59 research outputs found

    High-Frequency Electrooptic Fabry-Perot Modulators

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    Electrooptic modulators built from GaAs/AlxGa1-xAs Fabry-Perot cavities operating up to 6.5 GHz are reported. The measured frequency response agrees well with the one predicted using an equivalent circuit model derived from high-speed electrical measurements. The parasitic capacitances have been reduced to approximately 30 fF by fabricating the devices on semi-insulating GaAs substrates and integrating them with on-wafer bound pads which have dimensions compatible with microwave coplanar probes

    Genome modeling system: A knowledge management platform for genomics

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    In this work, we present the Genome Modeling System (GMS), an analysis information management system capable of executing automated genome analysis pipelines at a massive scale. The GMS framework provides detailed tracking of samples and data coupled with reliable and repeatable analysis pipelines. The GMS also serves as a platform for bioinformatics development, allowing a large team to collaborate on data analysis, or an individual researcher to leverage the work of others effectively within its data management system. Rather than separating ad-hoc analysis from rigorous, reproducible pipelines, the GMS promotes systematic integration between the two. As a demonstration of the GMS, we performed an integrated analysis of whole genome, exome and transcriptome sequencing data from a breast cancer cell line (HCC1395) and matched lymphoblastoid line (HCC1395BL). These data are available for users to test the software, complete tutorials and develop novel GMS pipeline configurations. The GMS is available at https://github.com/genome/gms

    Temperature and Resource Availability May Interactively Affect Over-Wintering Success of Juvenile Fish in a Changing Climate

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    The predicted global warming may affect freshwater systems at several organizational levels, from organism to ecosystem. Specifically, in temperate regions, the projected increase of winter temperatures may have important effects on the over-winter biology of a range of organisms and especially for fish and other ectothermic animals. However, temperature effects on organisms may be directed strongly by resource availability. Here, we investigated whether over-winter loss of biomass and lipid content of juvenile roach (Rutilus rutilus) was affected by the physiologically relatively small (2-5°C) changes of winter temperatures predicted by the Intergovernmental Panel on Climate Change (IPCC), under both natural and experimental conditions. This was investigated in combination with the effects of food availability. Finally, we explored the potential for a correlation between lake temperature and resource levels for planktivorous fish, i.e., zooplankton biomass, during five consecutive winters in a south Swedish lake. We show that small increases in temperature (+2°C) affected fish biomass loss in both presence and absence of food, but negatively and positively respectively. Temperature alone explained only a minor part of the variation when food availability was not taken into account. In contrast to other studies, lipid analyses of experimental fish suggest that critical somatic condition rather than critical lipid content determined starvation induced mortality. Our results illustrate the importance of considering not only changes in temperature when predicting organism response to climate change but also food-web interactions, such as resource availability and predation. However, as exemplified by our finding that zooplankton over-winter biomass in the lake was not related to over-winter temperature, this may not be a straightforward task

    On the use of finite Taylor's series approximations to certain exponential and power functions employed in cloud models

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    April, 1977.Includes bibliographical references.Sponsored by NSF DES 75-13310.Sponsored by NSF ERT-71-01885-A03

    Microwave and Millimeter Wave Signal Generation Using Mode-Locked Semiconductor Lasers with Intra-Waveguide Saturable Absorbers

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    Microwave and millimeter wave signals can be generated using mode-locked semiconductor lasers with intra-waveguide saturable absorbers. Monolithic and external cavity devices optimized for electrical and optical signal generation are discussed along with measurements of amplitude noise, phase noise, output power, and repetition rate tunability

    Repetition Frequency Stabilisation of Passively Mode-Locked Semiconductor Lasers

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    The repetition frequency of an external cavity mode-locked GaAs semiconductor diode laser has been stabilized by voltage controlled electrical feedback. The phase noise has been reduced by 40dB at 1 kHz offset from the carrier and timing jitter reduced from more than 30ps to 4ps. This technique can be used to stabilize millimetre-wave mode-locked lasers

    Transitions in boundary layer meso-convective structures: An observational case study

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    ABSTRACT Boundary layer rolls over Lake Michigan have been observed in wintertime conditions predicted by many past studies to favor nonroll convective structures (such as disorganized convection or cellular convection). This study examines mechanisms that gave rise to transitions between boundary layer rolls and more cellular convective structures observed during a lake-effect snow event over Lake Michigan on 17 December 1983. The purposes of this study are to better understand roll formation in marine boundary layers strongly heated from below and examine the evolution of snowfall rate and mass overturning rate within the boundary layer during periods of convective transition. A method of quantifying the uniformity of convection along the roll axes, based on dual-Doppler radar-derived vertical motions, was developed to quantify changes in boundary layer convective structure. Roll formation was found to occur after (within 1 h) increases in low-level wind speeds and speed shear primarily below about 0.3z i , with little change in directional shear within the convective boundary layer. Roll convective patterns appeared to initiate upstream of the sample region, rather than form locally near the downwind shore of Lake Michigan. These findings suggest that either rolls developed over the upwind half of Lake Michigan or that the convection had a delayed response to changes in the atmospheric surface and wind forcing. Mass overturning rates at midlevels in the boundary layer peaked when rolls were dominant and gradually decreased when cellular convection became more prevalent. Radar-estimated aerial-mean snowfall rates showed little relationship with changes in convective structure. However, when rolls were dominant, the heaviest snow was more concentrated in updraft regions than during more cellular time periods
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