Spectroelectrochemical Sensor for Pertechnetate Applicable to Hanford and Other DOE Sites

The general aim of our work funded by DOE is the design and implementation of a new sensor technology that offers the unprecedented levels of specificity needed for analysis of the complex chemical mixtures found at DOE sites nationwide. The sensor is based on a unique combination of electrochemistry, spectroscopy and selective partitioning into a film that collectively provide an extraordinary level of selectivity for the target analyte. Our goal is a reversible sensor in which the fluorescent Tc-complex formed in the film is re-oxidized to TcO4 ? and free ligand. TcO4 ? in the film would then re-equilibrate with the sample. The sensor would therefore satisfy requirements for both applications described above. Making significant progress towards this goal has required us to discover new chemistry and spectroscopy for technetium itself. Indeed, we needed to find the first technetium complexes which fluoresced in solution at room temperature ? we have made that breakthrough discovery this last year. We are now in the unique position of being able to reach our goal of a reversible sensor for Tc

Benign Chondroblastoma Of The Parotid Region: Case Report

Benign chondroblastoma is a very rare bone neoplasm localized especially in the head and neck and accounting for less than 1% of all bone tumors. It affects more frequently the long bones of young patients, at their epiphyseal zones, mainly the lower extremities. A case of benign chondroblastoma of the temporal bone in a young female patient, misdiagnosed as a benign parotid tumor, is presented. The patient first presented at our institute with a 12-month complaint of a mass, hard, painful and fixed, at her left parotid region. The main symptoms related to this pathology, such as hearing loss, otalgia, tinnitus, headache, and others, were not present in this case. Since 2 fine needle aspiration biopsies were inconclusive, a superficial parotidectomy with frozen biopsy at the operating room was proposed. A hard, light-gray, fixed tumor was found in the deep parotid lobe, in close proximity with the mid portion of the zygomatic arc. The frozen biopsy was suggestive of carcinoma, thus the patient underwent a total parotidectomy with resection of the zygomatic arc and sacrifice of the temporal branch of the facial nerve, which was involved by the tumor. The clinical course of chondroblastoma, the radiological studies performed, the surgical planning and the patient's outcome are discussed.1813941Ewing, J., (1928) The Classification and Treatment of Bone Sarcoma. Report of the International Conference on Cancer, pp. 365-376. , London: John Wright & Son, Ltd. BristolCodman, E., Epiphyseal chondromatous giant cell tumors of the upper end of the humerus (1931) Surg Gynecol Obstet, 52, pp. 543-548Jaffe, H.L., Lichtenstein, L., Benign chondroblastoma of bone: A reinterpretation of the so-called calcifying or chondromatous giant cell tumor (1942) Am J Pathol, 18, pp. 969-991Dahlin, D., Ivins, J., Benign chondroblastoma. A study of 125 cases (1972) Cancer, 30, pp. 401-413Bertoni, F., Unni, K.K., Beabout, J.W., Harner, S.G., Dahlin, D.C., Chondroblastoma of the skull and facial bones (1987) Am J Clin Pathol, 88, pp. 1-9Varvares, M.A., Cheney, M.L., Goodman, M.L., Ceisler, E., Montgomery, W.W., Chondroblastoma of the temporal bone. Case report and literature review (1992) Ann Otol Rhinol Laryngol, 101, pp. 763-769Fares, G., Aidan, P., Bouccara, D., Molas, G., Gomulinski, L., Sterkers, O., Chondroblastoma of the temporal bone. Apropos of a case (1997) Ann Otolaryngol Chir Cervicofac, 114, pp. 130-133Flowers, C.H., Rodriguez, J., Naseem, M., Reyes, M.M., Verano, A.S., MR of benign chondroblastoma of the temporal bone (1995) AJNR Am J Neuroradiol, 16, pp. 414-416Fadda, M., Manunta, A., Rinonapoli, G., Zirattu, G., De Santis, E., Ultrastructural appearance of chondroblastoma (1985) Int Orthop, 18, pp. 389-392Monda, L., Wick, M.R., S-100 protein immunostaining in the differential diagnosis of chondroblastoma (1985) Hum Pathol, 16, pp. 287-293Jambhekar, N.A., Desai, P.B., Chitale, D.A., Patil, P., Arya, S., Benign metastasizing chondroblastoma: A case report (1998) Cancer, 82, pp. 675-67

Extra-anatomical Arterial Bypass With Leiomyosarcoma Of The Thigh [derivação Arterial Extra-anatômica Associada à Leiomiossarcoma De Coxa]

