The role of internalized transphobia, loneliness, and social supportin thepsychological well-being of a group of Italian transgender and gender non-conforming youths: A moderated-mediation model

The contribution investigates the quality of life of transgender and gender non-conforming (TGNC)people in according to the support received from social and family context. Although TGNC youth represent a highly resilient community capable of successfully overcoming adverse life circumstances, they still experience social stigma that negatively impacts their health (Molnar, 2018), especially if approached to the possibility of being rejectedby the family and peer group.An additional risk is represented by the common idea that the sex assigned at birth must be aligned with gender identity (Nadal et al., 2012) on which the support (Lev, 2013) can play a role as a moderator. Objectives of thisresearch are:1) evaluating how internalized transphobia (IT) and loneliness are correlated withthe quality of life; 2) clarifying whether social support would act as a protective factor in the quality of life of research participants. The research used a multimethod approach through a questionnaire divided into 5 sections including 4 different scales (Warwick–Edinburgh Mental Well-being Scale; Gender Minority Stress and Resilience Scale; Multidimensional Scale of Perceived Social Support; Scala Revised University of California at Los Angeles Loneliness Scale). Thus, within the framework of the minority stress, this paper aims to investigate the role of loneliness as a mediator of the relationship between IT and psychological well-being (PW), as well as the moderating role of social support. A total of 79 Italian TGNC youths (45 binary and 34 non binary) aged 18 to 30 years (M = 23.73, SD = 3.59) participated in an online survey. A moderated mediation model was tested using the PROCESS Macro for SPSS with gender identity and age as control variables. Results showed that: (1)IT was negatively associated with PW(b = -0.03, p = 0.001); (2) IT was positively associated with loneliness (b = 0.03, p< 0.001); (3) loneliness was negatively associated with PW(b = -0.49, p = 0.001); and (4) loneliness partially mediated the relationship between IT and PW(b = -0.19, p = 0.006). In addition, social support proved to be a significant moderator, as the effect of IT on PW decreased with moderate (b = -0.03, 95% C.I. [-0.04, -0.01], p = 0.001) and high social support (b = -0.04, 95% C.I. [-0.06, -0.01], p < 0.001), but not with low (p< 0.05). Other clinical and social implications of our findings are discussed in terms of individual, interpersonal, and structural stigma.Based on our findings, it is advisable both to expand the social network, promoting intimate and community relationships, and to take charge, on a clinical level, of the experiences of loneliness that can become radicalized over time also through the early experiences of one's personal and family history

The Role of Internalized Transphobia, Loneliness, and Social Support in the Psychological Well-Being of a Group of Italian Transgender and Gender Non-Conforming Youths

Although transgender and gender non-conforming (TGNC) youth represent a highly resilient community capable of successfully overcoming adverse life circumstances, they still face social stigma that negatively impacts their health, being at risk of developing negative feelings toward their own TGNC identity (i.e., internalized transphobia). A poorly investigated dimension in TGNC health research is perceived loneliness. Thus, within the minority stress theory, the present study aimed to investigate the mediating role of loneliness and the moderating role of social support in the relationship between internalized transphobia and psychological well-being among 79 Italian TGNC youths aged 18 to 30-years-old who participated in an online survey. The main results show that loneliness partially mediated the relationship between internalized transphobia and psychological well-being. In addition, social support emerged as a significant moderator, as the impact of internalized transphobia on psychological well-being decreased at moderate and high levels of social support, but not at low levels. The findings have significant implications for clinical practice and psychosocial interventions to reduce the impact of internalized stigma and stress on psychological healt

The Role of Internalized Transphobia, Loneliness, and Social Support in the Psychological Well-Being of a Group of Italian Transgender and Gender Non-Conforming Youths

lthough transgender and gender non-conforming (TGNC) youth represent a highly resilient community capable of successfully overcoming adverse life circumstances, they still face social stigma that negatively impacts their health, being at risk of developing negative feelings toward their own TGNC identity (i.e., internalized transphobia). A poorly investigated dimension in TGNC health research is perceived loneliness. Thus, within the minority stress theory, the present study aimed to investigate the mediating role of loneliness and the moderating role of social support in the relationship between internalized transphobia and psychological well-being among 79 Italian TGNC youths aged 18 to 30-years-old who participated in an online survey. The main results show that loneliness partially mediated the relationship between internalized transphobia and psychological well-being. In addition, social support emerged as a significant moderator, as the impact of internalized transphobia on psychological well-being decreased at moderate and high levels of social support, but not at low levels. The findings have significant implications for clinical practice and psychosocial interventions to reduce the impact of internalized stigma and stress on psychological health

Quali sono i fattori di successo delle famiglie multilingue? La relazione tra atteggiamenti linguistici e dinamiche familiari e di comunità

The article focuses on the emotional, cognitive, and social climate in which multilingual families make and influence language choices. It investigates what impact the choices can have on the general well-being of the family, regarding both the intergenerational relationship and the community context. The research suggests that the linguistic attitudes of migrant families can stimulate and implement potential well-being. It consists of the conscious management of the specific and complex dynamic activated in a multilingual family

The photo diaries method to catch the daily experience of Italian university students during COVID-19 lockdown

