Shear-lag analysis of a hybrid, unidirectional composite with fiber damage

Development of a method of analysis capable of predicting accurately the fracture behavior of unidirectional hybrid (buffer strip) composite laminates was studied. Three particular solutions are discussed in detail: broken fibers in a unidirectional half-plane; adjoined half planes of different fiber and matrix properties; and the solution of two half planes bounding a third distinct region of finite width. This finite width region represents a buffer strip and primary attention is given to the potential of this strip to arrest a crack that originates in one of the half planes. A materials modeling approach using the classical shear lag assumption to describe the stress transfer between fibers was analyzed. Explicit fiber and matrix properties of the three regions are retained, and changes in the laminate behavior as a function of the relative material properties, buffer strip width, and initial crack length are discussed

Analysis of a hybrid-undirectional buffer strip laminate

A method of analysis capable of predicting accurately the fracture behavior of a unidirectional composite laminate containing symmetrically placed buffer strips is presented. As an example, for a damaged graphite/epoxy laminate, the results demonstrate the manner in which to select the most efficient combination of buffer strip properties necessary to inhibit crack growth. Ultimate failure of the laminate after the arrest can occur under increasing load either by continued crack extension through the buffer strips or the crack can jump the buffer strips. For some typical hybrid materials it is found that a buffer strip spacing to width ratio of about four to one is the most efficient

Mathematical modeling of damage in unidirectional composites

A review of some approximate analytical models for damaged, fiber reinforced composite materials is presented. Using the classical shear lag stress displacement assumption, solutions are presented for a unidirectional laminate containing a notch, a rectangular cut-out, and a circular hole. The models account for longitudinal matrix yielding and splitting as well as transverse matrix yielding and fiber breakage. The constraining influence of a cover sheet on the unidirectional laminate is also modeled

On the recurrence of Noctiluca scintillans bloom in Minnie Bay, Port Blair: Impact on water quality and bioactivity of extracts

A Noctiluca scintillans bloom in the coastal waters of Minnie Bay, Port Blair was studied. Physico-chemical and biological properties of bloom-infested waters were monitored during the bloom period lasting five days. The bloom appeared as a green streak along the entire coastline of Minnie Bay, with cell counts of 17 103 cells/ l. The bloom appeared as a sudden spurt in cell number and persisted for a period of 48 h. The antibacterial properties of extracts from this algal species were also investigated. Conspicuously, the bloom inhibited the common resident phytoplankton species. Total suspended solids showed a marked increase during day-one of bloom compared to ambient levels. The bloom appeared to be limited by dissolved inorganic nitrogen species availability. The differential growth of phytoplankton reveals the involvement of specific trigger factors for such blooms. From the present viewpoint, micro-scale studies on hydrobiological factors preceding the onset of bloom would reveal what cycle of events lead to a bloom and the causal factors of such blooms. However, prediction of occurrence of such blooms and in situ measurements are practical difficulties to be addressed. Since a similar bloom was reported earlier in 2001, it is worthwhile to keep a watch and investigate as to whether there is any anthropogenic or environmental cause for the recurrence of the bloom

Vitamin A Deficiency after Gastric Bypass Surgery: An Underreported Postoperative Complication

Introduction. Few data are available on vitamin A deficiency in the gastric bypass population. Methods. We performed a retrospective chart review of gastric bypass patients (n = 69, 74% female). The relationship between serum vitamin A concentration and markers of protein metabolism at 6-weeks and 1-year post-operative were assessed. Results. The average weight loss at 6-weeks and 1-year following surgery was 20.1 ± 9.1 kg and 44.1 ± 17.1 kg, respectively. At 6 weeks and 1 year after surgery, 35% and 18% of patients were vitamin A deficient, (<325 mcg/L). Similarly, 34% and 19% had low pre-albumin levels (<18 mg/dL), at these time intervals. Vitamin A directly correlated with pre-albumin levels at 6 weeks (r = 0.67, P < 0.001) and 1-year (r = 0.67,  P < 0.0001). There was no correlation between the roux limb length measurement and pre-albumin or vitamin A serum concentrations at these post-operative follow-ups. Vitamin A levels and markers of liver function testing were also unrelated. Conclusion. Vitamin A deficiency is common after bariatric surgery and is associated with a low serum concentration of pre-albumin. This fat-soluble vitamin should be measured in patients who have undergone gastric bypass surgery and deficiency should be suspected in those with evidence of protein-calorie malnutrition