Extra-anatomical bypass is a technical option feasible when anatomical pathways are contraindicated or considered of high risk. In this paper we report a case of soft tissue sarcoma in the proximal third of the left lower extremity involving the femoral vessels. The patient was submitted to an extra-anatomical bypass from the external iliac artery to the popliteal artery with PTFE. She was then submitted to en bloc resection of the tumor, quadriceps muscle and femoral vessels. After a 24-month follow-up period the patient has patent PTFE graft and no evidence of local recurrence. Copyright © 2005 by Sociedade Brasileira de Angiologia e Cirurgia Vascular.42205208Eilber, F.R., Morton, K.L., Eckhardt, J., Grant, T., Weisenburger, T., Limb salvage for skeletal and soft tissue sarcoma: Multidisciplinary preoperative therapy (1983) Cancer, 53, pp. 2579-2584McKee, M.D., Liu, D.F., Brooks, J.J., Gibbs, J.F., Driscoll, D.L., Kraybill, W.G., The prognostic significance of margin width for extremity and trunk sarcoma (2004) J Surg Oncol, 85, pp. 68-76Ascer, E., Veith, F.J., Extra-anatomic bypasses (1996) Haimovici's Vascular Surgery, pp. 688-699. , Haimovici H, editor. Cambridge, MA: Blackwell Science, IncStojadinovic, A., Jaques, D.P., Leung, D.H., Healey, J.H., Brennan, M.F., Amputation for recurrent soft tissue sarcoma of the extremity: Indications and outcome (2001) Ann Surg Oncol, 8, pp. 509-518Davidovic, L.B., Kuzmanovic, I.B., Kostic, D.M., An obturator or "lateral" bypass in infected vascular prostheses in the groin? (2002) Srp Arh Celok Lek, 130 (1-2), pp. 27-32Papon, X., Villapadierna, F., Fournier, H.D., Brillu, C., Vialle, R., Mercier, P., High and low lateral approaches to the popliteal artery (1999) Surg Radiol Anat, 21, pp. 365-370Hoballah, J.J., Chalmers, R.T., Sharp, W.J., Kresowik, T.F., Martinasevic, M.M., Corson, J.D., Lateral approach to the popliteal and crural vessels for limb salvage (1996) Cardiovasc Surg, 4, pp. 165-168Padberg Jr., F.T., Lateral approach to the popliteal artery (1998) Ann Vasc Surg, 2, pp. 397-401Veith, F.J., Ascer, E., Gupte, S.K., Wengerter, K.R., Lateral approach to the popliteal artery (1987) J Vasc Surg, 6, pp. 119-123Nambisan, R.N., Karakousis, C.P., Vascular reconstruction for limb salvage in soft tissue sarcomas (1987) Surgery, 101, pp. 668-677Chammas, R., Aspectos fisiopatológicos da disseminação de sarcoma (1999) Sarcoma de Partes Moles, pp. 31-40. , Lopes A, editor. Rio de Janeiro: MedsiHohenberger, P., Allenberg, J.R., Schlag, P.M., Reichardt, P., Results of surgery and multimodal therapy for patients with soft tissue sarcoma invading to vascular structures (1999) Cancer, 85, pp. 396-40

Search for new Higgs bosons via same-sign top quark pair production in association with a jet in proton-proton collisions at s=13TeV

A search is presented for new Higgs bosons in proton-proton (pp) collision events in which a same-sign top quark pair is produced in association with a jet, via the pp→tH/A→ttc‾ and pp→tH/A→ttu‾ processes. Here, H and A represent the extra scalar and pseudoscalar boson, respectively, of the second Higgs doublet in the generalized two-Higgs-doublet model (g2HDM). The search is based on pp collision data collected at a center-of-mass energy of 13 TeV with the CMS detector at the LHC, corresponding to an integrated luminosity of 138fb−1. Final states with a same-sign lepton pair in association with jets and missing transverse momentum are considered. New Higgs bosons in the 200–1000 GeV mass range and new Yukawa couplings between 0.1 and 1.0 are targeted in the search, for scenarios in which either H or A appear alone, or in which they coexist and interfere. No significant excess above the standard model prediction is observed. Exclusion limits are derived in the context of the g2HDM

Search for new heavy resonances decaying to WW, WZ, ZZ, WH, or ZH boson pairs in the all-jets final state in proton-proton collisions at s=13TeV

A search for new heavy resonances decaying to WW, WZ, ZZ, WH, or ZH boson pairs in the all-jets final state is presented. The analysis is based on proton-proton collision data recorded by the CMS detector in 2016–2018 at a centre-of-mass energy of 13 TeV at the CERN LHC, corresponding to an integrated luminosity of 138fb−1. The search is sensitive to resonances with masses between 1.3 and 6TeV, decaying to bosons that are highly Lorentz-boosted such that each of the bosons forms a single large-radius jet. Machine learning techniques are employed to identify such jets. No significant excess over the estimated standard model background is observed. A maximum local significance of 3.6 standard deviations, corresponding to a global significance of 2.3 standard deviations, is observed at masses of 2.1 and 2.9 TeV. In a heavy vector triplet model, spin-1 Z′ and W′ resonances with masses below 4.8TeV are excluded at the 95% confidence level (CL). These limits are the most stringent to date. In a bulk graviton model, spin-2 gravitons and spin-0 radions with masses below 1.4 and 2.7TeV, respectively, are excluded at 95% CL. Production of heavy resonances through vector boson fusion is constrained with upper cross section limits at 95% CL as low as 0.1fb

Measurement of the tt¯ charge asymmetry in events with highly Lorentz-boosted top quarks in pp collisions at s=13 TeV

The measurement of the charge asymmetry in top quark pair events with highly Lorentz-boosted top quarks decaying to a single lepton and jets is presented. The analysis is performed using proton-proton collisions at s=13TeV with the CMS detector at the LHC and corresponding to an integrated luminosity of 138 fb−1. The selection is optimized for top quarks produced with large Lorentz boosts, resulting in nonisolated leptons and overlapping jets. The top quark charge asymmetry is measured for events with a tt¯ invariant mass larger than 750 GeV and corrected for detector and acceptance effects using a binned maximum likelihood fit. The measured top quark charge asymmetry of (0.42−0.69+0.64)% is in good agreement with the standard model prediction at next-to-next-to-leading order in quantum chromodynamic perturbation theory with next-to-leading-order electroweak corrections. The result is also presented for two invariant mass ranges, 750–900 and >900GeV