Evaluasi Pelaksanaan Konseling Menyusui

Salah satu upaya pemerintah dalam meningkatkan pemberian ASI di Indonesia adalah dengan memberikan konseling menyusui di pelayanan kesehatan. Penelitian perlu dilakukan untuk mengevaluasi pelaksanaan konseling menyusui di Kota Jambi dengan mengeksplorasi komponen input, activity, output, dan outcome. Penelitian ini merupakan penelitian kualitatif menggunakan strategi studi kasus. Penelitian dilakukan di empat puskesmas Kota Jambi pada bulan Desember 2013 sampai dengan Februari 2014. Pengumpulan data dilakukan dengan studi dokumen, observasi pelaksanaan konseling menyusui dan sarana prasarana, wawancara mendalam, serta focus group discussion. Analisis data yang digunakan adalah analisis tematik. Hasil penelitian menunjukkan bahwa komponen input dan activity kurang optimal seperti kurangnya sumber daya manusia, keterbatasan sarana prasarana, belum ada petunjuk teknis pelaksanaan konseling menyusui, belum ada pemantauan pascapelatihan, kurangnya komitmen personal konselor, belum ada penegasan program, serta lemahnya pengawasan. Komponen output masih kurang baik, terlihat pada belum terdapat data jumlah klien yang diberi konseling menyusui dan jumlah monitoring/supervisi. Komponen outcome menunjukkan bahwa kepuasan klien konseling menyusui kurang. Pelaksanaan konseling menyusui di Kota Jambi masih kurang optimal. Terlihat dari komponen input masih kurang memadai, komponen activity belum berjalan optimal, sedangkan komponen output dan komponen outcome belum mencapai hasil yang diharapkan.The government's efforts in improving breastfeeding in Indonesia is to provide breastfeeding counseling services in health care especially at primary health care centre. Therefore it is necessary to evaluate the implementation of breastfeeding counseling in the City of Jambi by exploring its input, activity, output, and outcomes components. This study was a qualitative research using case study strategy. The study was conducted in four health centers City of Jambi during December 2013 to February 2014. Data were collected through document study, breastfeeding counseling and execution infrastructure observation, in-depth interviews, and focus group discussion. Data analysis includes transcription, reduction, coding, categorizing, themes, and interpretation of research results. The results showed that the component inputs and activity were not done optimally due to a lack of human resources, infrastructure limitations, unavailability of technical guidelines, non-existence of post training monitoring or supervision, lack of counselor's personal commitment, lack of program clarity, as well as poor management and supervision of the health department. Aservice output were not also good as indicated by data unavailability of clients served and none of monitoring has been conducted. Outcome component showed that there were still a lack of client satisfaction and resolved breastfeeding problems after acquiring breastfeeding counseling as an conclusion, implementation of breastfeeding counseling in the City of Jambi is still less than optimal, seen from the input components is still inadequate, activity components are not yet optimal, while the outputs and outcomes components not achieving the expected

STABILITY OF OMEGA-3 COMPOUNDS COMPLEX WITH PPAR-γ RECEPTOR AS AN ANTI-OBESITY USING MOLECULAR DYNAMIC SIMULATION

Objective: Obesity is a major contributor to comorbid diseases based on low grade chronic inflammation. Omega-3 fatty acids have a role in inflammation so it is thought to prevent obesity. This study was conducted to analyze the stability of omega-3 fatty acids with the PPAR-γ receptor using molecular dynamic simulation to investigate the relationship of macromolecule interactions to biologically relevant as an obesity comorbid. Methods: The methods consisted of ligand acquisition, molecular dynamic simulation, and analysis of dynamic molecular results using Gromacs 2016.3 software and the results of the MD analysis were carried out by simulating time with VMD software and graphing the results of MD data analysis using Microsoft Excel. Results: The result showed that docosahexaenoic acid (DHA), docosapentaenoic acid (DPA), and heneicosapentaenoic acid (HPA) have good stability. Average RMSD values of DHA, DPA, and HPA were 0.347 Å, 0.464 Å, and 0.706 Å with similar pattern of fluctuation across the region. DHA forms a hydrogen bond to Tyr347 and Leu343. Meanwhile, DPA binds to Asn52 and HPA bind to Arg213. DHA, DPA, and HPA have an average SASA of 233.91 nm2, 231.47 nm2, and 225.52 nm2, respectively. DHA has the lowest total binding energy (-129.914 kJ/mol) compared to DPA (-102.018 kJ/mol) and HPA (-115.992 kJ/mol). Conclusion: Based on the molecular dynamics simulation approach, omega-3 compounds, DHA, DPA, and HPA showed that DHA has good stability compared to DPA and HPA. DHA, DPA, and HPA can be used as lead drugs to bind to PPAR-γ receptors to prevent and treat obesity

Pengaruh Pursed Lips Breathing (PLB) Terhadap Nilai Forced Expiratory Volume In One Second (FEV1) Pada Penderita Penyakit Paru Obstruksi Kronis Di Rs Paru Dr Ario Wirawan Salatiga

