176 research outputs found
FIND KEY TO EFFICIENT AND EXPRESSIVE WAY AROUND DATA ENCRYPTION IN THE CLOUD
We propose a file encryption scheme with a hierarchical attribute for specialized files in cloud computing. We recommend the layer type of the access structure to solve the problem of multiple series files that are discussed. We carry out and implement a comprehensive test of the FH-Club penguin-ABE plan. In the existing system, the cost and time to encrypt files is high, the system understands some time and the cost of the expenses is too high. The access structure to the layer is integrated into a single access structure, and then the hierarchical files are encrypted using the integrated access architecture. The encrypted text components associated with the attributes can be shared through files. The penguin-ABE systems of the club are achievable and have a lot of versatility and, therefore, are more suitable for general applications. Several hierarchical discussion files are resolved using the Layer Type access structure. In the proposed system, the encryption text storage and the file encryption time are stored. As the files grow, the benefits of our plan become clearer. Therefore, the storage of encryption text and the price of encryption time of the files are stored. In addition, the proposed plan has proven to be safe under the normative assumption
Double blind randomized comparative study of transdermal fentanyl patch for post operative pain relief in major abdominal surgery as a component of multimodal analgesic therapy
Background: There are various methods of alleviating post-operative pain, multimodal analgesia is the recommended practice. Fentanyl patch can also be used in the management of acute postoperative pain. We have done a study to compare the efficacy of fentanyl patch to a placebo patch as a part of multimodal analgesic strategy.Methods: Forty four patients were randomized into two groups. Groups were named as FP (Fentanyl patch) and P (Placebo). The Patch was placed 10-12 hours before surgery and patient was monitored for 72 hours postoperatively for pain by NRS (Numeric Rating Scale). All the patients received regular Paracetamol and Diclofenac Sodium. Tramadol was given as rescue analgesia if the NRS scale was more than 5. Data was analysed using Windows stat version 9.2 from Indostat services.Results: There was statistically significant difference in the consumption of Tramadol in patients with FP group (19.44 mg) as compared to P group (72.22mg) over 72 hours. The Numerical Rating scale was also much lower in the FP group at 8, 16, 24, 32, 40, 48, 56, 64 and 72 hours. Maximum difference in the pain score being at 24 hours for the FP group. No difference in the Sedation, Pruritus, Respiratory depression, Nausea and vomiting scores in the two groups.Conclusions: Transdermal Fentanyl Patch of 25 µg/hr when applied 10-12 hours before surgery provides effective postoperative pain relief after major abdominal surgery as a part of multimodal analgesia
सिंचाई व्य्वस्थाओं के साथ मछ्ली पालन का एकीकरण - एक नया व्य्वस्थित दृष्टिकोण
कृपया पूरा लेख पढे
Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI
BACKGROUND: A number of gene therapy applications would benefit from vectors capable of expressing multiple genes. In this study we explored the feasibility and efficiency of expressing two or three transgenes in HIV-1 based lentiviral vector. Bicistronic and tricistronic self-inactivating lentiviral vectors were constructed employing the internal ribosomal entry site (IRES) sequence of encephalomyocarditis virus (EMCV) and/or foot-and-mouth disease virus (FMDV) cleavage factor 2A. We employed enhanced green fluorescent protein (eGFP), O(6)-methylguanine-DNA-methyltransferase (MGMT), and homeobox transcription factor HOXB4 as model genes and their expression was detected by appropriate methods including fluorescence microscopy, flow cytometry, immunocytochemistry, biochemical assay, and western blotting. RESULTS: All the multigene vectors produced high titer virus and were able to simultaneously express two or three transgenes in transduced cells. However, the level of expression of individual transgenes varied depending on: the transgene itself; its position within the construct; the total number of transgenes expressed; the strategy used for multigene expression and the average copy number of pro-viral insertions. Notably, at limiting MOI, the expression of eGFP in a bicistronic vector based on 2A was ~4 times greater than that of an IRES based vector. CONCLUSION: The small and efficient 2A sequence can be used alone or in combination with an IRES for the construction of multicistronic lentiviral vectors which can express encoded transgenes at functionally relevant levels in cells containing an average of one pro-viral insert
