Olfactometric techniques in feed analysis: preliminary calibration of DON in durum wheat

Approcci olfattometrici nell\u2019analisi dei mangimi: calibrazione preliminare per il rilievo di DON nel grano duro. Le analisi olfattometriche, attraverso l\u2019uso del naso elettronico, trovano sempre pi\uf9 spazio nella valutazione della qualit\ue0 e sicurezza in campo alimentare. I principali vantaggi di tale approccio risiedono nella sua flessibilit\ue0 di impiego. Una volta messi a punto adeguati protocolli d\u2019analisi e modelli statistici di tipo multivariato, infatti, il naso elettronico si pu\uf2 rivelare uno strumento adatto alle realt\ue0 di campo in quanto caratterizzato da rapidit\ue0 e basso costo d\u2019esercizio. Lo scopo di questo lavoro \ue8 stato quello di verificare, a livello preliminare, l\u2019efficienza del naso elettronico nel riconoscere la presenza di micotossina deossinivalenolo (DON) in 10 campioni di grano duro (Triticum durum) di diversa provenienza geografica. I risultati hanno dimostrato che il protocollo applicato consente di riconoscere la presenza di DON nonch\ue9 di discriminare i diversi campioni in funzione del loro livello di contaminazione

the effect of plant polyphenols on the antioxidant defence system of weaned piglets subjected to an escherichia coli challenge

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the effect of different selenium sources during the finishing phase on beef quality

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Clinical characteristics and outcomes of vaccinated patients hospitalised with SARS-CoV-2 breakthrough infection: Multi-IPV, a multicentre study in Northern Italy

Background: Despite the well-known efficacy of anti-COVID-19 vaccines in preventing morbidity and mortality, several vaccinated individuals are diagnosed with SARS-CoV-2 breakthrough infection, which might require hospitalisation. This multicentre, observational, and retrospective study aimed to investigate the clinical characteristics and outcomes of vaccinated vs. non -vaccinated patients, both hospitalised with SARS-CoV-2 infection in 3 major hospitals in Northern Italy. Methods: Data collection was retrospective, and paper and electronic medical records of adult patients with a diagnosed SARS-CoV-2 infection were pseudo-anonymised and analysed. Vaccinated and non -vaccinated individuals were manually paired, using a predetermined matching criterion (similar age, gender, and date of hospitalisation). Demographic, clinical, treatment, and outcome data were compared between groups differing by vaccination status using Pearson's Chi-square and Mann -Whitney tests. Moreover, multiple logistic regression analyses were performed to assess the impact of vaccination status on ICU admission or intra-hospital mortality. Results: Data from 360 patients were collected. Vaccinated patients presented with a higher prevalence of relevant comorbidities, like kidney replacement therapy or haematological malignancy, despite a milder clinical presentation at the first evaluation. Non -vaccinated patients required intensive care more often than their vaccinated counterparts (8.8% vs. 1.7%, p = 0.002). Contrariwise, no difference in intra-hospital mortality was observed between the two groups (19% vs. 20%, p = 0.853). These results were confirmed by multivariable logistic regressions, which showed that vaccination was significantly associated with decreased risk of ICU admission (aOR=0.172, 95%CI: 0.039-0.542, p = 0.007), but not of intra-hospital mortality (aOR=0.996, 95%CI: 0.582-1.703, p = 0.987). Conclusions: This study provides real -world data on vaccinated patients hospitalised with COVID-19 in Northern Italy. Our results suggest that COVID-19 vaccination has a protective role in individuals with higher risk profiles, especially regarding the need for ICU admission. These findings contribute to our understanding of SARS-CoV-2 infection outcomes among vaccinated individuals and emphasise the importance of vaccination in preventing severe disease, particularly in those countries with lower first -booster uptake rates