Shock Geometry and Spectral Breaks in Large SEP Events

Solar energetic particle (SEP) events are traditionally classified as "impulsive" or "gradual." It is now widely accepted that in gradual SEP events, particles are accelerated at coronal mass ejection-driven (CME-driven) shocks. In many of these large SEP events, particle spectra exhibit double power law or exponential rollover features, with the break energy or rollover energy ordered as (Q/A)^α, with Q being the ion charge in e and A the ion mass in units of proton mass m_p . This Q/A dependence of the spectral breaks provides an opportunity to study the underlying acceleration mechanism. In this paper, we examine how the Q/A dependence may depend on shock geometry. Using the nonlinear guiding center theory, we show that α ~ 1/5 for a quasi-perpendicular shock. Such a weak Q/A dependence is in contrast to the quasi-parallel shock case where α can reach 2. This difference in α reflects the difference of the underlying parallel and perpendicular diffusion coefficients κ_(||) and κ ⊥. We also examine the Q/A dependence of the break energy for the most general oblique shock case. Our analysis offers a possible way to remotely examine the geometry of a CME-driven shock when it is close to the Sun, where the acceleration of particle to high energies occurs

Isolated bilateral simplex ureteric ectopia: Bladder capacity as an indicator of continence outcome

INTRODUCTION: Isolated bilateral simplex ectopic ureters (BSEUs) are rare but pose a therapeutic challenge: ureteric reimplantation alone does not accomplish continence in all. Identifying the patients needing additional procedures for continence early could prevent multiple operations. OBJECTIVE: Potential preoperative indicators for postoperative continence are explored in eight BSEU girls without cloacal, anorectal, or spinal anomalies. STUDY DESIGN: With institutional approval, all patients with BSEU between 1985 and 2012 were retrospectively reviewed. Cystoscopy determined the site of ureteric ectopia (6 of 16 at the bladder neck [BN], 5 of 16 below the BN, and 5 of 16 in the distal urethra). Bladders were assessed by a combination of ultrasound, urodynamics, micturating cystourethrogram, cystoscopic, and intraoperative observations. Expected bladder capacity for age (EBCA) was calculated by 30 ml + (30 ml × age in years) or 38 ml + (2.5 ml × age in months) for children greater or less than 2 years, respectively. Continence outcomes were appraised at a minimum of 4 years. The small number of patients precludes credible statistical analysis and therefore raw data are presented. RESULTS: Patients underwent cross-trigonal ureteric reimplantation at 1–5.5 years, in five without BN surgery and in three with a Young–Dees–Leadbetter BN tightening. Of those without BN surgery at reimplantation, four achieved satisfactory continence for their age, but one has had multiple procedures culminating in BN closure, ileocystoplasty, and Mitrofanoff. Among the BN-tightening group, one was in nappies at 4 years, one had residual stress incontinence after two further BN injections, and one proceeded to artificial urinary sphincter after two BN injections. Five patients had significant renal impairment. DISCUSSION: Patients with satisfactory continence after reimplantation alone and those needing further procedures tended to differ in their preoperative observations of bladder capacity and apparent BN competence. This study suggests preoperative observations of an empty bladder on serial ultrasound and/or a wide-open BN with small or even moderate bladder capacity at cystoscopy to indicate the need for BN surgery. In contrast, children with bladder filling to at least 30% of expected bladder capacity for age on preoperative ultrasound or apposition of the BN at cystoscopy may achieve satisfactory continence after ureteric reimplantation alone. Bladder capacity as an indicator of BN competence can also be correlated to continence outcomes in previously published series. Polyuria associated with renal impairment can exacerbate the challenge for continence. CONCLUSION: Preoperative bladder capacity appears to be an indicator of inherent BN function and a thorough assessment of the urinary tract by cystoscopy, ultrasound, micturating cystourethrogram, and functional imaging may guide the surgeon on the need for BN surgery at the time of ureteric reimplantation. Where continence remains elusive, patients should be counselled that a further BN injection is occasionally of value although more significant BN procedures are required for most

Science Validation of the Spitzer Source List

The Spitzer Science Center will produce a source list (SL) of photometry for a large subset of imaging data in the Spitzer Heritage Archive (SHA). The list will enable a large range of science projects. The primary requirement on the SL is very high reliability — with areal coverage, completeness and limiting depth being secondary considerations. The SHA at the NASA Infrared Science Archive (IRSA) will serve the SL as an enhanced data product. The SL will include data from the four channels of IRAC (3–8 microns) and the 24 micron channel of MIPS. The Source List will include image products (mosaics) and photometric data for Spitzer observations of about 1500 square degrees and include around 30 million sources. We describe ongoing science validation of the Spitzer Source List, and discuss the range of use cases which will be supported

