478 research outputs found
Behavior of the Escape Rate Function in Hyperbolic Dynamical Systems
For a fixed initial reference measure, we study the dependence of the escape
rate on the hole for a smooth or piecewise smooth hyperbolic map. First, we
prove the existence and Holder continuity of the escape rate for systems with
small holes admitting Young towers. Then we consider general holes for Anosov
diffeomorphisms, without size or Markovian restrictions. We prove bounds on the
upper and lower escape rates using the notion of pressure on the survivor set
and show that a variational principle holds under generic conditions. However,
we also show that the escape rate function forms a devil's staircase with jumps
along sequences of regular holes and present examples to elucidate some of the
difficulties involved in formulating a general theory.Comment: 21 pages. v2 differs from v1 only by additions to the acknowledgment
Entropy, Lyapunov Exponents and Escape Rates in Open Systems
We study the relation between escape rates and pressure in general dynamical
systems with holes, where pressure is defined to be the difference between
entropy and the sum of positive Lyapunov exponents. Central to the discussion
is the formulation of a class of invariant measures supported on the survivor
set over which we take the supremum to measure the pressure. Upper bounds for
escape rates are proved for general diffeomorphisms of manifolds, possibly with
singularities, for arbitrary holes and natural initial distributions including
Lebesgue and SRB measures. Lower bounds do not hold in such generality, but for
systems admitting Markov tower extensions with spectral gaps, we prove the
equality of the escape rate with the absolute value of the pressure and the
existence of an invariant measure realizing the escape rate, i.e. we prove a
full variational principle. As an application of our results, we prove a
variational principle for the billiard map associated with a planar Lorentz gas
of finite horizon with holes.Comment: 34 pages, 1 figure; This research is partially supported by NSF grant
DMS-080113
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Nonmalignant respiratory disease mortality among woodworkers participating in the American Cancer Society Cancer Prevention Study-II (CPS-II)
Nonmalignant respiratory disease (NMRD) mortality was examined among woodworkers participating in the American Cancer Society’s CPS-II cohort study. During the 6-year prospective follow-up, there were 97 NMRD deaths among 11,541 men reporting employment in wood-related occupations and 1,338 NMRD deaths among 317,424 men reporting no exposure to wood dust or wood-related jobs. Relative risks, adjusted for age and smoking, were calculated using Poisson regression. A small excess of NMRD was observed among woodworkers. However, the relative risk was higher among woodworkers who did not report exposure to wood dust (RR = 1.52, 95% CI = 1.18–1.97) than those who did (RR = 1.27, 95% CI = 0.91–1.77), and no clear trend with duration of exposure was observed. An excess of NMRD was observed among woodworkers reporting exposure to asbestos (RR = 1.59, 95% CI = 0.85–2.96), as well as the small number of woodworkers reporting exposure to formaldehyde (RR = 1.95, 95% CI = 0.63–6.06), but men not reporting exposure to these substances also had an excess risk. Although limited by a short follow-up period and crude indicators of exposure, the strengths of this analysis were the ability to compare woodworkers to a similar, healthy population and to adjust for the effects of smoking. Cohort studies with better exposure information are needed to examine the role of occupational exposures among woodworkers in the etiology of respiratory disease
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Cancer mortality and wood dust exposure among participants in the American Cancer Society Cancer Prevention Study-II (CPS-II).
In 1994, the International Agency for Research on Cancer (IARC) classified wood dust as a human carcinogen, based on very strong evidence of a carcinogenic risk of sino-nasal cancer. Excesses of other cancers, including lung and stomach, have been reported among persons employed in wood industries or occupationally exposed to wood dust, but not as consistently. We investigated such possible associations using the mortality experience of 362,823 men enrolled in the American Cancer Society’s Cancer Prevention Study—II in 1982 and followed up for 6 years. Within this group, 45,399 men (12.5%) reported either employment in a wood-related occupation or exposure to wood dust or both. Among woodworkers, a small but significant excess risk was found for all causes of death (RR 1.17 (95% CI 1.11–1.24)) and for total malignancies (RR 1.17 (1.05–1.30)). Among men who reported exposure to wood dust, there was an elevated risk of total mortality (RR 1.07 (1.03–1.11)), total malignancies (RR 1.08 (1.01—1.15)), and lung cancer (RR 1.17 (1.04–1.31)). Among woodworkers, a significant trend (P = 0.02) of increasing risk of lung cancer with increasing duration of exposure was observed. An unexpected, significantly increased mortality from prostate cancer was observed in both wood-employed and wood-exposed, and a twofold increased risk of fatal brain cancer was seen among the former. Lung cancer mortality was especially high among woodworkers who also reported exposure to asbestos or formaldehyde, and it appears that exposure to these known carcinogens may partly explain the observed increased risks. Excess sino-nasal cancer was not observed, but the number of cases was small
Проблема коррупции в современном обществе
Abstract
Background
Agricultural workers may be exposed to potential carcinogens including pesticides, sensitizing agents and solar radiation. Previous studies indicate increased risks of hematopoietic cancers and decreased risks at other sites, possibly due to differences in lifestyle or risk behaviours. We present findings from CanCHEC (Canadian Census Health and Environment Cohort), the largest national population-based cohort of agricultural workers.
