1,654 research outputs found
A South African review of harmonic emission level assessment as per IEC61000-3-6
Large-scale renewable power producing plants are being integrated into South African networks.
Network operators need to ensure that Renewable Power Plants (RPP) do not negatively affect the
power quality levels of their networks, as harmonics amongst others could become a concern.
IEC 61000-3-6 details a method for allocating voltage harmonic emission limits for distorting loads.
This method works well for the allocation of emission limits; however it does not address the
management of harmonic emissions once a plant is connected to the network. The management of
harmonic emissions requires that network operators measure or quantify the emissions from loads and
generators to determine compliance. Post-connection quantification of harmonic levels and
compliance is a challenge for network operators. The question asked is “How should a network
operator measure/quantify the harmonic emissions of a load/generator to establish compliance with the
calculated limits as per IEC 61000-3-6”.
This paper reviews within a South African context methods of assessing harmonic emission levels and
then evaluates these methods by means of field data. Opportunities for improvement are identified
and operational requirements discussed
Extending the functionalities of shear-driven chromatography nano-channels using high aspect ratio etching
An new injection system is presented for shear-driven chromatography. The device has been fabricated by high aspect ratio etching of silicon. The performance of the injection slit is studied through the aid of computational fluid dynamics, and the first experimental results are presented
Design and implementation of injector/distributor structures for microfabricated non-porous pillar columns for capillary electrochromatography
A previously proposed foil definition is applied in the design of injector/distributor structures for solid microfabricated column structures for capillary electrochromatography. In addition to a typical bifurcated distributor, an optimized design alternative with two different configurations is experimentally evaluated. Optimized designs yielded a flat profile for the injected sample with a maximum of 3% variation from the mean width, while it went up to 18% for the typical bifurcated distributor. The implemented electrokinetic injection approach enabled controlling the volume of the injected sample accurately without sacrificing the compactness of the device design. The width of the injected sample was directly proportional to the injection time, namely 165 and 218 μm base widths were obtained for 0.6 and 0.8 s of feeding, respectively. Reducing the external porosity of the distributor by 85% compared to the typical design, optimized distributors caused a decrease in the mean flow velocity of up to 70%. However, having a flat initial plug shape enabled the separation of a mixture of Coumarin 440, 460, 480 and 540 at 1 mm downstream of the injection point in 80 s, while it was even not possible to detect the C440 signal for a typical bifurcated design
An Exact Algorithm for Side-Chain Placement in Protein Design
Computational protein design aims at constructing novel or improved functions
on the structure of a given protein backbone and has important applications in
the pharmaceutical and biotechnical industry. The underlying combinatorial
side-chain placement problem consists of choosing a side-chain placement for
each residue position such that the resulting overall energy is minimum. The
choice of the side-chain then also determines the amino acid for this position.
Many algorithms for this NP-hard problem have been proposed in the context of
homology modeling, which, however, reach their limits when faced with large
protein design instances.
In this paper, we propose a new exact method for the side-chain placement
problem that works well even for large instance sizes as they appear in protein
design. Our main contribution is a dedicated branch-and-bound algorithm that
combines tight upper and lower bounds resulting from a novel Lagrangian
relaxation approach for side-chain placement. Our experimental results show
that our method outperforms alternative state-of-the art exact approaches and
makes it possible to optimally solve large protein design instances routinely
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