Surface roughness effect on ultracold neutron interaction with a wall and implications for computer simulations

We review the diffuse scattering and the loss coefficient in ultracold neutron reflection from slightly rough surfaces, report a surprising reduction in loss coefficient due to roughness, and discuss the possibility of transition from quantum treatment to ray optics. The results are used in a computer simulation of neutron storage in a recent neutron lifetime experiment that re-ported a large discrepancy of neutron lifetime with the current particle data value. Our partial re-analysis suggests the possibility of systematic effects that were not included in this publication.Comment: 39 pages, 9 figures; additional calculations include

A New Simulation Metric to Determine Safe Environments and Controllers for Systems with Unknown Dynamics

We consider the problem of extracting safe environments and controllers for reach-avoid objectives for systems with known state and control spaces, but unknown dynamics. In a given environment, a common approach is to synthesize a controller from an abstraction or a model of the system (potentially learned from data). However, in many situations, the relationship between the dynamics of the model and the \textit{actual system} is not known; and hence it is difficult to provide safety guarantees for the system. In such cases, the Standard Simulation Metric (SSM), defined as the worst-case norm distance between the model and the system output trajectories, can be used to modify a reach-avoid specification for the system into a more stringent specification for the abstraction. Nevertheless, the obtained distance, and hence the modified specification, can be quite conservative. This limits the set of environments for which a safe controller can be obtained. We propose SPEC, a specification-centric simulation metric, which overcomes these limitations by computing the distance using only the trajectories that violate the specification for the system. We show that modifying a reach-avoid specification with SPEC allows us to synthesize a safe controller for a larger set of environments compared to SSM. We also propose a probabilistic method to compute SPEC for a general class of systems. Case studies using simulators for quadrotors and autonomous cars illustrate the advantages of the proposed metric for determining safe environment sets and controllers.Comment: 22nd ACM International Conference on Hybrid Systems: Computation and Control (2019

Prognosis of operable squamous cell carcinoma of the esophagus. Relationship with clinicopathologic features and DNA ploidy

Background: Reports on the influence of various prognostic factors in carcinoma of the esophagus are conflicting. The prognostic value of a set of clinicopathologic factors and DNA ploidy were examined in 74 patients with surgically resected squamous cell carcinoma of the lower and middle third of the esophagus. Methods: All patients had surgery performed in a single thoracic surgical unit at the Tata Memorial Hospital between January, 1984 and December, 1987. The clinicopathologic factors studied were (1) gross residual disease at operation; (2) morphology of the tumor; (3) depth of microscopic invasion; (4) lymph node involvement; (5) histologic grade; (6) vascular and lymphatic embolism; and (7) sex. DNA ploidy and S-phase fraction (SpF) were determined by flow cytometry on archival tissues extracted from paraffin blocks. Ploidy status could be determined successfully in all 74 tumors, whereas SpF could be assessed only in 25. Results: Of the various prognostic factors examined with the Cox stepwise regression model, residual disease (P = 0.000), depth of invasion (P = 0.047), and lymph node status (P = 0.077) were found to be correlated with overall survival. Conclusions: DNA ploidy was not related to prognosis. The overall survival of this group of patients at 36 months was 28%, and median survival was 18 months

Availability and Utilization of Malaria Prevention Strategies in Pregnancy in Eastern India

BACKGROUND. Malaria in pregnancy in India, as elsewhere, is responsible for maternal anemia and adverse pregnancy outcomes such as low birth weight and preterm birth. It is not known whether prevention and treatment strategies for malaria in pregnancy (case management, insecticide-treated bednets, intermittent preventive therapy) are widely utilized in India. METHODS. This cross-sectional study was conducted during 2006-2008 in two states of India, Jharkhand and Chhattisgarh, at 7 facilities representing a range of rural and urban populations and areas of more versus less stable malaria transmission. 280 antenatal visits (40/site) were observed by study personnel coupled with exit interviews of pregnant women to assess emphasis upon, availability and utilization of malaria prevention practices by health workers and pregnant women. The facilities were assessed for the availability of antimalarials, lab supplies and bednets. RESULTS. All participating facilities were equipped to perform malaria blood smears; none used rapid diagnostic tests. Chloroquine, endorsed for chemoprophylaxis during pregnancy by the government at the time of the study, was stocked regularly at all facilities although the quantity stocked varied. Availability of alternative antimalarials for use in pregnancy was less consistent. In Jharkhand, no health worker recommended bednet use during the antenatal visit yet over 90% of pregnant women had bednets in their household. In Chhattisgarh, bednets were available at all facilities but only 14.4% of health workers recommended their use. 40% of the pregnant women interviewed had bednets in their household. Only 1.4% of all households owned an insecticide-treated bednet; yet 40% of all women reported their households had been sprayed with insecticide. Antimalarial chemoprophylaxis with chloroquine was prescribed in only 2 (0.7%) and intermittent preventive therapy prescribed in only one (0.4%) of the 280 observed visits. CONCLUSIONS. A disconnect remains between routine antenatal practices in India and known strategies to prevent and treat malaria in pregnancy. Prevention strategies, in particular the use of insecticide-treated bednets, are underutilized. Gaps highlighted by this study combined with recent estimates of the prevalence of malaria during pregnancy in these areas should be used to revise governmental policy and target increased educational efforts among health care workers and pregnant women.United States Agency for International Development/India mission (cooperative agreement GHS-A-00-03-00020-00); National Institute of Allergy and Infectious Disease (R03 HD52167-01); Indian National Institute of Malaria Research; Indo-US Program for Contraception and Reproductive Health Researc