The aim of this research was to explore Italian students’ lockdown experience during the COVID-19 pandemic to understand their emotions and the coping strategies they played out during their daily lives at home through photo diaries. The research was carried out in six Italian universities involving 109 participants. The task required each student to take one photo per day for one week in T1 and one in T2, representing their mood during their daily life at home and to give it a title and a brief description. Overall, 1,526 photographs with texts were collected. The main subjects of the photographs were objects, the most frequent coping strategy was self-distraction, and most participants expressed emotions of joy and anticipation but also sadness and fear. Then, the associations between the characteristics of their photos and the emotions and coping strategies from their diary entries were analyzed. For example, emotional support and joy were positively associated with family, pets, and food, while fear and sadness were represented with objects. Implications of the results are discussed, including considerations about using photo diaries during collective disasters

Direct sunlight facility for testing and research in HCPV

A facility for testing different components for HCPV application has been developed in the framework of “Fotovoltaico ad Alta Efficienza” (FAE) project funded by the Sicilian Regional Authority (PO FESR Sicilia 2007/2013 4.1.1.1). The testing facility is equipped with an heliostat providing a wide solar beam inside the lab, an optical bench for mounting and aligning the HCPV components, electronic equipments to characterize the I-V curves of multijunction cells operated up to 2000 suns, a system to circulate a fluid in the heat sink at controlled temperature and flow-rate, a data logging system with sensors to measure temperatures in several locations and fluid pressures at the inlet and outlet of the heat sink, and a climatic chamber with large test volume to test assembled HCPV modules

Very Early PSA Response to Abiraterone in mCRPC Patients: A Novel Prognostic Factor Predicting Overall Survival

BACKGROUND Abiraterone Acetate (AA) is approved for the treatment of mCRPC after failure of androgen deprivation therapy in whom chemotherapy is not yet clinically indicated and for treatment of mCRPC progressed during or after docetaxel-based chemotherapy regimen. The aim of this study is to evaluate the role of early PSA decline for detection of therapy success or failure in mCRPC patients treated with AA in post chemotherapy setting.PATIENTS AND METHODS We retrospectively evaluated 87 patients with mCRPC treated with AA. Serum PSA levels were evaluated after 15, 90 days and then monthly. The PSA flare phenomenon was evaluated, according to a confirmation value at least one week apart. The primary endpoint was to demonstrate that an early PSA decline correlates with a longer progression free survival (PFS) and overall survival (OS). The secondary endpoind was to demonstrate a correlation between better outcome and demographic and clinical patient characteristics.RESULTS We have collected data of 87 patients between Sep 2011 and Sep 2014. Early PSA response (≥ 50% from baseline at 15 days) was found in 56% evaluated patients and confirmed in 29 patients after 90 days. The median progression free survival (PFS) was 5,5 months (4,6-6,5) and the median overall survival (OS) was 17,1 months (8,8-25,2). In early responders patients (PSA RR ≥ 50% at 15 days), we found a significant statistical advantage in terms of PFS at 1 year, HR 0.28, 95%CI 0.12-0.65, p=0.003, and OS, HR 0.21 95% CI 0.06-0.72, p=0.01. The results in PFS at 1 years and OS reached statistical significance also in the evaluation at 90 days.CONCLUSION A significant proportion (78.6%) of patients achieved a rapid response in terms of PSA decline. Early PSA RR (≥ 50% at 15 days after start of AA) can provide clinically meaningful information and can be considered a surrogate of longer PFS and OS

Influence of LV Neutral Grounding on Global Earthing Systems

International Standards define a Global Earthing System as an earthing net created interconnecting local Earthing Systems (generally through the shield of MV cables and/or bare buried conductors). In Italy, the regulatory authority for electricity and gas requires distributors to guarantee the electrical continuity of LV neutral conductor. This requirement has led to the standard practice of realizing “reinforcement groundings” along the LV neutral conductor path and at users' delivery cabinet. Moreover, in urban high-load scenarios (prime candidates to be part of a Global Earthing System), it is common that LV distribution scheme creates, through neutral conductors, an effective connection between grounding systems of MV/LV substations, modifying Global Earthing System consistency. The aim of this paper is to evaluate the effect, in terms of electrical safety, of the aforementioned LV neutral distribution scheme when an MV-side fault to ground occurs. For this purpose, simulations are carried out on a realistic urban test case and suitable evaluation indexes are proposed

Prospective validation of the CLIP score: a new prognostic system for patient with cirrhosis and hepatocellular carcinoma

Prognosis of patients with cirrhosis and hepatocellular carcinoma (HCC) depends on both residual liver function and tumor extension. The CLIP score includes Child-Pugh stage, tumor morphology and extension, serum alfa-fetoprotein (AFP) levels, and portal vein thrombosis. We externally validated the CLIP score and compared its discriminatory ability and predictive power with that of the Okuda staging system in 196 patients with cirrhosis and HCC prospectively enrolled in a randomized trial. No significant associations were found between the CLIP score and the age, sex, and pattern of viral infection. There was a strong correlation between the CLIP score and the Okuda stage, As of June 1999, 150 patients (76.5%) had died. Median survival time was 11 months, overall, and it was 36, 22, 9, 7, and 3 months for CLIP categories 0, 1, 2, 3, and 4 to 6, respectively. In multivariate analysis, the CLIP score had additional explanatory power above that of the Okuda stage. This was true for both patients treated with locoregional therapy or not. A quantitative estimation of 2-year survival predictive power showed that the CLIP score explained 37% of survival variability, compared with 21% explained by Okuda stage. In conclusion, the CLIP score, compared with the Okuda staging system, gives more accurate prognostic information, is statistically more efficient, and has a greater survival predictive power. It could be useful in treatment planning by improving baseline prognostic evaluation of patients with RCC, and could be used in prospective therapeutic trials as a stratification variable, reducing the variability of results owing to patient selection