254 research outputs found
Spectroscopy and Time Variability of Absorption Lines in the Direction of the Vela Supernova Remnant
We present high resolution (R~75,000), high signal-to-noise (S/N~100) Ca II
3933.663 and Na I 5889.951, 5895.924 spectra of 68
stars in the direction of the Vela supernova remnant. The spectra comprise the
most complete high resolution, high S/N, optical survey of early type stars in
this region of the sky. A subset of the sight lines has been observed at
multiple epochs, 1993/1994 and 1996. Of the thirteen stars observed twice,
seven have spectra revealing changes in the equivalent width and/or velocity
structure of lines, most of which arise from remnant gas. Such time variability
has been reported previously for the sight lines towards HD 72089 and HD 72997
by Danks & Sembach (1995) and for HD 72127 by Hobbs et al. (1991). We have
confirmed the ongoing time variability of these spectra and present new
evidence of variability in the spectra of HD 73658, HD 74455, HD 75309 and HD
75821. We have tabulated Na I and Ca II absorption line information for the
sight lines in our sample to serve as a benchmark for further investigations of
the dynamics and evolution of the Vela SNR.Comment: 8 pages of text, 4 tables, 16 pages of figures Accepted and to be
published in ApJ
An Analysis of the Shapes of Interstellar Extinction Curves. V. The IR-Through-UV Curve Morphology
We study the IR-through-UV interstellar extinction curves towards 328
Galactic B and late-O stars. We use a new technique which employs stellar
atmosphere models in lieu of unreddened "standard" stars. This technique is
capable of virtually eliminating spectral mismatch errors in the curves. It
also allows a quantitative assessment of the errors and enables a rigorous
testing of the significance of relationships between various curve parameters,
regardless of whether their uncertainties are correlated. Analysis of the
curves gives the following results: (1) In accord with our previous findings,
the central position of the 2175 A extinction bump is mildly variable, its
width is highly variable, and the two variations are unrelated. (2) Strong
correlations are found among some extinction properties within the UV region,
and within the IR region. (3) With the exception of a few curves with extreme
(i.e., large) values of R(V), the UV and IR portions of Galactic extinction
curves are not correlated with each other. (4) The large sightline-to-sightline
variation seen in our sample implies that any average Galactic extinction curve
will always reflect the biases of its parent sample. (5) The use of an average
curve to deredden a spectral energy distribution (SED) will result in
significant errors, and a realistic error budget for the dereddened SED must
include the observed variance of Galactic curves. While the observed large
sightline-to-sightline variations, and the lack of correlation among the
various features of the curves, make it difficult to meaningfully characterize
average extinction properties, they demonstrate that extinction curves respond
sensitively to local conditions. Thus, each curve contains potentially unique
information about the grains along its sightline.Comment: To appear in the Astrophysical Journal, Part 1, July 1, 2007. Figures
and Tables which will appear only in the electronic version of the Journal
can be obtained via anonymous ftp from ftp://ftp.astronomy.villanova.edu .
After logging in, change directories to "fitz/FMV_EXTINCTION". A README file
describes the various files present in the director
FUSE Measurements of Far Ultraviolet Extinction. I. Galactic Sight Lines
We present extinction curves that include data down to far ultraviolet
wavelengths (FUV; 1050 - 1200 A) for nine Galactic sight lines. The FUV
extinction was measured using data from the Far Ultraviolet Spectroscopic
Explorer. The sight lines were chosen for their unusual extinction properties
in the infrared through the ultraviolet; that they probe a wide range of dust
environments is evidenced by the large spread in their measured ratios of
total-to-selective extinction, R_V = 2.43 - 3.81. We find that extrapolation of
the Fitzpatrick & Massa relationship from the ultraviolet appears to be a good
predictor of the FUV extinction behavior. We find that predictions of the FUV
extinction based upon the Cardelli, Clayton & Mathis (CCM) dependence on R_V
give mixed results. For the seven extinction curves well represented by CCM in
the infrared through ultraviolet, the FUV extinction is well predicted in three
sight lines, over-predicted in two sight lines, and under-predicted in 2 sight
lines. A Maximum Entropy Method analysis using a simple three component grain
model shows that seven of the nine sight lines in the study require a larger
fraction of grain materials to be in dust when FUV extinction is included in
the models. Most of the added grain material is in the form of small (radii <
200 A) grains.Comment: Accepted for publication in the Astrophysical Journal. 31 pages with
7 figure
Galactic Structure Toward the Carina Tangent
This investigation presents a photometric study of the Galactic structure
toward the Carina arm tangent. The field is located between 280 deg and 286 deg
galactic longitude and -4 deg to 4 deg galactic latitude. All currently
available uvbybeta data is used to obtain homogeneous color excesses and
distances for more than 260 stars of spectral types O to G. We present revised
distances and average extinction for the open clusters and cluster candidates
NGC 3293, NGC 3114, Loden 46 and Loden 112. The cluster candidate Loden 112
appears to be a very compact group at a true distance modulus of 11.06 +\- 0.11
(s.e.) (1629 +84,-80 pc), significantly closer than previous estimates. We
found other OB stars at that same distance and, based on their proper motions,
suggest a new OB association at coordinates 282 deg < l < 285 deg, -2 deg < b <
2 deg. Utilizing BV photometry and spectral classification of the known O-type
stars in the very young open cluster Wd 2 we provide a new distance estimate of
14.13 +\-0.16 (s.e.) (6698 +512,-475 pc), in excellent agreement with recent
distance determinations to the giant molecular structures in this direction. We
also discuss a possible connection between the HII region RCW 45 and the
highly-reddened B+ star CPD -55 3036 and provide a revised distance for the
luminous blue variable HR Car.Comment: accepted to PAS
pp60c-src is a positive regulator of growth factor-induced cell scattering in a rat bladder carcinoma cell line.
