683 research outputs found

    Survey on Security User Data in Local Connectivity Using Multicast Key Agreement

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    In this paper, we study Group key agreement means multiple parties want to create a common secret key to be used to exchange information securely. The group key agreement with an arbitrary connectivity graph, where each user is only aware of his neighbor and has no information about the existence of other users. Further, he has no information about the network topology. We implement the existing system with more time efficient manner and provide a multicast key generation server which is expected in future scope by current authors. We replace the Diffie Hellman key exchange protocol by a new multicast key exchange protocol that can work with one to one and one to many functionality. We also tend to implement a strong symmetric encryption for improving file security in the system

    Efficiency in MANET Systems using Energy efficient encryption algorithm

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    In this paper, we study Group key agreement means multiple parties want to create a common secret key to be used to exchange information securely. The group key agreement with an arbitrary connectivity graph, where each user is only aware of his neighbor and has no information about the existence of other users. Further, he has no information about the network topology. We implement the existing system with more time efficient manner and provide a multicast key generation server which is expected in future scope by current authors. We replace the Diffie Hellman key exchange protocol by a new multicast key exchange protocol that can work with one to one and one to many functionality. We also tend to implement a strong symmetric encryption for improving file security in the s

    Comparative study of different materials used for manufacturing of an automobile body

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    The fast growing demand for more fuel-efficient vehicles to reduce energy consumption and air pollution is a challenge for the automotive industry. The weight reduction is considered as a leading key in upgrading the fuel economy. The Varity of different materials can be found within vehicle body including steel, magnesium alloys, plastics alloys and aluminium alloys .Aluminium alloy is more significant as compared to other material because of strength, weight and anti-corrosion as well as cost wise the aluminium alloy material cost is less than carbon fibre reinforced plastics. The objective of this paper is comparative study of different materials uses for manufacturing the automobile body and their performance. This study is useful to understand different materials performance in automobile body and their benefits. This study is an attempt to cover all variety of up-to date body materials, and highlight the most promising of them for volume production was committed on small scale industry

    Numerical Simulation of a Ludwieg-tube Fuel Delivery System for Scramjet Experiments in Shock Tunnels

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    The T4 shock tunnel at The University of Queensland is regularly used to perform supersonic combustion experiments. The fuel for the test model is supplied using a Ludwieg-tube delivery system. A combination of theoretical modelling and calibration tests is used to determine the mass flow-rate of fuel for given Ludwieg tube initials conditions and the measured pressure in the plenum chamber that supplies the fuel to the model. The theoretical model used in the calibration procedure is presented. The goal of this project is to check the suitability of the modelling assumptions by simulating the complete Ludwieg-tube system using the one-dimensional Lagrangian computer code, L1d. Simulation of the fuel delivery system is done separately for viscous and inviscid flow with conditions replicating those used in supersonic combustion tests in T4. The steady plenum pressures from the simulations of inviscid and viscous flow are, on average, within ±7% and ±4%, respectively, of the values measured experimentally. Further, the fuel mass flow-rates obtained from viscous simulations are, on average, within ±13% of the experimental values

    Velocity slice imaging for dissociative electron attachment

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    A velocity slice imaging method is developed for measuring the angular distribution of fragment negative ions arising from dissociative electron attachment (DEA) to molecules. A low energy pulsed electron gun, a pulsed field ion extraction, and a two-dimensional position sensitive detector consisting of microchannel plates and a wedge-and-strip anode are used for this purpose. Detection and storage of each ion separately for its position and flight time allows analysis of the data offline for any given time slice, without resorting to pulsing the detector bias. The performance of the system is evaluated by measuring the angular distribution of O− from O2 and comparing it with existing data obtained using conventional technique. The capability of this technique in obtaining forward and backward angular distribution data is shown to have helped in resolving one of the existing problems in the electron scattering on O2

    Late systolic central hypertension as a predictor of incident heart failure : the Multi-Ethnic Study of Atherosclerosis

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    Background: Experimental studies demonstrate that high aortic pressure in late systole relative to early systole causes greater myocardial remodeling and dysfunction, for any given absolute peak systolic pressure. Methods and Results: We tested the hypothesis that late systolic hypertension, defined as the ratio of late (last one third of systole) to early (first two thirds of systole) pressure-time integrals (PTI) of the aortic pressure waveform, independently predicts incident heart failure (HF) in the general population. Aortic pressure waveforms were derived from a generalized transfer function applied to the radial pressure waveform recorded noninvasively from 6124 adults. The late/early systolic PTI ratio (L/ESPTI) was assessed as a predictor of incident HF during median 8.5 years of follow-up. The L/ESPTI was predictive of incident HF (hazard ratio per 1% increase= 1.22; 95% CI= 1.15 to 1.29; P58.38%) was more predictive of HF than the presence of hypertension. After adjustment for each other and various predictors of HF, the HR associated with hypertension was 1.39 (95% CI= 0.86 to 2.23; P=0.18), whereas the HR associated with a high L/E was 2.31 (95% CI=1.52 to 3.49; P<0.0001). Conclusions: Independently of the absolute level of peak pressure, late systolic hypertension is strongly associated with incident HF in the general population

    Identification of New Drug Candidates Against \u3cem\u3eBorrelia burgdorferi\u3c/em\u3e Using High-Throughput Screening

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    Lyme disease is the most common zoonotic bacterial disease in North America. It is estimated that .300,000 cases per annum are reported in USA alone. A total of 10%–20% of patients who have been treated with antibiotic therapy report the recrudescence of symptoms, such as muscle and joint pain, psychosocial and cognitive difficulties, and generalized fatigue. This condition is referred to as posttreatment Lyme disease syndrome. While there is no evidence for the presence of viable infectious organisms in individuals with posttreatment Lyme disease syndrome, some researchers found surviving Borrelia burgdorferi population in rodents and primates even after antibiotic treatment. Although such observations need more ratification, there is unmet need for developing the therapeutic agents that focus on removing the persisting bacterial form of B. burgdorferi in rodent and nonhuman primates. For this purpose, high-throughput screening was done using BacTiter-Glo assay for four compound libraries to identify candidates that stop the growth of B. burgdorferi in vitro. The four chemical libraries containing 4,366 compounds (80% Food and Drug Administration [FDA] approved) that were screened are Library of Pharmacologically Active Compounds (LOPAC1280), the National Institutes of Health Clinical Collection, the Microsource Spectrum, and the Biomol FDA. We subsequently identified 150 unique compounds, which inhibited .90% of B. burgdorferi growth at a concentration of ,25 µM. These 150 unique compounds comprise many safe antibiotics, chemical compounds, and also small molecules from plant sources. Of the 150 unique compounds, 101 compounds are FDA approved. We selected the top 20 FDA-approved molecules based on safety and potency and studied their minimum inhibitory concentration and minimum bactericidal concentration. The promising safe FDA-approved candidates that show low minimum inhibitory concentration and minimum bactericidal concentration values can be chosen as lead molecules for further advanced studies
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