Impacts of Real-Time Transit Information on Bus Passengers’ Travel Choices Based on Travel Behaviour Survey

Real-time transit information (RTI) service can provide travellers with information on public transport and guide them to arrange departure time and travel mode accordingly. This paper aims to analyse travellers’ choices under RTI by exploring the relationship between the related variables of RTI and passengers’ travel choice. Based on the stated preference (SP) survey data, the ordinal logistic regression model is established to analyse the changing probability of passengers’ travel behaviour under RTI. The model calculation results show that travellers getting off work are more likely to change their travel choice under RTI. When data from the control and experimental groups are compared, the differences in route selection are significant. Specifically, passengers with RTI have a more complex route selection than those without, including their changes of travel mode, departure time, vehicles, and stop choices. The research findings can provide insights into the optimisation of intelligent transit information systems and the strategy of RTI. Also, the analysis of passengers’ travel choice under RTI in the transit network can help to improve network planning

Handling Attrition in Longitudinal Studies: The Case for Refreshment Samples

Panel studies typically suffer from attrition, which reduces sample size and can result in biased inferences. It is impossible to know whether or not the attrition causes bias from the observed panel data alone. Refreshment samples - new, randomly sampled respondents given the questionnaire at the same time as a subsequent wave of the panel - offer information that can be used to diagnose and adjust for bias due to attrition. We review and bolster the case for the use of refreshment samples in panel studies. We include examples of both a fully Bayesian approach for analyzing the concatenated panel and refreshment data, and a multiple imputation approach for analyzing only the original panel. For the latter, we document a positive bias in the usual multiple imputation variance estimator. We present models appropriate for three waves and two refreshment samples, including nonterminal attrition. We illustrate the three-wave analysis using the 2007-2008 Associated Press-Yahoo! News Election Poll.Comment: Published in at http://dx.doi.org/10.1214/13-STS414 the Statistical Science (http://www.imstat.org/sts/) by the Institute of Mathematical Statistics (http://www.imstat.org

PhysarumSpreader: a new bio-Inspired methodology for identifying influential spreaders in complex networks

Identifying influential spreaders in networks, which contributes to optimizing the use of available resources and efficient spreading of information, is of great theoretical significance and practical value. A random-walk-based algorithm LeaderRank has been shown as an effective and efficient method in recognizing leaders in social network, which even outperforms the well-known PageRank method. As LeaderRank is initially developed for binary directed networks, further extensions should be studied in weighted networks. In this paper, a generalized algorithm PhysarumSpreader is proposed by combining LeaderRank with a positive feedback mechanism inspired from an amoeboid organism called Physarum Polycephalum. By taking edge weights into consideration and adding the positive feedback mechanism, PhysarumSpreader is applicable in both directed and undirected networks with weights. By taking two real networks for examples, the effectiveness of the proposed method is demonstrated by comparing with other standard centrality measures

Fan-Shaped Model for Generating the Anisotropic Catchment Area of Subway Stations based on Feeder Taxi Trips

The catchment areas of subway stations have always been considered as a circular shape in previous research. Although some studies show the catchment area may be affected by road conditions, public transportation, land use, and other factors, few studies have discussed the shape of the catchment area. This study focuses on analyzing the anisotropy of catchment areas and developing a sound methodology to generate them. Based on taxi global positioning system (GPS) data, this paper first proposes a data mining method to identify feeder taxi trips around subway stations. Then, a fan-shaped model is proposed and applied to Xi\u27an Metro Line 1 to generate catchment areas. The number and angle of fan areas are determined according to the spatial distribution characteristics of GPS points. Results show that the acceptable distance of the catchment area has significant differences in different directions. The average maximum acceptable distance of one station is 2.31 times the minimum. Furthermore, for feeder taxis, the overlap ratio of the catchment area is very high. Travelers in several places could choose several different stations during the travel. A multiple linear regression model was introduced to find the influencing factors, and the result shows the anisotropy of the catchment area is affected not only by neighboring subway stations, but also by the road network, distance from the city center, and so on

Acceptable Threshold of Parking Charges for Urban Electric Bicycles

Electric bicycles are one of the essential traffic modes in many cities in China. Due to the consideration on safety and efficiency of the urban transportation systems, it is recognized that the use of electric bicycles should be limited by shifting the demand towards public transit by imposing parking charges on electric bicycles. To plan for this, the travellers’ acceptance of parking charges must be taken into account. This paper proposes an acceptable threshold Logit model based on the non-compensation theory to calculate the threshold of the parking charge of electric bicycles. Electric bicycle trips are categorized into seven groups in terms of travel distances. The parking charges are of four discrete levels, from 0, 1, 2 to 3 yuan. Based on the survey data in the city of Handan, the traditional and acceptable threshold Nest-Logit models with the distance intervals and charges have been established and calibrated. Model calibration results show that the acceptable threshold Nest-Logit model is more accurate than the traditional Nest-Logit model, and the parking charge thresholds do exist. Specifically, within 3 km and outside 3 km the parking charge threshold is 1 yuan and 2 yuan, respectively. The parking charge thresholds can help in decision-making for parking pricing of electric bicycles.</p