Impact Assessment of ‘Bhoochetana’ – A Soil Test-Based Nutrient Management Scaling-Out Initiative in Karnataka
A study was conducted during rabi 2014 to assess the impact of ‘Bhoochetana’, a soil test-based fertilizer management initiative in Karnataka, India. In selected six villages across Raichur, Deodurga, Manvi and Lingasugur blocks of Raichur district in Karnataka, India, soil samples and crop yield data were collected from farmers’ fields having farmer practice (FP) of blanket application of nitrogen (N), phosphorus (P) and potassium (K), as well as improved practice (IP) of soil test-based application of N, P and K along with deficient sulphur (S), boron (B) and zinc (Zn) as recommended under ‘Bhoochetana’. After five years (since 2010) of ‘Bhoochetana’ in Raichur district, significant improvement in soil health is noted in IP adopted plots. In five out of six villages, soil organic carbon under IP increased to medium (0.50% to 0.71%) levels as compared with low (0.26% to 0.43%) levels observed under FP. Soil fertility under IP improved in terms of macro and micro nutrients like N, P, K, S, B and Zn. Increase in crop yield of all major crops like cotton (19%), groundnut (17%), pigeonpea (13%), sorghum (11%), and sunflower (11%) was observed under IP
Engaging with sustainability issues in metropolitan Chennai : city report
Chennai is the largest metropolitan city in South India (8.7 million in 2011) and the provincial capital of the large state of Tamil Nadu (population 72 million in 2011). Before that, under British rule, the city was the capital of the Madras Presidency, and was known as Madras until 1996, when the name was officially changed to Chennai. Located on the east coast of India, on the Bay of Bengal, sea trade has been an important aspect of the regional economy since at least the colonial period. Still today, the city combines political functions with economic command functions for both manufacturing and services, reflecting the region's diversified economy. The Chennai metropolitan area has witnessed strong growth over the last 20 years in automobile manufacturing, software services, hardware manufacturing, healthcare and financial services (CDP 2009). However, it should be noted that only 30% of total employment in the city takes place in the formal sector i.e., is covered by contracts and labour laws, the remaining 70% falls in the informal sector. This underscores the importance of small and micro enterprises and self-employment for providing goods, services and livelihoods in the local economy
Are textbook lungs really normal? A cadaveric study on the anatomical and clinical importance of variations in the major lung fissures, and the incomplete right horizontal fissure.
INTRODUCTION: The lungs have three main fissures: the right oblique fissure (ROF), right horizontal fissure (RHF), and left oblique fissure (LOF). These can be complete, incomplete or absent; quantifying the degree of completeness of these fissures is novel. Standard textbooks often refer to the fissures as complete, but awareness of variation is essential in thoracic surgery. MATERIALS AND METHODS: Fissures in 81 pairs of cadaveric lungs were classified. Oblique fissures were measured from lung hila posteriorly to the lung hila anteriorly; and the RHF measured from the ROF to the anteromedial lung edge. The degree of completeness of fissures was expressed as a percentage of the total projected length were they to be complete. The frequency and location of accessory fissures was noted. RESULTS: LOF were complete in 66/81 (81.5%), incomplete in 13/81 (16.0%) and absent in 2/81 (2.47%); ROF were complete in 52/81 (64.2%), incomplete in 29/81 (35.8%) and never absent; RHF were more variable, complete in 18/81 (22.2%), incomplete in 54/81 (66.7%) and absent in 9/81 (11.1%). LOF and ROF were on average 97.1% and 91.6% complete, respectively, being deficient posteriorly at the lung hila. The RHF on average 69.4% complete, being deficient anteromedially. There were accessory fissures in 10 left and 19 right lungs. CONCLUSIONS: This study provides a projection of the anatomy thoracic surgeons may encounter at operation, in particular the variable RHF. This knowledge is essential for optimal outcomes in both benign and oncological procedures influenced by the fissures
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