Introduction: Chronic Pulmonary Obstruction is kinds of chronic pulmonary disorder which commonly appear from the limit of oxygen flow to the lungs and not completely reversible, it is progresif, and usually happened from pulmonary inflamation processes caused by dangerous gas which give systemic disorder. This disorder can be prevented and cured. The main causes of this disease are smoking, smoke, pollution of fire, and dangerous gas element. Objective: This research is done to find out the relationship of Pursed lips breathing Toward Forced Expiratory Volume of One Second (FEV1) Score for Chronic Pulmonary Obstruction At Pulmonary Hospital Dr Ario Wirawan Salatiga. Method: This research was done by using Quasi Experimental Design with pre test and post test design. The research population of this research was 10 people with 10 people as the sample taken according to inclusion and exclusion. The data taken were not normally distributed, statistical test done by non parametric test. Result: Based on the analysis done by using Wilcoxon Test showed that the value of p ≤ 0, 05 so that Ho is denied dan Ha is accepted. It means that there is a relationship of Pursed Lips Breathing (PLB) Toward Forced Expiratory Volume of One Second (FEV1) Score for Chronic Pulmonary Obstruction at Pulmonary Hospital DR Ario Wirawan Salatiga. It is expected that this research can give additional information to the readers or other researcher, especially Chronic Pulmonary Obstruction Patient

Factors Influencing Private Practitioners to Report Tuberculosis Cases

One of the key elements in tuberculosis (TB) management is a system for recording and reporting, in which every health care provider needs to report every TB case to an authorized primary health center (PHC) to support effective treatment. This study was conducted to investigate the present condition of TB recording and reporting system and evaluate several factors that might influence PP behavior regarding the reporting of TB cases to a PHC in Bandung, Indonesia. Face-to-face interviews with PP and the head of the PHC were performed. Data were coded, categorized, and analyzed statistically by Fischer’s exact test. We found that there were four factors influencing the reporting of TB cases by PP to PHC, including self-awareness, ignorance, lack of time, and poor implementation of recording and reporting system. The level of PP self-awareness was significantly associated with the reporting of TB cases (p<0.05). Private sector involvement, improvement in the recording of treatment follow-up, and the use of electronic based reporting were considered important by participants to construct a well-established recording and reporting system for TB cases. In conclusion, there are still room for improvement in the reporting and recording system of TB cases in PHC. Keywords: recording, reporting, tuberculosis, self-awareness, practitioner

Effect of Eel Biscuit Supplementation on Height of Children with Stunting Aged 36–60 Months: A Pilot Study

Background. Stunting is a major health problem in developing countries. Animal-based supplements can increase the height of children with stunting. This study was aimed at determining the effect of eel biscuit supplementation on increase in the height of children with stunting aged 36–60 months. Methods. A pilot study with pretest-post-test design. The study was conducted in two villages in the Priangan Region, West Java Province, Indonesia. The participants were divided into two groups: intervention group (10 supplemented eel biscuit pieces) and control group (biscuits from the government’s biscuit programme). A total of 56 children aged 36–60 months with the height-for-age z-score of <−2 SD were recruited voluntarily for sampling. Results. The initial height-for-age z-score of the intervention group was −3.45 SD and that of the control group was −3.11 SD. After 3 months of supplemented eel biscuit consumption, the height-for-age z-score of the intervention group changed to −2.52 SD and that of the control group changed to −2.51 SD. The average shift of the height-for-age z-score after 3 months of supplemented eel biscuit consumption was 0.93 SD in the intervention group and 0.6 SD in the control group. There were significant differences in delta and percent increase in the height-for-age z-score between both groups. Conclusions. Consumption of supplemented eel biscuits for 3 months increased the height-for-age z-score of children with stunting aged 36–60 months by 0.93 SD

PPAR-gamma Signaling in Metabolic Homeostasis

BACKGROUND: Peroxisome proliferator-activated receptor (PPAR)-γ, or also known as nuclear receptor subfamily 1 group C member 3 (NR1C3), is a PPAR which serves as master regulator of adipocytes differentiation, and plays an important role in lipid metabolism or adipogenesis. Recent study showed that PPAR-γ is expressed in most tissue and also has critical impact in many metabolic homeostasis disorders.CONTENT: Dysregulation of PPAR-γ is correlated to the development of obesity, type 2 diabetes, atherosclerosis, cardiovascular disease, acute kidney injury, autoimmune disease, gastrointestinal disease and Alzheimer\u27s disease. Abundant number of new emerging compounds, with in vitro and in vivo effectiveness as natural and synthetic agonists of PPARs, are investigated, developed and used as the treatment of metabolic disorders of glucose and/or lipid and other diseases.SUMMARY: Based on all studies explanation, targeting PPAR-γ is proven to be a good therapeutic method for reducing negative effect of several metabolic homeostasis disorder. Now, many natural and synthetic agonists of PPARs are used as the treatment of metabolic disorders of glucose and/or lipid or another metabolic homeostasis disorder. Such agonists have different properties andspecificities for individual PPARs receptors, different absorption and distribution, and distinctive gene expression profiles, which ultimately lead to different clinicaloutcomes