784 research outputs found
Relational interpretation of the wave function and a possible way around Bell's theorem
The famous ``spooky action at a distance'' in the EPR-szenario is shown to be
a local interaction, once entanglement is interpreted as a kind of ``nearest
neighbor'' relation among quantum systems. Furthermore, the wave function
itself is interpreted as encoding the ``nearest neighbor'' relations between a
quantum system and spatial points. This interpretation becomes natural, if we
view space and distance in terms of relations among spatial points. Therefore,
``position'' becomes a purely relational concept. This relational picture leads
to a new perspective onto the quantum mechanical formalism, where many of the
``weird'' aspects, like the particle-wave duality, the non-locality of
entanglement, or the ``mystery'' of the double-slit experiment, disappear.
Furthermore, this picture cirumvents the restrictions set by Bell's
inequalities, i.e., a possible (realistic) hidden variable theory based on
these concepts can be local and at the same time reproduce the results of
quantum mechanics.Comment: Accepted for publication in "International Journal of Theoretical
Physics
Personal and sub-personal: a defence of Dennett's early distinction
Since 1969, when Dennett introduced a distinction between personal and subâpersonal levels of explanation, many philosophers have used âsubâpersonalâ very loosely, and Dennett himself has abandoned a view of the personal level as genuinely autonomous. I recommend a position in which Dennett's original distinction is crucial, by arguing that the phenomenon called mental causation is on view only at the properly personal level. If one retains the commitââ ments incurred by Dennett's early distinction, then one has a satisfactory antiâphysicalistic, antiâdualist philosophy of mind. It neither interferes with the projects of subâpersonal psychology, nor encourages ; instrumentalism at the personal level.
People lose sight of Dennettâs personal/sub-personal distinction because they free it from its philosophical moorings. A distinction that serves a philosophical purpose is typically rooted in doctrine; it cannot be lifted out of context and continue to do its work. So I shall start from Dennettâs distinction as I read it in its original context. And when I speak of âthe distinctionâ, I mean to point not only towards the terms that Dennett first used to define it but also towards the philosophical setting within which its work was cut out
The Network Analysis of Urban Streets: A Primal Approach
The network metaphor in the analysis of urban and territorial cases has a
long tradition especially in transportation/land-use planning and economic
geography. More recently, urban design has brought its contribution by means of
the "space syntax" methodology. All these approaches, though under different
terms like accessibility, proximity, integration,connectivity, cost or effort,
focus on the idea that some places (or streets) are more important than others
because they are more central. The study of centrality in complex
systems,however, originated in other scientific areas, namely in structural
sociology, well before its use in urban studies; moreover, as a structural
property of the system, centrality has never been extensively investigated
metrically in geographic networks as it has been topologically in a wide range
of other relational networks like social, biological or technological. After
two previous works on some structural properties of the dual and primal graph
representations of urban street networks (Porta et al. cond-mat/0411241;
Crucitti et al. physics/0504163), in this paper we provide an in-depth
investigation of centrality in the primal approach as compared to the dual one,
with a special focus on potentials for urban design.Comment: 19 page, 4 figures. Paper related to the paper "The Network Analysis
of Urban Streets: A Dual Approach" cond-mat/041124
Mice lacking AMP-activated protein kinase alpha 1 catalytic subunit have increased bone remodelling and modified skeletal responses to hormonal challenges induced by ovariectomy and intermittent PTH treatment
Bregman Voronoi Diagrams: Properties, Algorithms and Applications
The Voronoi diagram of a finite set of objects is a fundamental geometric
structure that subdivides the embedding space into regions, each region
consisting of the points that are closer to a given object than to the others.