Abundances and energy spectra of corotating interaction region heavy ions

We have surveyed He-Fe spectra for 41 Corotating Interaction Regions (CIRs) from 1998–2007 observed on ACE. The spectra are similar for all species, and have the form of broken power laws with the spectral break occurring at a few MeV/nucleon. Except for overabundances of He and Ne, the abundances are close to those of the solar wind. We find the rare isotope ^3He is enhanced in ~40% of the events. In individual CIRs the Fe/O ratio correlates strongly with the solar wind Fe/O ratio measured 2–4 days prior to the CIR passage. Taken together with previously reported observations of pick-up He^+ in CIRs, these observations provide evidence that CIRs are accelerated out of a suprathermal ion pool of heated solar wind ions, pick-up ions, and remnant suprathermal ions from impulsive solar energetic particle (SEP) events

The AGN Contribution to the Mid-IR Emission of Luminous Infrared Galaxies

We determine the contribution of AGN to the mid-IR emission of luminous infrared galaxies (LIRGs) at z>0.6 by measuring the mid-IR dust continuum slope of 20,039 mid-IR sources. The 24 micron sources are selected from a Spitzer/MIPS survey of the NOAO Deep Wide-Field Survey Bo\"otes field and have corresponding 8 micron data from the IRAC Shallow Survey. There is a clear bimodal distribution in the 24 micron to 8 micron flux ratio. The X-ray detected sources fall within the peak corresponding to a flat spectrum in nufnu, implying that it is populated by AGN-dominated LIRGs, whereas the peak corresponding to a higher 24 micron to 8 micron flux ratio is likely due to LIRGs whose infrared emission is powered by starbursts. The 24 micron emission is increasingly dominated by AGN at higher 24 micron flux densities (f_24): the AGN fraction of the z>0.6 sources increases from ~9% at f_24 ~ 0.35 mJy to 74+/-20% at f_24 ~ 3 mJy in good agreement with model predictions. Deep 24 micron, small area surveys, like GOODS, will be strongly dominated by starburst galaxies. AGN are responsible for ~ 3-7% of the total 24 micron background.Comment: 6 pages, accepted for publication in Ap

HST Morphologies of z~2 Dust Obscured Galaxies I: Power-law Sources

We present high spatial resolution optical and near-infrared imaging obtained using the ACS, WFPC2 and NICMOS cameras aboard the Hubble Space Telescope of 31 24um--bright z~2 Dust Obscured Galaxies (DOGs) identified in the Bootes Field of the NOAO Deep Wide-Field Survey. Although this subset of DOGs have mid-IR spectral energy distributions dominated by a power-law component suggestive of an AGN, all but one of the galaxies are spatially extended and not dominated by an unresolved component at rest-frame UV or optical wavelengths. The observed V-H and I-H colors of the extended components are 0.2-3 magnitudes redder than normal star-forming galaxies. All but 1 have axial ratios >0.3, making it unlikely that DOGs are composed of an edge-on star-forming disk. We model the spatially extended component of the surface brightness distributions of the DOGs with a Sersic profile and find effective radii of 1-6 kpc. This sample of DOGs is smaller than most sub-millimeter galaxies (SMGs), but larger than quiescent high-redshift galaxies. Non-parametric measures (Gini and M20) of DOG morphologies suggest that these galaxies are more dynamically relaxed than local ULIRGs. We estimate lower limits to the stellar masses of DOGs based on the rest-frame optical photometry and find that these range from ~10^(9-11) M_sun. If major mergers are the progenitors of DOGs, then these observations suggest that DOGs may represent a post-merger evolutionary stage.Comment: 23 pages, 9 figures, 6 tables, accepted to ApJ; lower limits on stellar mass revised upwards by factor of (1+z