353 research outputs found
Spotlight on Scholarly Commons, June 2017 - Worldwide
Faculty with notable downloads: Aman Gupta Kelly Whealan-George James Marion, Jr. Tracey Richardson Matthew Earnhardt Brent Terwilliger Dennis Vincenzi David Ison Kenneth Witcher David Thirtyacre Adeel Khalid
Worldwide Faculty Submission Statistics: Total Papers: 49 All-time Downloads: 12,715 June Downloads: 368
*Statistics are for the Worldwide Campus publication
Spotlight on Scholarly Commons, June 2017 - Prescott
Faculty with notable downloads: Timothy Holt Mohammad Moallemi Linda Wieland Matt Earnhardt Sonya McMullen
Prescott Faculty Submission Statistics: Total Papers: 148 All-time Downloads: 84,574 June Downloads: 1,189
Other Interesting Information: Issues of the Pioneer, ERAU Prescott\u27s official newspaper 1978-1983 have been digitized and published. Several SelectedWorks sites have been created.
*Statistics are for the Prescott Campus publication
Spotlight on Scholarly Commons, June 2017 - Daytona Beach
Faculty with notable downloads: Anke Arnaud Gary Kessler Guy Smith William Barott William Lahneman
Daytona Beach Faculty Submission Statistics: Total Papers: 553 All-time Downloads: 61,693 June Downloads: 1,738
Other Interesting Information: The LHUFT Center and ICAEA were brought online.
*Statistics are for the Daytona Beach Campus publication
Scholarly Commons Annual Report 2017-2018
Scholarly Commons continues to showcase ERAU research globally. While the number of submissions increased by 11.85% over FY 17, downloads grew by 43.89% in FY 18. In addition, new conferences, such as the 2018 International Civil Aviation English Association (ICAEA) and ERAU’s AviAsian Conference, were added. The annual ICAEA Conference is held in a different international location each year and the Daytona Beach Campus served as the host this year. The AviAsian Conference is sponsored on ERAU’s Singapore Campus by faculty from that area
Fully coupled photochemistry of the deuterated ionosphere of Mars and its effects on escape of H and D
Although deuterium (D) on Mars has received substantial attention, the
deuterated ionosphere remains relatively unstudied. This means that we also
know very little about non-thermal D escape from Mars, since it is primarily
driven by excess energy imparted to atoms produced in ion-neutral reactions.
Most D escape from Mars is expected to be non-thermal, highlighting a gap in
our understanding of water loss from Mars. In this work, we set out to fill
this knowledge gap. To accomplish our goals, we use an upgraded 1D
photochemical model that fully couples ions and neutrals and does not assume
photochemical equilibrium. To our knowledge, such a model has not been applied
to Mars previously. We model the atmosphere during solar minimum, mean, and
maximum, and find that the deuterated ionosphere behaves similarly to the
H-bearing ionosphere, but that non-thermal escape on the order of 8000-9000
cms dominates atomic D loss under all solar conditions. The total
fractionation factor, , is --0.07, and integrated water loss is
147--158 m GEL. This is still less than geomorphological estimates. Deuterated
ions at Mars are likely difficult to measure with current techniques due to low
densities and mass degeneracies with more abundant H ions. Future missions
wishing to measure the deuterated ionosphere in situ will need to develop
innovative techniques to do so.Comment: 37 pages, 8 figures, published in Journal of Geophysical Research:
Planet
Control of a Programmed Cell Death Pathway in Pseudomonas aeruginosa by an Antiterminator
In Pseudomonas aeruginosa the alp system encodes a programmed cell death pathway that is switched on in a subset of cells in response to DNA damage and is linked to the virulence of the organism. Here we show that the central regulator of this pathway, AlpA, exerts its effects by acting as an antiterminator rather than a transcription activator. In particular, we present evidence that AlpA positively regulates the alpBCDE cell lysis genes, as well as genes in a second newly identified target locus, by recognizing specific DNA sites within the promoter, then binding RNA polymerase directly and allowing it to bypass intrinsic terminators positioned downstream. AlpA thus functions in a mechanistically unusual manner to control the expression of virulence genes in this opportunistic pathogen
Age and diet shape the genetic architecture of body weight in diversity outbred mice.
Understanding how genetic variation shapes a complex trait relies on accurately quantifying both the additive genetic and genotype-environment interaction effects in an age-dependent manner. We used a linear mixed model to quantify diet-dependent genetic contributions to body weight measured through adulthood in diversity outbred female mice under five diets. We observed that heritability of body weight declined with age under all diets, except the 40% calorie restriction diet. We identified 14 loci with age-dependent associations and 19 loci with age- and diet-dependent associations, with many diet-dependent loci previously linked to neurological function and behavior in mice or humans. We found their allelic effects to be dynamic with respect to genomic background, age, and diet, identifying several loci where distinct alleles affect body weight at different ages. These results enable us to more fully understand and predict the effectiveness of dietary intervention on overall health throughout age in distinct genetic backgrounds
Nonthermal hydrogen loss at Mars: Contributions of photochemical mechanisms to escape and identification of key processes
Hydrogen loss to space is a key control on the evolution of the Martian
atmosphere and the desiccation of the red planet. Thermal escape is thought to
be the dominant loss process, but both forward modeling studies and remote
sensing observations have indicated the presence of a second,
higher-temperature "nonthermal" or "hot" hydrogen component, some fraction of
which also escapes. Exothermic reactions and charge/momentum exchange processes
produce hydrogen atoms with energy above the escape energy, but H loss via many
of these mechanisms has never been studied, and the relative importance of
thermal and nonthermal escape at Mars remains uncertain. Here we estimate
hydrogen escape fluxes via 47 mechanisms, using newly-developed escape
probability profiles. We find that HCO dissociative recombination is the
most important of the mechanisms, accounting for 30-50% of the nonthermal
escape. The reaction CO + H is also important, producing roughly as
much escaping H as momentum exchange between hot O and H. Total nonthermal
escape from the mechanisms considered amounts to 39% (27%) of thermal escape,
for low (high) solar activity. Our escape probability profiles are applicable
to any thermospheric hot H production mechanism and can be used to explore
seasonal and longer-term variations, allowing for a deeper understanding of
desiccation drivers over various timescales. We highlight the most important
mechanisms and suggest that some may be important at Venus, where nonthermal
escape dominates and much of the literature centers on charge exchange
reactions, which do not result in significant escape in this study.Comment: 47 pages, 4 figures, 3 tables. Accepted manuscript. An edited version
of this paper was published by AG
Potassium disorders--clinical spectrum and emergency management
Summary Potassium disorders are common and may precipitate cardiac arrhythmias or cardiopulmonary arrest. They are an anticipated complication in patients with renal failure, but may also occur in patients with no previous history of renal disease. They have a broad clinical spectrum of presentation and this paper will highlight the life-threatening arrhythmias associated with both hyperkalaemia and hypokalaemia. Although the medical literature to date has provided a foundation for the therapeutic options available, this has not translated into consistent medical practice. Treatment algorithms have undoubtedly been useful in the management of other medical emergencies such as cardiac arrest and acute asthma. Hence, we have applied this strategy to the treatment of hyperkalaemia and hypokalaemia which may prove valuable in clinical practice
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