Структурные сдвиги в экономике Красноярского края и их воздействие на сферу потребления

The authors analyze the state of the scope of the consumption of goods and services in the Krasnoyarsk region. Using the method of least squares are designed Keynesian consumption function of the population of the Krasnoyarsk Territor

Neo-industrial base for sustainable development of raw-materials cluster

Today the issues of overcoming the environmental consequences of the negative structural shift of the Russian economy, accelerating the rate of economic growth, reducing the technological and social-and-economic separation from developed countries are becoming strategically in demand for extractive clusters. The need for methodological and theoretical support of the neo-industrialization of the Russian economy raises the urgency of analyzing ways to solve environmental problems, relying on reducing the share of raw materials production in the gross regional product. The emergence of an innovative paradigm raises environmental requirements for industry, raises the priority of interaction institutions between the state, science and business in the process of reducing environmental damage. The leading role is played by the analysis of innovative nature protection activities in extractive clusters and structuring the competitive advantages of the economy, not related to the export of raw materials

FACTORS ANALYSES AND DETERMINATION OF THEIR INFLUENCE ON THE INDICATORS VALUE COMPETITIVENESS OF GOODS EXPORT

Abstract. The pertinence of the issue is because of the impact of fare aggressiveness elements of the Russian Alliance on the elements of remote exchange the development of merchandise outside the traditions region of the EAEU. The presence of such factors won't take into account the compelling usage of state trade approach and the advancement of the national economy. Thusly, it is important to distinguish such factors, their examination, to decide the level of their impact and to shape recommendations for taking measures on their disposal. In such manner, the reason for the article is to recognize the level of impact of fare aggressiveness factors on the fare intensity pointersproclaimed in Russian and worldwide reports. The main strategies for perception fundamental the investigation of this issue are examination, union and enlistment, permitting to distinguish the level of impact of fare intensity factors on fare aggressiveness pointers and to legitimize recommendations for their leveling. The fundamental aftereffect of the article is the development of a grid, which obviously demonstrates the impact of components on individual markers of fare aggressiveness, apportioned by global associations, which will figure out which factors have an increasingly negative effect on the execution of fare intensity in a bigger volume and, hence, should be tended to as a need. Thematerials of the article can be utilized to evaluate the fare aggressiveness of mechanical and different items; will decide further headings to improve the state arrangement in the field of Russian fares' advancement and increment the allure of the residential economy in remote markets.Keywords: export competitiveness, factors of export competitiveness, indicators, state support of export

The influence of raw materials on the biochemical profile of distillates

This study focuses on exploring novel ingredients for the production of safe, high-quality alcoholic beverages and enhancing the processes involved in fermenting beverages. These efforts aim to support local community development initiatives targeting food security, food sovereignty, and small businesses. The article presents the technology for producing distillates from vegetative raw materials, integrating digital technologies for quality control across all manufacturing stages. Distillates were obtained using the “Minispirtzavod Simpl 2018 set “Authentic” equipment, featuring remote control capabilities and a built-in Wi-Fi module. The quality of distillates derived from various vegetable raw materials, including grapes, apples, wheat, and birch sap, was evaluated through organoleptic analysis, assessing appearance, aroma, and taste. Gas chromatography was employed to determine the content of ethyl alcohol, furfural, methyl alcohol, aldehydes, ethers, and fusel alcohol in the distillates. The resulting distillates contained 40.9% to 43.5% vol.% ethanol and exhibited distinct aromatic profiles and flavors based on the vegetative raw material used. This diversity offers opportunities to expand the range of alcoholic products available

COMPREHENSIVE ASSESSMENT OF THE QUALITY AND BIOLOGICAL VALUE OF APPLE FRUIT OF DIFFERENT VARIETIES GROWN IN THE CONDITIONS OF THE REPUBLIC OF ADYGEA