We may define many variants of Voronoi diagrams depending on the class of
objects, the distance functions and the embedding space. In this paper, we
investigate a framework for defining and building Voronoi diagrams for a broad
class of distance functions called Bregman divergences. Bregman divergences
include not only the traditional (squared) Euclidean distance but also various
divergence measures based on entropic functions. Accordingly, Bregman Voronoi
diagrams allow to define information-theoretic Voronoi diagrams in statistical
parametric spaces based on the relative entropy of distributions. We define
several types of Bregman diagrams, establish correspondences between those
diagrams (using the Legendre transformation), and show how to compute them
efficiently. We also introduce extensions of these diagrams, e.g. k-order and
k-bag Bregman Voronoi diagrams, and introduce Bregman triangulations of a set
of points and their connexion with Bregman Voronoi diagrams. We show that these
triangulations capture many of the properties of the celebrated Delaunay
triangulation. Finally, we give some applications of Bregman Voronoi diagrams
which are of interest in the context of computational geometry and machine
learning.Comment: Extend the proceedings abstract of SODA 2007 (46 pages, 15 figures
Looking backward: From Euler to Riemann
We survey the main ideas in the early history of the subjects on which
Riemann worked and that led to some of his most important discoveries. The
subjects discussed include the theory of functions of a complex variable,
elliptic and Abelian integrals, the hypergeometric series, the zeta function,
topology, differential geometry, integration, and the notion of space. We shall
see that among Riemann's predecessors in all these fields, one name occupies a
prominent place, this is Leonhard Euler. The final version of this paper will
appear in the book \emph{From Riemann to differential geometry and relativity}
(L. Ji, A. Papadopoulos and S. Yamada, ed.) Berlin: Springer, 2017
Effect of surface topography with different groove angles on tribological behavior of the wheel/rail contact using alternative machine
The fables of pity: Rousseau, Mandeville and the animal-fable
Copyright @ 2012 Edinburgh University PressPrompted by Derridaâs work on the animal-fable in eighteenth-century debates about political power, this article examines the role played by the fiction of the animal in thinking of pity as either a natural virtue (in Rousseauâs Second Discourse) or as a natural passion (in Mandevilleâs The Fable of the Bees). The war of fables between Rousseau and Mandeville â and their hostile reception by Samuel Johnson and Adam Smith â reinforce that the animal-fable illustrates not so much the proper of man as the possibilities and limitations of a moral philosophy that is unable to address the political realities of the state
Mild orotic aciduria in UMPS heterozygotes: a metabolic finding without clinical consequences
BACKGROUND: Elevated urinary excretion of orotic acid is associated with treatable disorders of the urea cycle and pyrimidine metabolism. Establishing the correct and timely diagnosis in a patient with orotic aciduria is key to effective treatment. Uridine monophosphate synthase is involved in de novo pyrimidine synthesis. Uridine monophosphate synthase deficiency (or hereditary orotic aciduria), due to biallelic mutations in UMPS, is a rare condition presenting with megaloblastic anemia in the first months of life. If not treated with the pyrimidine precursor uridine, neutropenia, failure to thrive, growth retardation, developmental delay, and intellectual disability may ensue. METHODS AND RESULTS: We identified mild and isolated orotic aciduria in 11 unrelated individuals with diverse clinical signs and symptoms, the most common denominator being intellectual disability/developmental delay. Of note, none had blood count abnormalities, relevant hyperammonemia or altered plasma amino acid profile. All individuals were found to have heterozygous alterations in UMPS. Four of these variants were predicted to be null alleles with complete loss of function. The remaining variants were missense changes and predicted to be damaging to the normal encoded protein. Interestingly, family screening revealed heterozygous UMPS variants in combination with mild orotic aciduria in 19 clinically asymptomatic family members. CONCLUSIONS: We therefore conclude that heterozygous UMPS-mutations can lead to mild and isolated orotic aciduria without clinical consequence. Partial UMPS-deficiency should be included in the differential diagnosis of mild orotic aciduria. The discovery of heterozygotes manifesting clinical symptoms such as hypotonia and developmental delay are likely due to ascertainment bias
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