Methods
Statistics Canada created the cohort using deterministic and probabilistic linkage of the 1991 Canadian Long Form Census to National Cancer Registry records for 1992–2010. Self-reported occupations were coded using the Standard Occupational Classification (1991) system. Analyses were restricted to employed persons aged 25–74 years at baseline (N = 2,051,315), with follow-up until December 31, 2010. Hazard ratios (HR) and 95% confidence intervals (CI) were modeled using Cox proportional hazards for all workers in agricultural occupations (n = 70,570; 70.8% male), stratified by sex, and adjusted for age at cohort entry, province of residence, and highest level of education.
Results
A total of 9515 incident cancer cases (7295 in males) occurred in agricultural workers. Among men, increased risks were observed for non-Hodgkin lymphoma (HR = 1.10, 95% CI = 1.00–1.21), prostate (HR = 1.11, 95% CI = 1.06–1.16), melanoma (HR = 1.15, 95% CI = 1.02–1.31), and lip cancer (HR = 2.14, 95% CI = 1.70–2.70). Decreased risks in males were observed for lung, larynx, and liver cancers. Among female agricultural workers there was an increased risk of pancreatic cancer (HR = 1.36, 95% CI = 1.07–1.72). Increased risks of melanoma (HR = 1.79, 95% CI = 1.17–2.73), leukemia (HR = 2.01, 95% CI = 1.24–3.25) and multiple myeloma (HR = 2.25, 95% CI = 1.16–4.37) were observed in a subset of female crop farmers.
Conclusions
Exposure to pesticides may have contributed to increased risks of hematopoietic cancers, while increased risks of lip cancer and melanoma may be attributed to sun exposure. The array of decreased risks suggests reduced smoking and alcohol consumption in this occupational group compared to the general population
Patchwork Gridshells::Using Modularity to Facilitate Prefabrication and Simplify Construction
Patchwork Gridshells::Using Modularity to Facilitate Prefabrication and Simplify Construction
Modern architectural design has seen a shift towards iconic doubly-curved envelopes enclosing large column-free spaces. Gridshells have long been considered an efficient solution to such designs, but their actual use in practice has not spread worldwide. For elastic gridshells, their advantages in terms of substantial material savings can often be overshadowed by the significant challenges associated with their construction. Similarly, for rigid gridshells, the manufacture of a large number of different members and nodal connections is often a barrier to their implementation. This paper proposes an effective way of designing, fabricating and erecting gridshells. The “Patchwork Gridshell” consists of a number of efficient elastic gridshell patches assembled using rigid gridshell frames. It can easily generate a number of different configurations, use a wide range of materials, and allows more architectural expression of practical long-span forms. The benefits of combining the ingenuously simple efficiency of elastic lattices and the power of digital fabrication are demonstrated by digitally rebuilding four alternative configurations of the Japan Pavilion of the Hanover Expo 2000 as a case study. The result is a flexible digital workflow which creates large column-free spaces that are capable of being constructed efficiently by nonspecialist contractors.</p
Escape Rates and Physically Relevant Measures for Billiards with Small Holes
We study the billiard map corresponding to a periodic Lorentz gas in
2-dimensions in the presence of small holes in the table. We allow holes in the
form of open sets away from the scatterers as well as segments on the
boundaries of the scatterers. For a large class of smooth initial
distributions, we establish the existence of a common escape rate and
normalized limiting distribution. This limiting distribution is conditionally
invariant and is the natural analogue of the SRB measure of a closed system.
Finally, we prove that as the size of the hole tends to zero, the limiting
distribution converges to the smooth invariant measure of the billiard map.Comment: 39 pages, 4 figure
Electron multiplication CCD detector technology advancement for the WFIRST-AFTA coronagraph
The WFIRST-AFTA (Wide Field InfraRed Survey Telescope-Astrophysics Focused Telescope Asset) is a NASA space observatory. It will host two major astronomical instruments: a wide-field imager (WFI) to search for dark energy and carry out wide field near infrared (NIR) surveys, and a coronagraph instrument (CGI) to image and spectrally characterize extrasolar planets. In this paper, we discuss the work that has been carried out at JPL in advancing Electron Multiplying CCD (EMCCD) technology to higher flight maturity, with the goal of reaching a NASA technology readiness level of 6 (TRL-6) by early-to-mid 2016. The EMCCD has been baselined for both the coronagraph's imager and integral field spectrograph (IFS) based on its sub-electron noise performance at extremely low flux levels - the regime where the AFTA CGI will operate. We present results from a study that fully characterizes the beginning of life performance of the EMCCD. We also discuss, and present initial results from, a recent radiation test campaign that was designed and carried out to mimic the conditions of the WFIRST-AFTA space environment in an L2 orbit, where we sought to assess the sensor's end of life performance, particularly degradation of its charge transfer efficiency, in addition to other parameters such as dark current, electron multiplication gain, clock induced charge and read noise
Occupational Health and Safety Issues in Ontario Sawmills and Veneer/Plywood Plants: A Pilot Study
A pilot study was conducted within the Ontario sawmill and veneer/plywood manufacturing industry. Information was collected by postal questionnaire and observational walk-through surveys. Industrial hygiene walk-through surveys were conducted at 22 work sites, and measurements for wood dust, noise, and bioaerosol were taken. The aim of the study was to obtain data on the current status regarding health and safety characteristics and an estimate of wood dust, noise, and bioaerosol exposures. The occupational exposure to wood dust and noise are similar to what has been reported in this industry in Canada and elsewhere. Airborne wood dust concentration ranged between 0.001 mg/m3 and 4.87 mg/m3 as total dust and noise exposure ranged between 55 and 117 dB(A). The study indicates the need for a more comprehensive industry-wide study of wood dust, noise, and bioaersols
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