Background. Apple fruits are a valuable food product with a unique chemical composition that determines the taste and biological value. The chemical composition of fruits depends on the variety of apples, ripening terms, conditions and place of growth, which makes research relevant in the conditions of a certain region, including the Republic of Adygea, where horticulture not only has deep historical roots, but has been actively reviving and developing in recent decades. with the use of new technologies and the introduction of new varieties. Target. Carrying out a comprehensive assessment of the quality and biological value of apple fruits of different varieties grown in the conditions of the Republic of Adygea on the basis of a study of organoleptic, physicochemical and biochemical indicators. Materials and methods. The objects of the study were samples of apple fruits of the agricultural enterprise LLC “Yumiks” of 5 varieties: Braeburn, Granny Smith, Idared, Florina, Simirenko, grown in the conditions of the Republic of Adygea. In the samples under study, the determination of organoleptic, physicochemical and biochemical parameters was carried out: soluble solids (SS), titratable acids per malic acid, vitamin C, total sugars, iron, polyphenol oxidase activity, antioxidant activity (AOA). Statistical data processing was carried out in MS Excel 2016. Results. For the first time, on the basis of a complex of organoleptic, physicochemical and biochemical methods, studies of apple varieties grown in the Republic of Adygea were carried out: Florina, Idared, Granny Smith, Braeburn, Simirenko. It has been established that the highest index of sensory quality has apple varieties Braeburn and Simirenko, the Braeburn variety is distinguished by a high content of solids and sugars, more harmonious taste, i.e. the optimal ratio of sugar to acid is found in the Braeburn and Florina varieties. The highest content of vitamin C and bioavailable iron is characteristic of Braeburn and Simirenko apple varieties. Polyphenol oxidase activity in Simirenko, Idared and Florina varieties was higher than in samples of other varieties, while a higher AOA value was found in Granny Smith. Conclusion. The data obtained by us on the basis of a comprehensive study of apple varieties new to the Republic of Adygea, but already in a certain consumer demand, will allow us to give an objective assessment of their contribution to the biological value of the diets of various population groups, and also, subject to further monitoring studies, can be used gardeners of the Republic of Adygea when expanding the area under varieties with the highest taste and stable indicators of biological value

От тройной к пятеричной спирали: эволюция методологии развития инновационной экономики

The presented paper deals with an approach to the evolution of methodology of economy innovative development from the standpoint of analyzing the interaction of its actors – from a Triple to a Penta Helix. The article proposes the provisions for such a methodology based on expanding the range of actors of innovative development as public interests shift from the emergence of a free enterprise economy to a socially oriented knowledge economy and further to a balanced and environmentally friendly production and consumption. A special role in the presented approach is given to the analysis of the place of universities in the fivefold spiral of innovative transformation of economy – as a creator of sustainable development values. The authors proved that the Penta Helixis the result of the evolution of the Quadruple Helix in the conditions of increasing the values of sustainable development. In turn, the core of the QuadrupleHelix– the Triple Helix– acts as the core in the Penta Helix. The article highlights three varieties of the TripleHelix model that is dominant today in industrialized countries, shows their connection with the peculiarities of the innovative development of the Russian economy. On this basis, it was concluded that the progress in building the Penta Helix of innovative development in Russia depends on the emergence of new actors – the subjects of the green economy and civil society, and the full expression of their economic interestsВ представленной статье рассматривается подход к эволюции методологии развития инновационной экономики с позиций анализа взаимодействия ее акторов – от тройной к пятеричной спирали. В статье предлагаются положения методологии, основанной на расширении круга акторов инновационного развития по мере смещения общественного интереса от становления экономики свободного предпринимательства к социально ориентированной экономике знаний и далее – к сбалансированному и экологически безопасному производству и потреблению. Особая роль в представленном подходе отводится анализу места университетов в пятеричной инновационной трансформации экономики – как создателей ценностей устойчивого развития. Авторы доказали, что пятеричная спираль является результатом эволюции четверной спирали инноваций в условиях повышения роли ценностей устойчивого развития. В свою очередь, ядро четверной спирали – тройная спираль – действует и как ядро пятеричной спирали. В статье выделены три разновидности модели тройной спирали, доминирующей сегодня в промышленно развитых странах, показана их связь с особенностями инновационного развития российской экономики. На этом основании сделан вывод, что прогресс в формировании пятеричной спирали инновационного развития в России зависит от появления новых акторов – субъектов зеленой экономики и гражданского общества, полноты выражения их экономических интересо

