations and local drives for final storage

Cardiac oxidative stress and inflammatory cytokines response after myocardial infarction

Oxidative stress in heart failure or during ischemia/reperfusion occurs as a result of the excessive generation or accumulation of free radicals or their oxidation products. Free radicals formed during oxidative stress can initiate lipid peroxidation, oxidize proteins to inactive states and cause DNA strand breaks. Oxidative stress is a condition in which oxidant metabolites exert toxic effects because of their increased production or an altered cellular mechanism of protection. In the early phase of acute heart ischemia cytokines have the feature to be functional pleiotropy and redundancy, moreover, several cytokines exert similar and overlapping actions on the same cell type and one cytokine shows a wide range of biological effects on various cell types. Activation of cytokine cascades in the infarcted myocardium was established in numerous studies. In experimental models of myocardial infarction, induction and release of the pro-inflammatory cytokines like TNF-&alpha (Tumor Necrosis Factor &alpha), IL-1&beta (Interleukin- 1&beta) and IL-6 (Interleukin-6) and chemokines are steadily described. The current review examines the role of oxidative stress and pro-inflammatory cytokines response following acute myocardial infarction and explores the inflammatory mechanisms of cardiac injur

A true-time-delay networks design technique

This paper proposes a technique to design wide band switched-line (SL) true-time-delay (TTD) networks, commonly used for phased array antenna (PAA) applications. This study investigates the constant-delay behavior of switched-line phase shifters based on single-pole double-throw (SPDT) switches. Circuit sizing starts by considering the effective S-parameters of the switches, to use their non-idealities as an integral part of the phase shift linearly dependent to the frequency and by considering, from the beginning, the possible spatial positioning of elements that allows the circuit feasibility as a design target. The aim of this study is to provide a technique suitable for the design of well-matched TTD networks with a flat delay in wide bandwidth. In this paper, we propose new design formulas for which we show a single-frequency implementation. A computational strategy is used to obtain numerical solutions of the derived equations with this study. Finally, a monolithic X-band TTD circuit example is shown

"All on short" prosthetic-implant supported rehabilitations

Objectives. Short implants are increasing their popularity among clinicians who want to fulfill the constant demanding of fixed prosthetic solutions in edentulous jaws. The aim of this report was to propose a new possibility to project and realize an occlusal guided implant cross-arch prosthesis supported by ultra-short implants, describing it presented an edentulous mandible case report. Methods. A 61-year-old, Caucasian, female patient who attended the dental clinic of the University of L’Aquila presented with edentulous posterior inferior jaw and periodontitis and periimplantitis processes in the anterior mandible. The remaining tooth and the affected implant were removed. Six 4-mm-long implants were placed to support a cross-arch metal-resin prosthesis. Results. At 1-year follow-up clinical and radiological assessment showed a good osseointegration of the fixtures and the patient was satisfied with the prosthesis solution. Conclusion. The method, even if it requires further validation, seems to be a valid aid in solving lower edentulous clinical cases, and appears less complex and with more indications of other proposals presented in the current clinical literature. Our case report differs from the current technique All-on-Four, which uses four implants in the mandible to support overdenture prosthesis, assuring a very promising clinical resul

Defective Behaviour of an 8T SRAM Cell with Open Defects

The defective behaviour of an 8T SRAM cell with open defects is analyzed. Full and resistive open defects have been considered in the electrical characterization of the defective cell. Due to the similarity between the classical 6T SRAM cell and the 8T cell, only defects affecting the read port transistors have been considered. In the work, it is shown how an open in a defective cell may influence the correct operation of a victim cell sharing the same read circuitry. Also, it is shown that the sequence of bits written on the defective cell prior to a read action can mask the presence of the defect. Different orders of critical resistance have been found depending on the location of the open defect. A 45nm technology has been used for the illustrative example presented in the wor

Predicting the Blur Visual Discomfort for Natural Scenes by the Loss of Positional Information

The perception of the blur due to accommodation failures, insufficient optical correction or imperfect image reproduction is a common source of visual discomfort, usually attributed to an anomalous and annoying distribution of the image spectrum in the spatial frequency domain. In the present paper, this discomfort is attributed to a loss of the localization accuracy of the observed patterns. It is assumed, as a starting perceptual principle, that the visual system is optimally adapted to pattern localization in a natural environment. Thus, since the best possible accuracy of the image patterns localization is indicated by the positional Fisher Information, it is argued that the blur discomfort is strictly related to a loss of this information. Following this concept, a receptive field functional model, tuned to common features of natural scenes, is adopted to predict the visual discomfort. It is a complex-valued operator, orientation-selective both in the space domain and in the spatial frequency domain. Starting from the case of Gaussian blur, the analysis is extended to a generic type of blur by applying a positional Fisher Information equivalence criterion. Out-of-focus blur and astigmatic blur are presented as significant examples. The validity of the proposed model is verified by comparing its predictions with subjective ratings. The model fits linearly with the experiments reported in independent databases, based on different protocols and settings.Comment: 12 pages, 8 figures, article submitted to Vision Research (Elsevier) Journal in July 202

Predicting blur visual discomfort for natural scenes by the loss of positional information

The perception of blur due to accommodation failures, insufficient optical correction or imperfect image reproduction is a common source of visual discomfort, usually attributed to an anomalous and annoying distribution of the image spectrum in the spatial frequency domain. In the present paper, this discomfort is related to a loss of the localization accuracy of the observed patterns. It is assumed, as a starting perceptual principle, that the visual system is optimally adapted to pattern localization in a natural environment. Thus, since the best possible accuracy of the image patterns localization is indicated by the positional Fisher Information, it is argued that blur discomfort is strictly related to a loss of this information. Following this concept, a receptive field functional model is adopted to predict the visual discomfort. It is a complex-valued operator, orientation-selective both in the space domain and in the spatial frequency domain. Starting from the case of Gaussian blur, the analysis is extended to a generic type of blur by applying a positional Fisher Information equivalence criterion. Out-of-focus blur and astigmatic blur are presented as significant examples. The validity of the proposed model is verified by comparing its predictions with subjective ratings. The model fits linearly with the experiments reported in independent databases, based on different protocols and settings

Answer to the remarks on superconductivity in PdH

Abstract This is the answer to the letter of Baranowski and Debowska [Baranowski and Debowska, J. Alloys Compd. 437 (2007) L4–L5]