Pharmacoinformatic investigation of medicinal plants from East Africa

Medicinal plants have widely been used in the traditional treatment of ailments and have been proven effective. Their contribution still holds an important place in modern drug discovery due to their chemical, and biological diversities. However, the poor documentation of traditional medicine, in developing African countries for instance, can lead to the loss of knowledge related to such practices. In this study, we present the Eastern Africa Natural Products Database (EANPDB) containing the structural and bioactivity information of 1870 unique molecules isolated from about 300 source species from the Eastern African region. This represents the largest collection of natural products (NPs) from this geographical region, covering literature data of the period from 1962 to 2019. The computed physicochemical properties and toxicity profiles of each compound have been included. A comparative analysis of some physico-chemical properties like molecular weight, H-bond donor/acceptor, logP(o/w), etc. as well scaffold diversity analysis has been carried out with other published NP databases. EANPDB was combined with the previously published Northern African Natural Products Database (NANPDB), to form a merger African Natural Products Database (ANPDB), containing similar to 6500 unique molecules isolated from about 1000 source species (freely available at http://african-compounds.org). As a case study, latrunculins A and B isolated from the spongeNegombata magnifica(Podospongiidae) with previously reported antitumour activities, were identified via substructure searching as molecules to be explored as putative binders of histone deacetylases (HDACs)

Search for low-mass dark matter via bremsstrahlung radiation and the Migdal effect in SuperCDMS

We present a new analysis of previously published SuperCDMS data using a profile likelihood framework to search for sub-GeV dark matter (DM) particles through two inelastic scattering channels: bremsstrahlung radiation and the Migdal effect. By considering these possible inelastic scattering channels, experimental sensitivity can be extended to DM masses that are undetectable through the DM-nucleon elastic scattering channel, given the energy threshold of current experiments. We exclude DM masses down to 220  MeV/c2 at 2.7×10−30  cm2 via the bremsstrahlung channel. The Migdal channel search provides overall considerably more stringent limits and excludes DM masses down to 30  MeV/c2 at 5.0×10−30  cm2

First measurement of the nuclear-recoil ionization yield in silicon at 100 eV

We measured the nuclear--recoil ionization yield in silicon with a cryogenic phonon-sensitive gram-scale detector. Neutrons from a mono-energetic beam scatter off of the silicon nuclei at angles corresponding to energy depositions from 4\,keV down to 100\,eV, the lowest energy probed so far. The results show no sign of an ionization production threshold above 100\,eV. These results call for further investigation of the ionization yield theory and a comprehensive determination of the detector response function at energies below the keV scale

A Search for Low-mass Dark Matter via Bremsstrahlung Radiation and the Migdal Effect in SuperCDMS

We present a new analysis of previously published of SuperCDMS data using a profile likelihood framework to search for sub-GeV dark matter (DM) particles through two inelastic scattering channels: bremsstrahlung radiation and the Migdal effect. By considering these possible inelastic scattering channels, experimental sensitivity can be extended to DM masses that are undetectable through the DM-nucleon elastic scattering channel, given the energy threshold of current experiments. We exclude DM masses down to $220~\textrm{MeV}/c^2$ at $2.7 \times 10^{-30}~\textrm{cm}^2$ via the bremsstrahlung channel. The Migdal channel search provides overall considerably more stringent limits and excludes DM masses down to $30~\textrm{MeV}/c^2$ at $5.0 \times 10^{-30}~\textrm{cm}^2$.Comment: Submitted to PR