Erot spatiaalisissa ja ajallisissa reaktionormeissa kevään ja syksyn fenologisille tapahtumille

For species to stay temporally tuned to their environment, they use cues such as the accumulation of degree-days. The relationships between the timing of a phenological event in a population and its environmental cue can be described by a population-level reaction norm. Variation in reaction norms along environmental gradients may either intensify the envi- ronmental effects on timing (cogradient variation) or attenu- ate the effects (countergradient variation). To resolve spatial and seasonal variation in species’ response, we use a unique dataset of 91 taxa and 178 phenological events observed across a network of 472 monitoring sites, spread across the nations of the former Soviet Union. We show that compared to local rates of advancement of phenological events with the advancement of temperature-related cues (i.e., variation within site over years), spatial variation in reaction normsPeer reviewe

The efficacy of augmented reality exposure therapy in the treatment of spider phobia—a randomized controlled trial

The evidence for the use of Augmented Reality (AR) in treating specific phobias has been growing. However, issues of accessibility persist, especially in developing countries. The current study examined a novel, but relatively simple therapist guided smartphone-based AR Exposure Treatment (ARET) of spider phobia. Participants who reported symptoms of Arachnophobia were randomized into one of three comparison groups: ARET (n = 20), traditional in vivo exposure therapy (IVET; n = 18) and a waitlist control group (n = 17). Behavioral approach, subjective symptom measures, and galvanic skin response were assessed pre- and post-treatment. The study was concluded with a one-month follow up assessment. Results indicated that both treatment groups showed statistically significant and clinically meaningful improvements in behavioral approach at post-test that were maintained at 1 month follow- up, compared to the wait-listed group. Moreover, the treatment groups demonstrated significant improvements in subjective symptom report at 1-month follow up. Given its utility and potential accessibility, our findings suggest that future AR evaluation research could be conducted in therapy settings with minimal resources

Airway basal cells from human-induced pluripotent stem cells: a new frontier in cystic fibrosis research

Human-induced airway basal cells (hiBCs) derived from human-induced pluripotent stem cells (hiPSCs) offer a promising cell model for studying lung diseases, regenerative medicine, and developing new gene therapy methods. We analyzed existing differentiation protocols and proposed our own protocol for obtaining hiBCs, which involves step-by-step differentiation of hiPSCs into definitive endoderm, anterior foregut endoderm, NKX2.1+ lung progenitors, and cultivation on basal cell medium with subsequent cell sorting using the surface marker CD271 (NGFR). We derived hiBCs from two healthy cell lines and three cell lines with cystic fibrosis (CF). The obtained hiBCs, expressing basal cell markers (NGFR, KRT5, and TP63), could differentiate into lung organoids (LOs). We demonstrated that LOs derived from hiBCs can assess cystic fibrosis transmembrane conductance regulator (CFTR) channel function using the forskolin-induced swelling (FIS) assay. We also carried out non-viral (electroporation) and viral (recombinant adeno-associated virus (rAAV)) serotypes 6 and 9 and recombinant adenovirus (rAdV) serotype 5 transgene delivery to hiBCs and showed that rAAV serotype 6 is most effective against hiBCs, potentially applicable for gene therapy research

Chronicles of nature calendar, a long-term and large-scale multitaxon database on phenology

We present an extensive, large-scale, long-term and multitaxon database on phenological and climatic variation, involving 506,186 observation dates acquired in 471 localities in Russian Federation, Ukraine, Uzbekistan, Belarus and Kyrgyzstan. The data cover the period 1890-2018, with 96% of the data being from 1960 onwards. The database is rich in plants, birds and climatic events, but also includes insects, amphibians, reptiles and fungi. The database includes multiple events per species, such as the onset days of leaf unfolding and leaf fall for plants, and the days for first spring and last autumn occurrences for birds. The data were acquired using standardized methods by permanent staff of national parks and nature reserves (87% of the data) and members of a phenological observation network (13% of the data). The database is valuable for exploring how species respond in their phenology to climate change. Large-scale analyses of spatial variation in phenological response can help to better predict the consequences of species and community responses to climate change.Peer reviewe