Enrichment and characterization of thymus-repopulating cells in stroma-dependent cultures of rat bone marrow
The bone marrow precursor cells seeding the thymus have been difficult to investigate using fresh bone marrow and in vivo thymus reconstitution assays. We have therefore designed a short-term bone marrow culture system allowing the study of thymus-repopulating cells in the marrow microenvironment. Low-density rat bone marrow cells were grown on pre-established mouse bone marrow stromal cell layers. Cocultured cells were maintained either under steroid-free conditions (Whitlock/Witte-type culture) or in the presence of 10(-7) M hydrocortisone (Dexter-type culture). After 3 days in vitro, the unanchored cell fractions were tested for their ability to colonize and repopulate fetal mouse thymic lobes in vitro. Both fresh low-density cells and Whitlock/Witte-type cultures, but not Dexter-type cultures, gave rise intrathymically to significant numbers of rat donor-type Thy-1.1high CD2+ CD5low CD43+ cells accounting for 50% to 90% of the organ-cultured cells at day 14. Repopulation of fetal mouse thymic lobes by rat Thy-1.1high cells could be used as a readout assay for initiation of thymopoiesis from bone marrow precursor cells, since 90% of the cells were CD3-/low and TCRalphabeta-/low and 15% of the cells co-expressed CD4 and CD8. Dose-response analysis showed that thymus repopulating cells were at least maintained, if not amplified during the 3-day culture period, leading to at least a 10-fold enrichment as compared to unfractionated bone marrow. Unlike fresh low-density cells before culture, short-term Whitlock/Witte-type cultures were depleted in myeloid-restricted precursor cells. In culture, the thymus-repopulating activity was predominantly associated with a 10% lymphoid cell subset which did not express the B-lineage-associated antigens revealed by HIS24 (the rat B220 equivalent) and HIS50 mAbs. We propose that unanchored thymus-repopulating cells enriched in Whitlock/Witte-type cultures may represent lymphoid-restricted, T-cell precursors of the bone marrow capable of emigrating and colonizing the thymus
UBVI and Ha Photometry of the h & chi Persei cluster
UBVI and Ha photometry is presented for 17319 stars in vicinity of the young
double cluster h & chi Persei. Our photometry extends over a 37arcmin x 1arcdeg
field centered on the association. We construct reddening contours within the
imaged field. We find that the two clusters share a common distance modulus of
11.750.05 and ages of log age(yr) = 7.10.1. From the V-Ha colour, a
measure of the Ha emission strength, we conduct a survey for emission line
objects within the association. We detect a sample of 33 Be stars, 8 of which
are new detections. We present a scenario of evolutionary enhancement of the Be
phenomenon to account for the peak in Be fraction towards the top of the
main-sequence in the population of h & chi Persei and similar young clusters.Comment: 20 pages, 9 figures, AJ Jul
VarGoats project: a dataset of 1159 whole-genome sequences to dissect Capra hircus global diversity
Background: Since their domestication 10,500 years ago, goat populations with distinctive genetic backgrounds have adapted to a broad variety of environments and breeding conditions. The VarGoats project is an international 1000-genome resequencing program designed to understand the consequences of domestication and breeding on the genetic diversity of domestic goats and to elucidate how speciation and hybridization have modeled the genomes of a set of species representative of the genus Capra. Findings: A dataset comprising 652 sequenced goats and 507 public goat sequences, including 35 animals representing eight wild species, has been collected worldwide. We identified 74,274,427 single nucleotide polymorphisms (SNPs) and 13,607,850 insertion-deletions (InDels) by aligning these sequences to the latest version of the goat reference genome (ARS1). A Neighbor-joining tree based on Reynolds genetic distances showed that goats from Africa, Asia and Europe tend to group into independent clusters. Because goat breeds from Oceania and Caribbean (Creole) all derive from imported animals, they are distributed along the tree according to their ancestral geographic origin. Conclusions: We report on an unprecedented international effort to characterize the genome-wide diversity of domestic goats. This large range of sequenced individuals represents a unique opportunity to ascertain how the demographic and selection processes associated with post-domestication history have shaped the diversity of this species. Data generated for the project will also be extremely useful to identify deleterious mutations and polymorphisms with causal effects on complex traits, and thus will contribute to new knowledge that could be used in genomic prediction and genome-wide association studies
Atomic super-resolution tomography
We consider the problem of reconstructing a nanocrystal at atomic resolution from electron microscopy images taken at a few tilt angles. A popular reconstruction approach called discrete tomography confines the atom locations to a coarse spatial grid, which is inspired by the physical a priori knowledge that atoms in a crystalline solid tend to form regular lattices. Although this constraint has proven to be powerful for solving this very under-determined inverse problem in many cases, its key limitation is that, in practice, defects may occur that cause atoms to deviate from regular lattice positions. Here we propose a grid-free discrete tomography algorithm that allows for continuous deviations of the atom locations similar to super-resolution approaches for microscopy. The new formulation allows us to define atomic interaction potentials explicitly, which results in a both meaningful and powerful incorporation of the available physical a priori knowledge about the crystal's properties. In computational experiments, we compare the proposed grid-free method to established grid-based approaches and show that our approach can indeed recover the atom positions more accurately for common lattice defects
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