An improved physarum centrality measure for weighted networks

Identification of the most central node within a network is one of the primary problems in network analysis. Among various centrality measures for weighted networks, most are based on the assumption that information only spreads through the shortest paths. Then, a mathematical model of an amoeboid organism has been used by Physarum centrality to relax the assumption. However, its computational complexity is relatively high by finding competing paths between all pairs of nodes in networks. In this paper, with the idea of a ground node, an improved Physarum centrality is proposed by maintaining the feature of original measure with the performance is greatly enhanced. Examples and applications are given to show the efficiency and effectiveness of our proposed measure in weighted networks.<br /

Dub3 Inhibition Suppresses Breast Cancer Invasion and Metastasis by Promoting Snail1 Degradation

Snail1, a key transcription factor of epithelial–mesenchymal transition (EMT), is subjected to ubiquitination and degradation, but the mechanism by which Snail1 is stabilized in tumours remains unclear. We identify Dub3 as a bona fide Snail1 deubiquitinase, which interacts with and stabilizes Snail1. Dub3 is overexpressed in breast cancer; knockdown of Dub3 resulted in Snail1 destabilization, suppressed EMT and decreased tumour cell migration, invasion, and metastasis. These effects are rescued by ectopic Snail1 expression. IL-6 also stabilizes Snail1 by inducing Dub3 expression, the specific inhibitor WP1130 binds to Dub3 and inhibits the Dub3-mediating Snail1 stabilization in vitroand in vivo. Our study reveals a critical Dub3–Snail1 signalling axis in EMT and metastasis, and provides an effective therapeutic approach against breast cancer

Associations of Educational Attainment, Occupation, Social Class and Major Depressive Disorder among Han Chinese Women

Background The prevalence of major depressive disorder (MDD) is higher in those with low levels of educational attainment, the unemployed and those with low social status. However the extent to which these factors cause MDD is unclear. Most of the available data comes from studies in developed countries, and these findings may not extrapolate to developing countries. Examining the relationship between MDD and socio economic status in China is likely to add to the debate because of the radical economic and social changes occurring in China over the last 30 years. Principal findings We report results from 3,639 Chinese women with recurrent MDD and 3,800 controls. Highly significant odds ratios (ORs) were observed between MDD and full time employment (OR = 0.36, 95% CI = 0.25–0.46, logP = 78), social status (OR = 0.83, 95% CI = 0.77–0.87, logP = 13.3) and education attainment (OR = 0.90, 95% CI = 0.86–0.90, logP = 6.8). We found a monotonic relationship between increasing age and increasing levels of educational attainment. Those with only primary school education have significantly more episodes of MDD (mean 6.5, P-value = 0.009) and have a clinically more severe disorder, while those with higher educational attainment are likely to manifest more comorbid anxiety disorders. Conclusions In China lower socioeconomic position is associated with increased rates of MDD, as it is elsewhere in the world. Significantly more episodes of MDD occur among those with lower educational attainment (rather than longer episodes of disease), consistent with the hypothesis that the lower socioeconomic position increases the likelihood of developing MDD. The phenomenology of MDD varies according to the degree of educational attainment: higher educational attainment not only appears to protect against MDD but alters its presentation, to a more anxious phenotype

Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

A person's lipid profile is influenced by genetic variants and alcohol consumption, but the contribution of interactions between these exposures has not been studied. We therefore incorporated gene-alcohol interactions into a multiancestry genome-wide association study of levels of high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and triglycerides. We included 45 studies in stage 1 (genome-wide discovery) and 66 studies in stage 2 (focused follow-up), for a total of 394,584 individuals from 5 ancestry groups. Analyses covered the period July 2014-November 2017. Genetic main effects and interaction effects were jointly assessed by means of a 2-degrees-of-freedom (df) test, and a 1-df test was used to assess the interaction effects alone. Variants at 495 loci were at least suggestively associated (P <1 x 10(-6)) with lipid levels in stage 1 and were evaluated in stage 2, followed by combined analyses of stage 1 and stage 2. In the combined analysis of stages 1 and 2, a total of 147 independent loci were associated with lipid levels at P <5 x 10(-8) using 2-df tests, of which 18 were novel. No genome-wide-significant associations were found testing the interaction effect alone. The novel loci included several genes (proprotein convertase subtilisin/kexin type 5 (PCSK5), vascular endothelial growth factor B (VEGFB), and apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (APOBEC1) complementation factor (A1CF)) that have a putative role in lipid metabolism on the basis of existing evidence from cellular and experimental models.Peer reviewe

<i>G</i>² Hermite Interpolation by Segmented Spirals

A curve with single-signed, monotonically increasing or decreasing curvatures is referred to as a planar spiral. G2 Hermite data are spiral G2 Hermite data for which only interpolation by a spiral is possible. In this study, we design segmented spirals to geometrically interpolate arbitrary C-shaped G2 Hermite data. To separate the data into two or three spiral data sets, we add one or two new points, related tangent vectors and curvatures. We provide different approaches in accordance with the various locations of the external homothetic centers of two end-curvature circles. We then match new data by constructing two or three segmented spirals. We generate at most three piecewise spirals for arbitrary C-shaped data. Furthermore, we illustrate the suggested techniques with several examples